Syndopa Plus 100Mg/25Mg Tablet Md

Syndopa Plus 100Mg/25Mg Tablet Md is used to manage the symptoms of induration, stiffness, tremors, spasms, and poor muscle that can be experienced in the case of Parkinson’s disease. The medication works by increasing the levels of dopamine in the body which helps the person to control the brain movements.

Since the medication is dealing with hormones associated with brain functioning, it might be possible for an individual to experience mental health issues. So it’s important to keep a check on your physical and mental health during the course of this medication.

Do not take this medication if you have a medical history of fits, heart, BP, lung, liver, kidney, blood or hormone problems; allergic reaction to any compound present in the medication. Also, psychological issues like depression or any other psychiatric disorder need to be addressed before the intake of Syndopa Plus 100Mg/25Mg Tablet Md.

Some side effects include hypotension: a result of the dosage being too high, arrhythmias: although this is uncommon, nausea, which can be avoided by taking the drug with food, hair loss, disorientation and, or confusion, an extreme emotional state, particularly anxiety, but also excessive libido.

• Parkinson's Disease

• Hypersensitivity

• Nausea

• Vomiting

• Dryness In Mouth

• Constipation

• Dizziness

• Sleepiness

• Headache

• Abnormal Dreams

• Anxiety

• Insomnia

• Abnormality Of Voluntary Movements

• Orthostatic Hypotension

• Is It safe with alcohol?

  Syndopa Plus 100Mg/25Mg Tablet Md may cause excessive drowsiness and calmness with alcohol.

• Are there any pregnancy warnings?

  Syndopa Plus 100Mg/25Mg Tablet Md may be unsafe to use during pregnancy.
  Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

• Are there any breast-feeding warnings?

  Unknown. Human and animal studies are not available. Please consult your doctor.

• Is it safe to drive while on this medicine?

  Patients who have experienced somnolence and/or an episode of sudden sleep onset must refrain from driving or operating machines.
  Advise patients to exercise caution while driving or operating machinery.

• Does this affect kidney function?

  Syndopa Plus 100Mg/25Mg Tablet Md is probably safe to be use in patients with kidney disease. Available data suggests that adjustment of dose may not be needed. Please consult doctor before consuming the drug.

• Does this affect liver function?

  Caution must be taken in patients with liver disease. Adjustment of dose might be needed. Please consult doctor before consuming the drug.

• Are there any overdose instructions?

  Seek emergency medical treatment or contact the doctor in case of an overdose.

• Are there any missed dose instructions?

  If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

The active constituent of this medication is structurally an amino acid, a precursor of dopamine. Medication is taken orally crosses the blood-brain barrier and is decarboxylated to dopamine, which is then available to activate dopaminergic receptors. This compensates for the reduced supply of dopamine observed in Parkinson’s disease.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

test

• Interaction with Lab Test

  False-positive reaction for urinary glucose with Clinitest®; false-negative reaction using Clinistix®; false-positive urine ketones with Acetest®, Ketostix®, Labstix®.

• Interaction with Medicine

  • Benzodiazepines may inhibit the antiparkinsonian effects of levodopa; monitor for reduced effect.
  • Antipsychotics may inhibit the antiparkinsonian effects of levodopa via dopamine receptor blockade; use antipsychotics with low dopamine blockade (clozapine, olanzapine, quetiapine).
  • High-protein diets may inhibit levodopa's efficacy; avoid high protein diets.
  • Iron binds levodopa and reduces its bioavailability; separate doses of iron and levodopa.
  • Concurrent use of levodopa with nonselective MAOIs may result in hypertensive reactions via an increased storage and release of dopamine, norepinephrine, or both. Use with carbidopa to minimize reactions if combination is necessary; otherwise avoid combination.
  • L-methionine, phenytoin, pyridoxine, and spiramycin may inhibit levodopa's antiparkinsonian effects.
  • Tacrine may inhibit the effects of levodopa via enhanced cholinergic activity; monitor.

• Interaction with Disease

  • Use with caution in patients with history of cardiovascular disease (including myocardial infarction and arrhythmias); pulmonary diseases such as asthma, psychosis, wide-angle glaucoma, peptic ulcer disease; as well as in renal, hepatic, or endocrine disease.
  • Sudden discontinuation of levodopa may cause a worsening of Parkinson's disease. Elderly may be more sensitive to CNS effects of levodopa. May cause or exacerbate dyskinesias. May cause orthostatic hypotension; Parkinson's disease patients appear to have an impaired capacity to respond to a postural challenge.
  • Use with caution in patients at risk of hypotension (such as those receiving antihypertensive drugs) or where transient hypotensive episodes would be poorly tolerated (cardiovascular disease or cerebrovascular disease).
  • Observe patients closely for development of depression with concomitant suicidal tendencies. Safety and effectiveness in pediatric patients have not been established.
  • Some products may contain tartrazine. Dopaminergic agents have been associated with a syndrome resembling neuroleptic malignant syndrome on withdrawal or significant dosage reduction after long-term use.
  • Pyridoxine may reverse effects of levodopa. Toxic reactions have occurred with dextromethorphan.

• Interaction with Food

  High protein diets may decrease the efficacy of levodopa when used for parkinsonism via competition with amino acids in crossing the blood-brain barrier.

• Ques : What are the compounds used to manufacture Syndopa Plus 100Mg/25Mg Tablet Md?

  Ans : Syndopa Plus 100Mg/25Mg Tablet Md is made with a balanced mix of Levodopa and Carbidopa.

• Ques : What are the food products that need to avoid during the consumption of Syndopa Plus 100Mg/25Mg Tablet Md?

  Ans : Avoid foods and drinks that have high protein or iron salt levels. It is also advised to avoid any dairy products during the course of the Syndopa Plus 100Mg/25Mg Tablet Md.

• Ques : Can you crush or chew Syndopa Plus 100Mg/25Mg Tablet Md?

  Ans : No, consume the medication as a whole without doing any physical change in the medication.

• Ques : Can you do activities like driving after the consumption of the Syndopa Plus 100Mg/25Mg Tablet Md?

  Ans : No, you can’t as this tablet does cause drowsiness or dizziness. Also, do certain things like getting out of bed or a set very slowly.

• Ques : What are the withdrawal symptoms of Syndopa Plus 100Mg/25Mg Tablet Md?

  Ans : If the treatment is stopped or paused by the user without any consultation, the body may show severe withdrawal symptoms. Some of them may include fever, stiff muscles, unusual body movements, sweating, and confusion.

• Ques : Is dark urine common while consuming Syndopa Plus 100Mg/25Mg Tablet Md?

  Ans : Yes, body fluids like saliva, sweat, urine, and blood might change the colour. You may experience change or darkening of these fluids into shades of brown, red or black.

• Ques : Can you club Syndopa Plus Table with other medications?

  Ans : It is safe to consume Syndopa Plus Table with most of the medicins except -

  • Adrenaline
  • Alprazolam
  • Amitriptyline
  • Benserazide
  • Biperiden
  • Bupropion
  • Cabergoline
  • Clonidine
  • Dacarbazine
  • Diazepam

• Levodopa- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2021 [Cited 25 Nov 2021]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/levodopa

• Carbidopa- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2021 [Cited 25 Nov 2021]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/rn/28860-95-9

• CARBIDOPA AND LEVODOPA tablet- Daily Med [Internet]. dailymed.nlm.nih.gov. 2020 [Cited 25 Nov 2021]. Available from:

  https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a355d5f2-407d-40fa-a374-b3632261ea4a

• Half Sinemet CR 25 mg/100 mg Prolonged-Release Tablets- EMC [Internet]. www.medicines.org.uk. 2021 [Cited 25 Nov 2021]. Available from:

  https://www.medicines.org.uk/emc/product/10721/smpc