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Overview

Zinetac 150 MG Tablet

Banned
Manufacturer :  Glaxosmithkline Pharmaceuticals Ltd
Medicine Composition :  Ranitidine
Prescription vs OTC : Prescription by Doctor not required

About Zinetac 150 MG Tablet

Zinetac 150 MG Tablet is prescribed as the short-term treatment of active duodenal ulcers and benign gastric ulcers. This medicine is also prescribed for long-term prophylaxis of duodenal ulcer and gastric hypersecretory states, recurrent postoperative ulcer, prevention of acid-aspiration pneumonitis during surgery, and prevention of stress-induced ulcers; causes fewer interactions than cimetidine.

This medicine belongs to a drug group known as histamine (H2) receptor blocker. Zinetac 150 MG Tablet works by reducing the amount of acid produced in the stomach, effectively treating gastroesophageal reflux disease (GERD), Zollinger-Ellison syndrome and upper GI bleeding ulcers.

Patients need to be aware that intake of this medicine can increase the chances of succumbing to pneumonia. Its symptoms are pain in the chest, fever, coughing up slimy green snot and problems with breathing. Also, make sure that you are not allergic to this medication.

Make sure it is safe for you to consume this medication if you suffer from health problems like liver, kidney disease and porphyria. Although this medication does not really harm an unborn child, ensure that you tell your doctor if you are pregnant.

This medicine does pass into breast build, thus let your doctor know if you are taking this medication while breastfeeding too. It should be taken according to instructions given by the doctor. Do not change the dosage on your own.

This medication is meant for oral consumption and should be swallowed immediately. Do not chew or let the effervescent tablet dissolve after you place it in your mouth.

For instance, if you are taking 25 mg of it, dissolve it in 1 teaspoon of water. If you are taking 150 mg of this medicine, it should be dissolved in 6-8oz of water. It should be continued until the ulcer heals completely. Generally, it takes about 8 weeks for an ulcer to properly heal.

Take exactly as directed (at meals and bedtime); do not increase dose - may take several days before you notice relief. If antacids are approved by prescriber, allow 1 hour between antacid and Zinetac 150 MG Tablet.

Avoid OTC medications, especially cold or cough medication and aspirin or anything containing aspirin. Follow the diet as the prescriber recommends.

Symptoms of overdose include muscular tremors, vomiting, rapid respiration, renal failure, CNS depression. Treatment is primarily symptomatic and supportive.

Use with caution in children <12 years of age; use with caution in patients with liver and renal impairment; dosage modification required in patients with renal impairment; long-term therapy may cause vitamin B12 deficiency.

    What are the uses of Zinetac 150 MG Tablet

    • Acidity

    • Peptic Ulcer

    • Heartburn

    • Duodenal Ulcer

    • Gastric Ulcer

    • Hypersecretory Condition

    • Gastroesophageal Reflux Disease

    • Gastrointestinal Bleeding

    • Other Forms Of Ulcers

    What are the contraindications of Zinetac 150 MG Tablet ?

    What are the side effects of Zinetac 150 MG Tablet ?

    Key highlights of Zinetac 150 MG Tablet

    • How long is the duration of effect?

      The duration of the effect of this drug is more than 24 hours.

    • What is the onset of action?

      The onset period of this drug is about 2 to 3 hours after administration.

    • Are there any pregnancy warnings?

      Pregnant women must consult doctor before using this medication.

    • Is it habit forming?

      The drug is not known to have habit forming tendencies.

    • Is It safe with alcohol?

      Consult your doctor before consuming alcohol.

    • Is it safe to drive while on this medicine?

      Although it is considered safe to drive after taking this medicine, but if the patient experiences side effects such as drowsiness, dizziness or feels sleepy after taking the medicine, then it is recommended that they avoid driving or handling any heavy machinery.

    • Is it safe to drive while on this medicine?

      Driving is usually safe if you are taking Zinetac 150 MG Tablet. As this medicine does not affect patients ability to drive.

    • Does this affect kidney function?

      In case of renal impairment, doctor's consultation is a must before its administration. Dosing adjustment in renal impairment:

      • Clcr 10-50 mL/minute: Administer at 75% of normal dose or administer every 18-24 hours.
      • Clcr <10 mL/minute: Administer at 50% of normal dose or administer every 18-24 hours.
      • Hemodialysis: Slightly dialyzable (5% to 20%).

    • Does this affect liver function?

      Patient must consult a doctor before taking this medication in case of liver impairment.

    • Is It safe with alcohol?

      It is suggested not to take Zinetac 150 MG Tablet with alcohol, as it is unsafe to take it concomitantly.

    • Is it safe to drive while on this medicine?

      Driving is usually safe if you are taking Zinetac 150 MG Tablet. As this medicine does not affect patients ability to drive.

    What are the substitutes for Zinetac 150 MG Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Zinetac 150 MG Tablet , and hence can be used as its substitute.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      In case you miss a dose, use it as soon as you notice. If it is close to the time of your next dose, skip the missed dose and resume your dosing schedule. Do not use extra dose to make up for a missed dose.

    • Are there any overdose instructions?

      Consult your doctor in case of overdose.

    How does this medication work?

    This drug acts by inhibiting the action of histamine at specific H2 receptors present in the gastric parietal cells. Thus, gastric acid secretion process is inhibited.

      What are the interactions of Zinetac 150 MG Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Alcohol

        Avoid the consumption of alcohol while taking this medicine. Contact your doctor if you experience prolonged heartburn or presence of blood in the vomit or stools.
      • Interaction with Lab Test

        False-positive urine protein, gastric acid secretion test, skin test allergen extracts, serum creatinine and serum transaminase concentrations, urine protein test might appear. Thus before testing must inform your doctor that you are taking Ranitidine.
      • Interaction with Medicine

        • Ketoconazole : Report the use of either of the medicine to the doctor. The use of this medication tends to make Ketoconazole less effective. Inform the doctor if the symptoms do not improve or worsen. Do not discontinue the use of any medicine without consulting your doctor.
        • Loperamide : Report the use of either of the medicine to the doctor. Dose adjustment and safety monitoring may be needed when both these medicines are taken together. Your doctor may prescribe alternative medicine if your intake of Loperamide is very high or you suffer have a heart condition.
        • Metformin : Report the use of either of the medicine to the doctor. An adjustment in dose and more frequent monitoring of blood level are advised when these two medicines are taken together.
        • Atazanavir : Report the use of either of the medicine to the doctor. Your doctor may adjust the dosage of Atazanavir when it is to be consumed along with this medication. Do not stop the usage of any medication without consulting your doctor.
        • Dasatinib : Report the usage of either of the medications to the doctor. It is advised to replace one or both of these medicines with alternates that do not interact. Do not stop the usage of any medication without consulting the doctor.
        • Pazopanib : Report the use of either of the medicine to the doctor. Use of these two medications together should be avoided. Your doctor may prescribe suitable alternatives in such cases.
        • Decreased toxicity of atropine.
        • Increased toxicity of cyclosporine (increased serum creatinine), gentamicin (neuromuscular blockade), glipizide, glyburide, midazolam (increased concentrations), metoprolol, pentoxifylline, phenytoin, quinidine.
      • Interaction with Disease

        There is not enough data available on negative interactions of this medicine with diseases. Please consult your doctor and inform him about your medical conditions and history before taking this medicine.

        • Gastrointestinal Bleeding: Use of this medication is not recommended for use if any symptoms indicating gastrointestinal bleeding exists. Consult your doctor if there is blood in vomit or the stools are bloody or black.
        • Porphyria: This medication should be used with extreme caution in patients having a history of acute Porphyria.

      FAQs about Zinetac 150 MG Tablet

      • Ques : What is Zinetac 150 mg tablet?

        Ans : Zinetac belongs to a drug group known as a histamine-2 blocker. It is used to reduce the amount of acid produced in the stomach. This medication also treats stomach acid-related disorders such as heartburn and acid reflux disease. It contains Ranitidine as a working constituent.

      • Ques : What is the use of Zinetac 150 mg tablet?

        Ans : Zinetac is used for the treatment and prevention from conditions and symptoms of diseases like a duodenal ulcer, gastric ulcer and gastroesophageal reflux disease (GERD).

      • Ques : What are the side effects of Zinetac 150 mg tablet?

        Ans : Side effects include headache, sleepiness, tiredness, constipation, etc.

      • Ques : Can Zinetac be used to treat gastritis?

        Ans : Yes, It can be used for the short-term treatment of gastritis. It works by curbing the amount of acid discharged into the stomach and diminishing stomach pain and acid reflux. The patient should consult a doctor for its further uses and side effects and should inform the doctor about any ongoing medications and treatment before using to avoid undesirable effects.

      • Ques : How long do I need to use zinetac tablet before I see improvement of my conditions?

        Ans : This medication should be consumed, till the complete eradication of disease. Thus it is advised to use, till the time directed by your doctor and moreover taking this medication longer than it was prescribed, can also cause inadequate effect on the patient. So please consult your doctor.

      • Ques : At what frequency do I need to use zinetac medicine?

        Ans : The duration of effect for this medicine is dependent on the severity of the patient’s condition. Therefore the frequency of consumption of this medication will vary from person to person, it is advised to follow proper prescription of the doctor, directed according to the condition.

      • Ques : Should I use zinetac tablet empty stomach, before food or after food?

        Ans : This medication is commonly taken orally from mouth and the action of salts involved in this medication, do not depend on using it pre-meal or post-meal. It is advised to consult a doctor before use and take it at a fixed time in a day.

      • Ques : What are the instructions for storage and disposal of tablet?

        Ans : This medication contains salts, which are suitable to store at room temperature and keeping this medication above or below that, can cause an inadequate effect. Protect it from moisture and light. Keep this medication, away from the reach of children. It is advised to dispose the expired or unused medication, for avoiding its inadequate effect.

      References

      • Ranitidine- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 25 April 2019]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/rn/66357-35-5

      • Zantac Tablets 150mg- EMC [Internet]. www.medicines.org.uk. 2015 [Cited 25 April 2019]. Available from:

        https://www.medicines.org.uk/emc/product/219/smpc

      • Ranitidine: Uses, Side effects, Dosage- Drugs Bank [Internet]. drugsbanks.com. 2017 [Cited 25 April 2019]. Available from:

        https://www.drugsbanks.com/ranitidine/

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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      Reviewed ByDr. Yuvraj Arora MongaMD-Pharmacology, MBBSSexology
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