Purine metabolism has an end product called the uric acid. The increased level of uric acid in the urine indicates an increased plasma uric acid level. Active tubular secretion means uric acid is filtered by the glomeruli present in the body and is reabsorbed by the tubules. It is essential to keep the urine uric acid under control it reflects the amount of dietary purine and other endogenous nucleic acid breakdowns.
A 24- hour urine-uric-acid test is often suggested for collection to measure and interpret the urinary analysis. However, random collections for the urine-uric-acid test are conducted when there is a suspected an acute renal failure secondary to uric acid is there. The test is advisable for small children or patients who cannot collect a 24-hour specimen. Therefore all that a urine-uric-acid-random test does is to measure the uric acid in the urine. The acid is produced during the digestion of some foods that affect the natural breakdown of cells in the body. The test is recommended when the doctor finds symptoms that could be the reason for high uric acid levels.
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