Hepatitis B Core Antigen Total, also known as Anti-HBc, HBcAb Total test; is a blood test to detect acute and chronic Hepatitis B virus infections. The tests look for different signs of infection such as the Antigens, made by the viruses; Antibodies, made by the body to fight the infection; and Hepatitis B DNA, which is the genes of the virus and confirms its presence. The test detects both Hepatitis antibodies IgM and IgG,, and Hepatitis B core antigen. Those who had Hepatitis B vaccine will not have the core antibody in their blood.