PREGADOC NT 75MG/10MG TABLET

PREGADOC NT 75MG/10MG TABLET is a combination medication prescribed for the treatment of severe neuropathic pain. It is also used for the management of neuropathic disorders like diabetic peripheral neuropathy, postherpetic neuralgia, and spinal cord injury.

It works by binding to a certain region of the brain and reducing the pain signals sent out by the damaged nerves of the body. This medicine is also utilised for treating restless leg syndrome, epilepsy, shingles, seizures, fibromyalgia and generalised anxiety disorder.

This medication is not recommended for you if you are pregnant, or have an allergic reaction towards any of its ingredients. Some medicines interact with it. Inform your doctor if you are taking any of the following:

• Angiotensin- converting enzyme inhibitors
• Benzodiazepines or narcotic pain medicines
• Thiazolidinedione antidiabetic agents

Ensure your doctor is informed if you have any of the following medical conditions before starting the medication:

• If you have congestive heart failure, irregular heartbeat, diabetes, bleeding problems, muscle problems, highballed pressure or low platelet count.
• If you have improper kidney functioning or are on dialysis.
• If you have a history of angioedema.
• If you are pregnant, planning to be pregnant or are breastfeeding.
• If you take any other medicines, dietary supplements or herbal preparations.
• If you have mental or mood problems, suicidal thoughts, or are dealing with depression.

The dose for this medication may vary according to the age, sex, pathological conditions and other factors. The dosage can later be increased depending on efficacy and tolerability of the patient.

• Neuropathic Pain

• Diabetic Peripheral Neuropathy

• Postherpetic Neuralgia

• Allergy

• Myocardial Infarction

• Dizziness

• Dry Mouth

• Weight Gain

• Drowsiness

• Peripheral Edema

• Nausea

• Blurred Vision

• How long is the duration of effect?

  The effect of this medicine lasts for an average duration of 10-12 hours.

• What is the onset of action?

  This medicine has a varying onset time depending on the intended use.

• Are there any pregnancy warnings?

  Pregnant women must consult doctor before using this medication.

• Is it habit forming?

  This medicine has a low abuse potential with limited physical and psychological dependence.

• Are there any breast-feeding warnings?

  Use of this medication by breastfeeding women is not recommended. Consult your doctor before using this medicine.

Below is the list of medicines, which have the same composition, strength and form as PREGADOC NT 75MG/10MG TABLET , and hence can be used as its substitute.

• Pretyline 75Mg/10Mg Tablet

  Carise Pharmaceuticals Pvt Ltd

• Nuromark Pnt 75Mg/10Mg Tablet

  Unimarck Healthcare Ltd

• Neurotin-Nt Tablet

  Medsol India Overseas Pvt Ltd

• Pregamax Nt 75Mg/10Mg Tablet

  Winmark Pharmaceuticals Pvt Ltd

• Preganza Nt Tablet

  Emcure Pharmaceuticals Ltd

• Megabid Nt 75Mg/10Mg Tablet

  Ordain Health Care Global Pvt Ltd

• Gabacure Nt 75Mg/10Mg Tablet

  HBC Lifesciences Pvt Ltd

• Pregalift Nt 75 Mg/10 Mg Tablet

  Linux Laboratories

• Zylin Nt 75 Mg/10 Mg Tablet

  Zydus Cadila

• NERVILAX NT 75MG/10MG TABLET

  Saffron Therapeutics Pvt Ltd

• Are there any missed dose instructions?

  Take the missed dose as soon as you remember. If it is almost time for the next scheduled dose then the missed dose can be skipped.

• Are there any overdose instructions?

  Contact your doctor immediately if an overdose is suspected.

This medication is a combination of Pregabalin and Nortriptyline, thus work through a dual mechanism of action. Primarily, it behaves as a GABA analogue and binds to the voltage-gated calcium channels in the central nervous system. This causes a reduced release of neurotransmitters like serotonin, dopamine, substance P thus slowing down nerve signals. Secondarily, it blocks the serotonin reuptake at the neuronal membrane. Also, it inhibits the reuptake of norepinephrine and raises its concentration in the synaptic cleft.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  Ethanol

  Avoid or limit the use of alcohol while taking this medicine. One should refrain from operating heavy machinery or performing works that require a high level of mental alertness.

• Interaction with Lab Test

  Lab

  Information not available.

• Interaction with Medicine

  Medicine

  This medication interacts with Glimepiride, Linezolid, Lorazepam, Ondansetron and others.

• Interaction with Food

  Food

  Information not available.

• Interaction with Disease

  Disease

  This medication interacts with Heart Disease, Angioedema and others.

• Ques : What is PREGADOC NT 75MG/10MG TABLET?

  Ans : This medication is a combination of Pregabalin and Nortriptyline and is considered to be the first-line of treatment for neurotic pain, shingles, seizures and fibromyalgia.

• Ques : What are the uses of PREGADOC NT 75MG/10MG TABLET?

  Ans : Pregadoc is used for the treatment and prevention from conditions such as Diabetic Neuropathy, Postherpetic Neuralgia, Epilepsy, and Fibromyalgia.

• Ques : What are the Side Effects of PREGADOC NT 75MG/10MG TABLET?

  Ans : Side effects include Difficulty in breathing, Chest tightness, Chills, Severe diarrhea, Swelling of face, lips, eyelids, tongue, hands and feet , Unusual tiredness and weakness, Blurred or double vision, Allergic skin reaction, Dizziness, Dry mouth, Headache, Memory problem, Loss of coordination, Fever, Loss of appetite, Anxiety and nervousness, and Slurred speech.

• Ques : What are the instructions for storage and disposal PREGADOC NT 75MG/10MG TABLET?

  Ans : Pregadoc should be kept in a cool dry place and in its original pack. Make sure this medication remains unreachable to children and pets.

• Nortriptyline- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 23 January 2020]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/pregabalin

• Pregabalin- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 23 January 2020]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/nortriptyline

• Nortriptyline 10 mg Film-coated Tablets [Internet]. medicines.org.uk 2019 [Cited 23 January 2020]. Available from:

  https://www.medicines.org.uk/emc/medicine/32962