Sompraz D 20 Capsule Sr

This medication is indicated for treating GERD (Gastro-esophageal reflux disease), which does not respond to Esomeprazole medications alone. It prevents the tendency of vomiting and nausea in people suffering from gastrointestinal problems.

Sompraz D 20 Capsule Sr is a combination of Domperidone and Esomeprazole. The active ingredients fall under the class of dopamine antagonist and PPI (Proton pump inhibitor), respectively.

It is also prescribed to the patients of peptic ulcer and who take certain medicines for Parkinson’s disease. The medicine tightens the muscles near the entrance of the stomach and relaxes the ones present at the exit.

The action of this medication helps to speed up the passing of the food that you intake - from your stomach to your intestine, reducing the feeling of nausea and sickness, also preventing vomiting.

This medicine also works by blocking or reducing the stimulation in the ‘vomiting centre’ of your brain, which will eventually reduce the feeling of nausea and vomiting. The possible side effects of taking this medication can be headache, migraine, dryness of the mouth or breast pain.

You are advised not to take Sompraz D 20 Capsule Sr if you have the following conditions:

• An allergy to Sompraz D 20 Capsule Sr or any other ingredient of this medicine
• Bleeding problems or blockage in your stomach or in the intestine
• Tumour in the pituitary gland
• Cardiac disease
• Incorrect levels of magnesium, potassium or calcium in the blood
• Severe/moderate liver impairment

• Gastroesophageal Reflux Disease

• Peptic Ulcer

• Allergy

• Tumor Of Pituitary Gland

• Heart Diseases

• Gastrointestinal Haemorrhage

• Skin Rash

• Diarrhoea

• Headache

• Stomach Pain

• Dizziness

• Weakness

• Dry Mouth

• Cough

• Rhinitis

• Flatulence

• Insomnia

• How long is the duration of effect?

  The effect of this medicine lasts up to 6 hours.

• What is the onset of action?

  The peak effect of this medicine can be observed within 30 to 60 minutes of administration.

• Are there any pregnancy warnings?

  This medicine is not recommended for use in pregnant women.

• Is it habit forming?

  No habit forming tendencies were reported.

• Are there any breast-feeding warnings?

  This medicine is not recommended for use by breastfeeding mothers.

Below is the list of medicines, which have the same composition, strength and form as Sompraz D 20 Capsule Sr , and hence can be used as its substitute.

• Nexpro Rd 20 Capsule Sr

  Torrent Pharmaceuticals Ltd

• Are there any missed dose instructions?

  Skip the missed dose and resume with the next scheduled dose at the right time.

• Are there any overdose instructions?

  Contact your doctor if an overdose is suspected.

This medication attaches to the dopaminergic receptors without causing any release of the chemical dopamine. It, in turn, facilitates gastric emptying and decreases small bowel transit time. Also, it binds to H+/K+-exchanging ATPase in gastric parietal cells, resulting in blockage of acid secretion.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  Alcohol

  Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

• Interaction with Lab Test

  Lab

  The patients taking this medicine have been reported for false results, as it interacts with investigations of Neuroendocrine Tumors, Secretin Stimulation Test, Urine Tests for THC. Thus an alternative confirmatory test should be considered to verify the results.

• Interaction with Medicine

  Concomitant use of Antiretrovirals, warfarin, methotrexate, digoxin, Drugs Dependent on Gastric pH for Absorption (e.g., iron salts, erlotinib, dasatinib, nilotinib, mycophenolate mofetil, ketoconazole, itraconazole), tacrolimus, antiarrhythmics, apomorphine, protease inhibitors, systemic azole antifungals, some macrolides (erythromycin, clarithromycin and telithromycin) is contraindicated.

• Interaction with Food

  Food

  Information not available.

• Interaction with Disease

  Disease

  Patients suffering from kidney or liver disease should use some other safer alternative.

• Ques : What is Sompraz D 20 Capsule Sr?

  Ans : Sompraz capsule sr is a medication which has Domperidone and Esomeprazole as active ingredients present in it. This medicine performs its action by obstructing the production of dopamine (chemical messengers) in the body.

• Ques : What are the uses of Sompraz D 20 Capsule Sr?

  Ans : Sompraz d 20 is used for the treatment and prevention from conditions and symptoms of diseases like peptic ulcer, gastroesophageal reflux diseases, diabetic gastroparesis, and intractable vomiting.

• Ques : What are the Side Effects of Sompraz D 20 Capsule Sr?

  Ans : Breast tenderness, amenorrhea, diarrhea, headache, skin rashes and somnolence are common side effects.

• Ques : What are the instructions for storage and disposal Sompraz D 20 Capsule Sr?

  Ans : Sompraz should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets.

• Ques : Should I use Sompraz D 20 Capsule Sr empty stomach, before food or after food?

  Ans : This medication is to be taken on an empty stomach as any additional nutrient can alter its mechanism of action. Moreover, taking it with the food may cause abdominal discomfort as well.

• Ques : How long do I need to use Sompraz D 20 Capsule Sr before I see improvement of my conditions?

  Ans : There is no specific time duration of using this medication in which you can see improvement in your condition. The doctor will prescribe you the doses according to your condition.

• Ques : Is there any food or drink I need to avoid?

  Ans : The diet should be normal, there is nothing as such to avoid. However, eating healthy, doing physical exercises and avoiding any kind of harmful practices like smoking or drinking can uplift your health.

• Ques : Will Sompraz D 20 Capsule Sr be more effective if taken in more than the recommended dose?

  Ans : Please follow the doses of the medication, as prescribed by your doctor.

• Esomeprazole- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 24 March 2020]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/esomeprazole

• Esomeprazole- DrugBank [Internet]. Drugbank.ca. 2020 [Cited 24 March 2020]. Available from:

  https://www.drugbank.ca/drugs/DB00736

• Domperidone- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 24 March 2020]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/rn/57808-66-9

• Domperidone- DrugBank [Internet]. Drugbank.ca. 2020 [Cited 24 March 2020]. Available from:

  https://www.drugbank.ca/drugs/DB01184