Ige deficiency is difficult to define because normal ige concentrations are so low.
Immunoglobulin deficiency can be defined as ige levels less than 2 u/ml in children and less than 4 u/ml in adults.
Current guidelines state that the goal of haart is to suppress and maintain vl below detectable levels (<50 copies/ml). Despite being on a potent antiretroviral (arv) regimen, some patients experience persistent detectable viremia above the limit of detection of the
assay, which may be considered an indicator of virologic failure.