Ranidom RD 15 mg/20 mg Tablet

This medication is indicated for treating GERD (Gastro-esophageal reflux disease), which does not respond to Esomeprazole medications alone. It prevents the tendency of vomiting and nausea in people suffering from gastrointestinal problems.

Ranidom RD 15 mg/20 mg Tablet is a combination of Domperidone and Esomeprazole. The active ingredients fall under the class of dopamine antagonist and PPI (Proton pump inhibitor), respectively.

It is also prescribed to the patients of peptic ulcer and who take certain medicines for Parkinson’s disease. The medicine tightens the muscles near the entrance of the stomach and relaxes the ones present at the exit.

The action of this medication helps to speed up the passing of the food that you intake - from your stomach to your intestine, reducing the feeling of nausea and sickness, also preventing vomiting.

This medicine also works by blocking or reducing the stimulation in the ‘vomiting centre’ of your brain, which will eventually reduce the feeling of nausea and vomiting. The possible side effects of taking this medication can be headache, migraine, dryness of the mouth or breast pain.

You are advised not to take Ranidom RD 15 mg/20 mg Tablet if you have the following conditions:

• An allergy to Ranidom RD 15 mg/20 mg Tablet or any other ingredient of this medicine
• Bleeding problems or blockage in your stomach or in the intestine
• Tumour in the pituitary gland
• Cardiac disease
• Incorrect levels of magnesium, potassium or calcium in the blood
• Severe/moderate liver impairment

• Gastro-Esophageal Reflux Disease (Gerd)

• Peptic Ulcer

• Allergy

• Tumor Of Pituitary Gland

• Heart Diseases

• Skin Rash

• Diarrhoea

• Headache

• Stomach Pain

• Dizziness

• Weakness

• Dry Mouth

• Cough

• Rhinitis

• Flatulence

• Insomnia

• How long is the duration of effect?

  The effect of this medicine lasts up to 6 hours.

• What is the onset of action?

  The peak effect of this medicine can be observed within 30 to 60 minutes of administration.

• Are there any pregnancy warnings?

  This medicine should not be consumed during pregnancy unless necessary.

• Is it habit forming?

  No habit forming tendencies were reported.

• Are there any breast-feeding warnings?

  The medicine should not be consumed by breastfeeding mothers.

• Are there any missed dose instructions?

  Skip the missed dose and resume with the next scheduled dose at the right time.

• Are there any overdose instructions?

  Contact your doctor if an overdose is suspected.

This medication attaches to the dopaminergic receptors without causing any release of the chemical dopamine. It, in turn, facilitates gastric emptying and decreases small bowel transit time. Also, it binds to H+/K+-exchanging ATPase in gastric parietal cells, resulting in blockage of acid secretion.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

test

• Interaction with Lab Test

  The patients taking this medicine have been reported for false results, as it interacts with investigations of Neuroendocrine Tumors, Secretin Stimulation Test, Urine Tests for THC. Thus an alternative confirmatory test should be considered to verify the results.

• Interaction with Medicine

  Medicine

  Concomitant use of Antiretrovirals, warfarin, methotrexate, digoxin, Drugs Dependent on Gastric pH for Absorption (e.g., iron salts, erlotinib, dasatinib, nilotinib, mycophenolate mofetil, ketoconazole, itraconazole), tacrolimus, antiarrhythmics, apomorphine, protease inhibitors, systemic azole antifungals, some macrolides (erythromycin, clarithromycin and telithromycin) is contraindicated.

• Interaction with Disease

  Disease

  Patients suffering from intestinal disorders, liver/kidney disease and osteoporosis should exercise caution.

• Ques : What is Ranidom RD 15 mg/20 mg Tablet?

  Ans : This medicine is a combination of Domperidone and Esomeprazole. These drugs are a part of the dopamine antagonists group of drugs and PPI, respectively and prevent the tendency of vomiting and nausea in people suffering from gastrointestinal problems and also those who take certain medicines for Parkinson’s disease. It consists of Domperidone which is an antiemetic agent and is used to treat nausea and vomiting.

• Ques : What are the uses of Ranidom RD 15 mg/20 mg Tablet?

  Ans : Ranidom tablet is used for the treatment and prevention from conditions and symptoms of diseases like gastric ulcers, peptic ulcer, treatment for symptoms associated with idiopathic or diabetic gastroparesis and acidity.

• Ques : What are the Side Effects of Ranidom RD 15 mg/20 mg Tablet?

  Ans : Possible side-effects include a headache, somnolence, akathisia, diarrhea and rash.

• Ques : What are the instructions for storage and disposal Ranidom RD 15 mg/20 mg Tablet?

  Ans : Ranidom tablet should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets.

• Ques : What are the contraindications to Ranidom RD 15 mg/20 mg Tablet?

  Ans : It should not be used if you have the following conditions such as Congestive heart failure, Hypersensitivity to domperidone, Moderate or severe hepatic impairment, Pregnancy, etc.

• Ques : Is Ranidom RD 15 mg/20 mg Tablet safe to use when pregnant?

  Ans : This medication is not recommended for use in pregnant women unless absolutely necessary.

• Ques : Will Ranidom RD 15 mg/20 mg Tablet be more effective if taken in more than the recommended dose?

  Ans : No, taking higher than the recommended dose can lead to increased chances of side effects.

• Esomeprazole- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 24 March 2020]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/esomeprazole

• Esomeprazole- DrugBank [Internet]. Drugbank.ca. 2020 [Cited 24 March 2020]. Available from:

  https://www.drugbank.ca/drugs/DB00736

• Domperidone- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 24 March 2020]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/rn/57808-66-9

• Domperidone- DrugBank [Internet]. Drugbank.ca. 2020 [Cited 24 March 2020]. Available from:

  https://www.drugbank.ca/drugs/DB01184