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Overview

Regorafenib

Prescription vs OTC : Prescription by Doctor required

About Regorafenib

Regorafenib is a drug targeted basically on cancerous diseases. The main method of its function is blocking cancer cells proteins which encourages growth of such cells, hence its also known as cancer growth blocker. FDA in 2017 has expanded the indications of Regorafenib to include hepatocellular carcinoma. It has been also included as a potential cure agent for multiple types of tumor. It is administered to treat and delay tumor growth in patients with gastrointestinal stromal tumors. It is indicated for treating colorectal cancer as well.

Regorafenib comes usually in tablet format which is taken once a day according to the doctor’s advice. It is ideally taken in the same time every day. It has been seen that it is usually prescribed to be taken every day for 3 weeks then 1 week gap is given before restarting the dosage.

Side effects are very alarming in some cases when taken without professional guidance. Severe liver toxicity, bleeding, skin-peeling, blood pressure are some of the serious effects. Weakness, fatigue, loss of appetite, diarrhea, weight loss, infections etc are some common side effects which accompany the drug. Hence it must be taken only under Doctor’s advice.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

    What are the uses of Regorafenib

    • Cancer Of Colon And Rectum

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

    What are the side effects of Regorafenib ?

    • Rash

    • Weakness

    • Reduced Blood Platelets

    • Difficulty In Speaking

    • Haemorrhage

    • Vomiting

    • Pain

    • Nausea

    • Infections

    • Hair Loss

    • Fever

    • Anemia

    • Diarrhoea

    • Increased Blood Pressure

    • Decreased Appetite

    • Mucosal Inflammation

    • Stomatitis (Inflammation Of The Mouth)

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

    Key highlights of Regorafenib

    • Is It safe with alcohol?

      Interaction with alcohol is unknown. Please consult your doctor.

    • Are there any pregnancy warnings?

      Resihance 40mg tablet is unsafe to use during pregnancy.
      There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.

    • Are there any breast-feeding warnings?

      Resihance 40mg tablet is probably unsafe to use during breastfeeding. Please consult your doctor.

    • Is it safe to drive while on this medicine?

      There is no data available. Please consult doctor before consuming the drug.

    • Does this affect kidney function?

      There is no interaction between renal impairment and consuming this drug. So dose alteration is not needed.

    • Does this affect liver function?

      There is no data available. Please consult doctor before consuming the drug.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

    Medicines containing Regorafenib

    Below is the list of medicines, which contains Regorafenib as ingredient

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

    How does this medication work?

    The active constituent of this medicine is a tiny molecule inhibitor of manifold membrane-bound and intracellular kinases associated with normal cellular functions and in pathologic procedures like oncogenesis, tumour angiogenesis, and the retention of the tumour microenvironment.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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