Torsemide

Torsemide treats edema and reduces the presence of extra fluid that develops in the body as a result of health problems like kidney or liver disease and heart failure. Thus, the drug helps in the relief of related symptoms which may include swelling of the abdomen or hand and legs and problems with breathing.

It also effectively treats hypertension, that is, high blood pressure. This medication is known to be a water pill, encouraging the body to create more urine and helps in flushing out the extra liquid and salts.

This medication is mostly prescribed for daily consumption and can be taken before or after food. Patients are generally advised not to take this medication for about 4 hours before bedtime, as you may develop the need to urinate frequently in the middle of the night.

The dosage prescribed to you generally depends on the severity of your condition and how your body reacts to the medicine. It may interfere with your sleeping pattern. In case of patients with edema because of congestive heart failure, the dosage may vary from 10mg - 20mg in a day. Those with renal problems may be prescribed about 20mg daily.

Patients with hypertension are generally prescribed about 5mg-10mg of the drug to be taken once a day. This medication should not be discontinued prior to the doctor’s consent. It is primarily because if you stop taking this medication, it can suddenly aggravate your symptoms. This medication is meant for oral consumption and is available in tablet form.

Take recommended dosage with food or milk at the same time each day (preferably not in the evening to avoid sleep interruption). Do not miss doses, alter dosage, or discontinue without consulting prescriber. Include orange juice or bananas (or other potassium-rich foods) in daily diet; do not take potassium supplements without consulting prescriber.

Do not use alcohol or OTC medications without consulting prescriber. You may experience postural hypotension; change position slowly when rising from sitting or lying.

May cause transient drowsiness, blurred vision, or dizziness; avoid driving or engaging in tasks that require alertness until response to drug is known. You may have reduced tolerance to heat (avoid strenuous activity in hot weather or excessively hot showers).

Increased exercise and increased dietary fiber, fruit, and fluids may reduce constipation. Report unusual weight gain or loss (>5 lb/week), swelling of ankles and hands, persistent fatigue, unresolved constipation or diarrhea, weakness, fatigue, dizziness, vomiting, cramps, change in hearing, or chest pain or palpitations.

Torsemide may cause agranulocytosis; use caution with clozapine and carbamazepine; may decrease lithium clearance resulting in an increase in serum lithium levels and potential lithium toxicity.

However, this is much more common and significant with the thiazide diuretics; monitor serum lithium levels; concurrent use with chloral hydrate may produce hot flashes and hypertension.

Symptoms include electrolyte depletion, volume depletion, hypotension, dehydration, circulatory collapse; electrolyte depletion may be manifested by weakness, dizziness, mental confusion, anorexia, lethargy, vomiting, and cramps.

Following GI decontamination, treatment is supportive; hypotension responds to fluids and Trendelenburg position. Torsemide may induce potent diuretic effects and, as with other potent diuretics, electrolytes and volume status needs to be closely monitored.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

• Edema (Swelling)

  This medication is used in the treatment of edema which is a swelling due to the accumulation of fluid in the hands, feet, and ankles.

• Hypertension

  This medication is used in the treatment of hypertension which is an increase in the blood pressure caused by a fluid overload due to genetic and environmental factors.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

• Allergy

  Avoid taking this medicine if you have a known allergy to it or any other medicine of the same class. Also, avoid taking this medicine if you are allergic to the medicines belonging to the class Sulfonylureas.

• Anuria

  Avoid taking this medicine if you are suffering from Anuria (a condition wherein the kidney is unable to produce urine).

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

• Chest Pain

• Diarrhoea

• Dry Mouth

• Loss Of Appetite

• Muscle Pain

• Nausea Or Vomiting

• Dizziness

• Skin Rash

• Acid Or Sour Stomach

• Increased Cough

• Sleeplessness

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

• How long is the duration of effect?

  The effect of this medicine lasts for an average duration of 6 to 8 hours after an oral dose and 6 hours after an intravenous dose.

• What is the onset of action?

  The peak effect of this medicine can be observed within 1 hour of oral administration.

• Are there any pregnancy warnings?

  This medicine is not recommended for pregnant women.

• Is it habit forming?

  No habit forming tendency has been reported.

• Is It safe with alcohol?

  It is unknown whether the consumption of this medicine along with alcohol is safe or not.

• Is it safe to drive while on this medicine?

  This medicine may affect the alertness of the patient taking it. Thus if you feel dizziness or sleepiness, avoid driving.

• Does this affect kidney function?

  It is safe to use in the patient with kidney disease. For further details consult your doctor.

• Does this affect liver function?

  Caution must be taken in patients with liver disease. Dose adjustment might be needed. Kindly consult your doctor before taking this medication.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

• Missed Dose instructions

  The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.

• Are there any overdose instructions?

  Seek emergency medical treatment or contact the doctor in case of overdose.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

• India

• United States

• Japan

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

Below is the list of medicines, which contains Torsemide as ingredient

• Dytor 10 MG Tablet

  Cipla Ltd

• Tor Kid 20 MG Tablet

  Econ Healthcare Pvt Ltd

• Torsid 10 MG Tablet

  Aristo Pharmaceuticals Pvt.Ltd

• Torvigress 40 MG Tablet

  La Renon

• Tide 100 MG Tablet

  Torrent Pharmaceuticals Ltd

• Tor 20 MG Tablet

  Intas Pharmaceuticals Ltd

• Lhd 5 MG Tablet

  Ipca Laboratories Pvt Ltd.

• Torvel 10 MG Tablet

  Cmr Life Sciences

• Torsinex 5 MG Tablet

  Micro Labs Ltd

• Dytor 40 MG Tablet

  Cipla Ltd

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

This medication belongs to the class loop diuretics. It reduces the blood pressure by inhibiting Na-K-2Cl reabsorption at the ascending loop of Henle. This helps in increasing the excretion of water and sodium.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

test

• Interaction with Alcohol

  Consumption of alcohol is not recommended while you are taking this medicine. It may increase the risk of dizziness and fainting. Avoid performing activities that need mental alertness like operating machinery or driving a vehicle.

• Interaction with Medicine

  • Aminoglycosides: Ototoxicity may be increased.
  • Anticoagulant activity is enhanced.
  • Antidiabetic agents: Glucose tolerance may be decreased.
  • Antihypertensive agents: Effects may be enhanced.
  • Beta-blockers: Plasma concentrations of beta-blockers may be increased with torsemide.
  • Chloral hydrate: Transient diaphoresis, hot flashes, hypertension may occur.
  • Cisplatin: Ototoxicity may be increased.
  • Digitalis: Arrhythmias may occur with diuretic-induced electrolyte disturbances.
  • Enzyme inducers (phenytoin, phenobarbital, carbamazepine) theoretically may reduce efficacy of torsemide.
  • Lithium: Plasma concentrations of lithium may be increased; monitor lithium levels.
  • NSAIDs: Torsemide efficacy may be decreased.
  • Probenecid: Torsemide action may be reduced.
  • Salicylates: Diuretic action may be impaired in patients with cirrhosis and ascites.
  • Thiazides: Synergistic effects may result.

• Interaction with Food

  Information not available.

• Interaction with Disease

  Adjust dose to avoid dehydration. In cirrhosis, avoid electrolyte and acid/base imbalances that might lead to hepatic encephalopathy. Ototoxicity is associated with rapid I.V. administration of other loop diuretics and has been seen with oral torsemide. Do not administer intravenously in less than 2 minutes; single doses should not exceed 200 mg. Hypersensitivity reactions can rarely occur. Monitor fluid status and renal function in an attempt to prevent oliguria, azotemia, and reversible increases in BUN and creatinine. Close medical supervision of aggressive diuresis is required. Monitor closely for electrolyte imbalances particularly hypokalemia and correct when necessary. Coadministration with antihypertensives may increase the risk of hypotension. Use caution in patients with known hypersensitivity to sulfonamides or thiazides (due to possible cross-sensitivity); avoid in patients with history of severe reactions.

• Ques : What is Torsemide?

  Ans : This medication treats edema, that is, it reduces the presence of extra fluid that develops in the body as a result of health problems like kidney or liver disease and heart failure.

• Ques : How long do I need to use Torsemide before I see improvement in my condition?

  Ans : This medication is to be taken till the time you see an improvement in your health conditions.

• Ques : At what frequency do I need to use Torsemide?

  Ans : In the case of patients with edema because of congestive heart failure, the dosage may vary from 10mg -20mg in a day. Those with renal problems may be prescribed about 20mg daily. Patients with hypertension are generally prescribed about 5mg-10mg of the drug to be taken once a day.

• Ques : Should I use Torsemide empty stomach, before food or after food?

  Ans : This medication is mostly prescribed for daily consumption and can be taken before or after food.

• Ques : What are the instructions for the storage and disposal of Torsemide?

  Ans : This medication should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

• Ques : Does Torsemide raise blood sugar?

  Ans : Yes, it may raise blood sugar levels causing hyperglycemia. Hence, it is important to keep track of your blood glucose levels during treatment with Torsemide.

• Ques : What are the side effects of Torsemide?

  Ans : The side effects of Torsemide include headache, dizziness, dehydration, constipation, decreased blood pressure and stomach upset.

• Ques : Does Torsemide increase creatinine?

  Ans : Yes, it may cause a mild increase in creatinine values depending on the dose you are taking. These increased creatinine levels may increase slightly more when this medicine is used for the long term.

• Torasemide- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 11 December 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/torsemide

• Torasemide- DrugBank [Internet]. Drugbank.ca. 2019 [Cited 11 December 2019]. Available from:

  https://www.drugbank.ca/drugs/DB00214

• Torsemide- Drugs, Herbs and Supplements, MedlinePlus, NIH, U.S. National Library of Medicine. [Internet]. medlineplus.gov 2018 [Cited 11 December 2019]. Available from:

  https://medlineplus.gov/druginfo/meds/a601212.html