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Overview

Vasopressin

Prescription vs OTC : Prescription by Doctor required

About Vasopressin

Vasopressin resembles the anti-diuretic hormone, which is generally produced by the pituitary gland of the body. The drug increases water retention in the body, by reducing urine formation. It helps the kidneys to absorb water effectively. Vasopressin effectively increases blood pressure of the body as it narrows blood vessels.

Doctors generally prescribe Vasopressin for the treatment of diabetes insipidus, which occurs when the pituitary gland is not able to secrete the anti-diuretic hormone.

Before you start taking Vasopressin, inform your doctor about any medical conditions that you may suffer from. They include coronary heart disease, asthma, migraine headaches, epilepsy and kidney problems. Pregnant women should only take Vasopressin as per the doctor’s advice. The drug can cause early labour if taken during the final months of the pregnancy.

The drug is generally injected through IV into a vein, or administered into the muscle. The injection is generally given by a doctor or nurse at the hospital or clinic.

Some common side effects of this medicine are stomach cramps, paleness of the skin, sweating, gas and tremor in the hands and feet. Major side effects that one may experience are seizures, stupor, unconsciousness, problems with breathing and irregular heartbeat.

Symptoms of overdose include drowsiness, weight gain, confusion, listlessness, water intoxication. Water intoxication requires withdrawal of the drug; severe intoxication may require osmotic diuresis and loop diuretics.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Nephrologist before using this medicine.

    What are the uses of Vasopressin

    • Central Diabetes Insipidus

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Nephrologist before using this medicine.

    What are the contraindications of Vasopressin ?

    • Hypersensitivity

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Nephrologist before using this medicine.

    What are the side effects of Vasopressin ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Nephrologist before using this medicine.

    Key highlights of Vasopressin

    • Is It safe with alcohol?

      Interaction with alcohol is unknown. Please consult your doctor.

    • Are there any pregnancy warnings?

      Vasopressin may be unsafe to use during pregnancy.
      Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

    • Are there any breast-feeding warnings?

      Unknown. Human and animal studies are not available. Please consult your doctor.

    • Is it safe to drive while on this medicine?

      There is no data available. Please consult doctor before consuming the drug.

    • Does this affect kidney function?

      There is no data available. Please consult doctor before consuming the drug.

    • Does this affect liver function?

      Some patients respond to much lower doses with cirrhosis. Please consult doctor before consuming the drug.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Nephrologist before using this medicine.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      If you miss a dose of Vasopressin, skip it and continue with your normal schedule. Do not double the dose.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Nephrologist before using this medicine.

    Medicines containing Vasopressin

    Below is the list of medicines, which contains Vasopressin as ingredient

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Nephrologist before using this medicine.

    How does this medication work?

    Vasopressin acts upon three different kinds of receptors such as vasopressin receptor V1a, vasopressin receptor V2 and vasopressin receptor V1a. This controls the reabsorption of free water within renal medullar.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Nephrologist before using this medicine.

      What are the interactions of Vasopressin ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Medicine

        • Decreased effect: Lithium, epinephrine, demeclocycline, heparin, and alcohol block antidiuretic activity to varying degrees.
        • Increased effect: Chlorpropamide, phenformin, urea and fludrocortisone potentiate antidiuretic response.
      • Interaction with Disease

        Use with caution in patients with seizure disorders, migraine, asthma, vascular disease, renal disease, cardiac disease; chronic nephritis with nitrogen retention. Goiter with cardiac complications, arteriosclerosis; I.V. infiltration may lead to severe vasoconstriction and localized tissue necrosis; also, gangrene of extremities, tongue, and ischemic colitis. Elderly patients should be cautioned not to increase their fluid intake beyond that sufficient to satisfy their thirst in order to avoid water intoxication and hyponatremia; under experimental conditions, the elderly have shown to have a decreased responsiveness to vasopressin with respect to its effects on water homeostasis.

      References

      • Vasopressin- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2021 [Cited 25 Nov 2021]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/rn/11000-17-2

      • VASOPRESSIN injection- Daily Med [Internet]. dailymed.nlm.nih.gov. 2021 [Cited 25 Nov 2021]. Available from:

        https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7ae1c8c9-7d75-55a8-e053-2991aa0af05b

      • VASOPRESSIN injection, solution- Daily Med [Internet]. dailymed.nlm.nih.gov. 2017 [Cited 25 Nov 2021]. Available from:

        https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=40dab227-b05b-4e72-a59c-6e6f8a80252e

      • Vasopressin- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2021 [Cited 25 Nov 2021]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/rn/11000-17-2

      • VASOPRESSIN injection- Daily Med [Internet]. dailymed.nlm.nih.gov. 2021 [Cited 25 Nov 2021]. Available from:

        https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7ae1c8c9-7d75-55a8-e053-2991aa0af05b

      • VASOSTRICT- vasopressin injection- Daily Med [Internet]. dailymed.nlm.nih.gov. 2020 [Cited 25 Nov 2021]. Available from:

        https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=6672a5c9-bcfd-d7fc-e053-2991aa0aef88

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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