Total Iron Binding Capacity (TIBC) is a blood test to determine the iron status of the blood. Iron binds to a protein called transferrin and is then carried throughout the blood. TIBC test is commonly done along with a serum iron test. These tests help in the diagnosis of iron deficiency or iron overload. In anaemic patients, the test is used to determine the cause of the condition, whether it is due to iron deficiency or other causes like chronic blood loss and illness. In case of iron poisoning, this test can be used to screen for hemochromatosis which is a hereditary condition associated with excessive iron accumulation.