Thiospas-A 4 Tablet

Thiospas-A 4 Tablet is chiefly known as a pain killer. It is primarily used to treat pain caused due to muscle spasm. This medication is a combination of Aceclofenac and Thiocolchicoside.

These two drug belongs to the class of non-steroidal anti-inflammatory drugs and natural anti-inflammatory glycosides, respectively. The drug combination works together and helps in improving muscle movement and also relieves discomfort and pain associated with the spasm.

This drug works by blocking the effect of cyclooxygenase (COX) enzymes which make chemical prostaglandins at sites of injury or damage causing pain, swelling and inflammation.

The side effects of this drug include nausea, vomiting, diarrhoea, flatulence, constipation, dyspepsia, drowsiness, confusion, etc. You should not be taking this medicine if–

• You are allergic to this drug or other anti-inflammatory painkillers.
• You ever had a problem with stomach or duodenal bleeding.
• You have a heart condition or impaired kidney or liver function.
• You are pregnant or breastfeeding woman.
• You have high blood pressure or blood clotting problems.

This medication interacts with medicines like lithium, digoxin, corticosteroids, antihypertensives, etc and certain diseases like asthma, gastrointestinal toxicity. It can be taken with food or after food.

Drinking an adequate amount of water minimises chances of indigestion and stomach irritations. The duration and amount of medicine should be followed as per the doctor’s prescription.

• Muscle Spasm

• Allergy

• Asthma

• Abdominal Pain

• Nausea Or Vomiting

• Skin Rash

• How long is the duration of effect?

  This medication is excreted in urine and the effect lasts for a duration of 12 to 16 hours.

• What is the onset of action?

  The peak effect of this medication can be observed in 1.5 to 3 hours after oral administration.

• Are there any pregnancy warnings?

  This medication is not recommended for pregnant women.

• Is it habit forming?

  No habit forming tendencies were reported.

• Are there any breast-feeding warnings?

  This medication is not recommended for breastfeeding women.

Below is the list of medicines, which have the same composition, strength and form as Thiospas-A 4 Tablet , and hence can be used as its substitute.

• Loyfenac-T 100mg/4mg Tablet

  Lloyd Healthcare Pvt Ltd

• Numol Mr 4 Tablet

  Karnataka Antibiotics & Pharmaceuticals Ltd

• Algic Mr 100Mg/4Mg Tablet

  MSN Laboratories

• Aclof-Th4 Tablet

  Neuron Pharma Pvt Ltd

• Thiopace 4Mg Tablet

  Evaxo Pharma

• Ibicox Mr Tablet

  Indian Drugs & Pharmaceuticals Ltd

• Rhumacort-Th 4 Tablet

  Galpha Laboratories Ltd

• Big Nac Mr 100Mg/4Mg Tablet

  Ronyd Healthcare Pvt Ltd

• Neorelax A 4Mg Tablet

  Meyer Organics Pvt Ltd

• Willgo Th 4 Tablet

  Panacea Biotec Ltd

• Missed Dose instructions

  The missed dose can be taken as soon as you remember. However, the missed dose should be skipped if it is almost time for your next dose.

• Are there any overdose instructions?

  A doctor should be contacted immediately if an overdose of this medication is suspected.

This medication is a combination of Aceclofenac and Thiocolchicoside, thus it works via a dual mechanism of action. The former drug, Aceclofenac, belongs to the class of a non-steroidal anti-inflammatory drug that helps relieve pain. Prostaglandins are responsible for pain, inflammation, swelling and fever. It inhibits the action of cyclooxygenase in the brain which is involved in the production of prostaglandins.

The latter constituent, Thiocolchicoside, is a derivative of glucoside, colchicoside that is contained within the Colchicum autumnale plant. It is a type of synthetic sulphur derivative. This medication has a high affinity for g-aminobutyric acid receptors. It activates GABA pathways and acts on the muscular contractures.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Medicine

  This medication interacts with Lithium, Digoxin, Corticosteroids, and Antihypertensives.

• Interaction with Disease

  This medication interacts with Asthma, Gastro-Intestinal toxicity, Impaired kidney function, and Impaired liver function.

• Ques : What is Thiospas-A 4 Tablet?

  Ans : This medication has Aceclofenac and Thiocolchicoside as active elements present. It performs its action by obstructing the action of cyclooxygenase in the body, decreases the inflammation and pain.

• Ques : What are the uses of Thiospas-A 4 Tablet?

  Ans : This medication is used for the treatment and prevention from conditions such as pain caused by nonarticular rheumatism, muscles stiffness in spinal, muscles stiffness in muscle diseases, rheumatoid arthritis, lumbago, etc.

• Ques : What are the Side Effects of Thiospas-A 4 Tablet?

  Ans : This medication which has some commonly reported side effects such as dyspepsia, abdominal pain, nausea, rash, urticaria, enuresis, headache, dizziness, drowsiness, allergy, urge to vomit, brief loss of consciousness, sleepiness weakness, etc.

• Ques : What are the instructions for storage and disposal Thiospas-A 4 Tablet?

  Ans : Store this medication in a cool dry place and keep it in the original pack or container until it is time to take them. Store this medication out of sight and reach of children. Unused medicines should be disposed of in special ways to ensure that pets, children and other people cannot consume them.

• Ques : How long do I need to use Thiospas-A 4 Tablet before I see improvement of my conditions?

  Ans : This medication takes 1 or 2 days before you see an improvement in your health conditions. It would be ideal if you note, it doesn't mean you will begin to notice such health improvement in a similar time span as different patients.

• Ques : What are the contraindications to Thiospas-A 4 Tablet?

  Ans : Contraindication to thiospas. In addition, this medication should not be used if you have the following conditions such as active peptic ulcer, acute rhinitis, allergy to aceclofenac, asthma, breastfeeding, pregnant, urticaria, etc.

• Ques : Is Thiospas-A 4 Tablet safe to use when pregnant?

  Ans : This medication is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medication.

• Ques : Will Thiospas-A 4 Tablet be more effective if taken in more than the recommended dose?

  Ans : No, taking higher than the recommended dose of this medication can lead to increased chances of side effects such as active peptic ulcer, acute rhinitis, allergy to, aceclofenac, asthma, breastfeeding, pregnant, uticaria, etc.

• Aceclofenac- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 1 February 2020]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/aceclofenac

• Aceclofenac- DrugBank [Internet]. Drugbank.ca. 2010 [Cited 1 February 2020]. Available from:

  https://www.drugbank.ca/drugs/DB06736

• Thiocolchicoside- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 1 February 2020]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/thiocolchicoside

• Thiocolchicoside- DrugBank [Internet]. Drugbank.ca. 2016 [Cited 1 February 2020]. Available from:

  https://www.drugbank.ca/drugs/DB11582