Methylcobalamin

Methylcobalamin or in general term Vitamin B-12. This medication is used by people of all ages suffering from a gut disease where they are unable to completely absorb and use the vitamin or this medication and may be at risk of vitamin B-12 deficiency.

It is one of the most important nutrients required in the human body. A lack of this vitamin can cause severe and permanent neurological damage. The medicine also treats Pernicious anaemia with weakness, numbness, tingling of fingers, etc.

It plays a key role in the functioning of the Brain and Nervous system and the formation of the Red Blood Cells. Also, it is responsible for the protection and regeneration of Neurons. This medicine also fights against the degenerative cell condition called Multiple sclerosis. It acts as a stress reliever for the body and mind.

There exists evidence that people, particularly elderly whose serum cobalamin concentrations <300 pg/mL, should receive replacement parenteral therapy; this recommendation is based upon neuropsychiatric disorders and cardiovascular disorders associated with lower sodium cobalamin concentrations.

Vitamin B12 deficiency for >3 months results in irreversible degenerative CNS lesions; treatment of vitamin B12 megaloblastic anemia may result in severe hypokalemia, sometimes, fatal, when anemia corrects due to cellular potassium requirements.

B12 deficiency masks signs of polycythemia vera; vegetarian diets may result in B12 deficiency; pernicious anemia occurs more often in gastric carcinoma than in general population.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Dietitian/Nutritionist before using this medicine.

• Fatigue

• Amyotrophic Lateral Sclerosis (Als)

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Dietitian/Nutritionist before using this medicine.

• Allergy

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Dietitian/Nutritionist before using this medicine.

• Restlessness

• Diabetic Neuropathy

• Dizziness

• Fatigue

• Injection Site Bruising

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Dietitian/Nutritionist before using this medicine.

• How long is the duration of effect?

  The peak of the effect can be observed within 3 hours after consumption. Effects can be felt within half an hour after intake.

• What is the onset of action?

  The onset of action is seen or felt within half and hour of consumption.

• Are there any pregnancy warnings?

  Yes, It is safe to consume this medication when pregnant.

• Is it habit forming?

  No, it is not habit forming but it should not be consumed in excess.

• Are there any breast-feeding warnings?

  It is shown that the supplement is passed on through milk while breast-feeding. Hence it is not recommenced while breast feeding.

• Is It safe with alcohol?

  Alcohol decreases the level of vitamin b in the body, hence the consumption of alcohol is not recommend while taking this supplement.

• Is it safe to drive while on this medicine?

  Yes, it is safe to drive after consumption of this medication.

• Does this affect kidney function?

  Excess consumption is know to damage the kidneys.

• Does this affect liver function?

  Excess consumption is not recommended if the person suffer from liver diseases.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Dietitian/Nutritionist before using this medicine.

• Are there any missed dose instructions?

  Try not to miss the dose, you need not take a double dose incase you have missed the previous one.

• Are there any overdose instructions?

  In case of overdose consult a doctor.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Dietitian/Nutritionist before using this medicine.

• India

• United States

• Japan

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Dietitian/Nutritionist before using this medicine.

Below is the list of medicines, which contains Methylcobalamin as ingredient

• Unicobal 500 MCG Injection

  Unichem Laboratories Ltd

• Nuroday 1500 MCG Tablet

  Wockhardt Ltd

• Methycobal 500 MCG Tablet

  Wockhardt Ltd

• Alnuro 500 MCG Injection

  Mankind Pharmaceuticals Ltd

• Nurokind Od 1500 MCG Injection

  Mankind Pharmaceuticals Ltd

• Methycobal 500 MG Tablet

  Wockhardt Ltd

• Mbson Sl 1500 MCG Tablet

  Unison Pharmaceuticals

• Mecoba 500 MCG Tablet

  Abbott Healthcare Pvt. Ltd

• Mecovit 500 MG Tablet

  Cipla Ltd

• Nurokind 500 MCG Tablet

  Mankind Pharmaceuticals Ltd

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Dietitian/Nutritionist before using this medicine.

This medication helps in transferring methyl groups to homocysteine for regenerating methionine by acting as a cofactor for the enzyme responsible for this work, methionine synthase. In anaemic condition, it promotes the synthesis of nucleic acid in bone marrow, which leads to an increase in the production of blood cells. It also promotes maturation and division of erythrocytes.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Dietitian/Nutritionist before using this medicine.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  It decreases the effectiveness of medication.

• Interaction with Medicine

  Some medication that have a serious interaction with Methylcobalamin are Leukeran ( chlorambucil ), Prilosec( omeprazole), colcrys and Mitigare and the herbal supplement goldenseal.

• Interaction with Food

  Since it’s derived from food sources there is no severe reaction with food.

• Interaction with Disease

  Vitamin B12 does not interact with diseases.

• Ques : What is Methylcobalamin?

  Ans : This drug, also known as Vitamin B-12 is used by people of all ages suffering from a gut disease where they are unable to completely absorb and use the vitamin or this medication and may be at risk of vitamin B-12 deficiency.

• Ques : How long do I need to use Methylcobalamin before I see improvement in my condition?

  Ans : This medication should be consumed, until the complete eradication of the disease. Thus it is advised to use, till the time directed by your doctor. Also taking this medication longer than it was prescribed, can cause an inadequate effect on the patient's condition.

• Ques : At what frequency do I need to use Methylcobalamin?

  Ans : The duration of effect for this medicine is dependent on the severity of the patient’s condition. Therefore the frequency of usage of this medication will vary from person to person. It is advised to follow the proper prescription of the doctor, directed according to the patient's condition.

• Ques : Should I use Methylcobalamin empty stomach, before food or after food?

  Ans : This medication is advised to be consumed orally. The salts involved in this medication react properly if it is taken after having food. If you take it on an empty stomach, it might upset the stomach. Please consult the doctor before using it.

• Ques : What are the instructions for the storage and disposal of Methylcobalamin?

  Ans : This medication contains salts which are suitable to store only at room temperature, as keeping this medication above or below that, can cause an inadequate effect. Protect it from moisture and light. Keep this medication away from the reach of children.

• Ques : Why can’t I get sufficient vitamin B12 (Methylcobalamin) from my diet?

  Ans : Best B12 sources are meat, fish, eggs and dairy products. People who are vegetarian or vegan may suffer from lack of vit B12 as it is not found naturally in foods such as fruits, vegetables and grains. Therefore, deficiency of Vitamin B12 is usually noticed in vegetarians or vegans.

• Ques : What happens if I have vitamin B12 (Methylcobalamin) deficiency?

  Ans : Deficiency of vitamin B12 causes tiredness, weakness, constipation, loss of appetite, weight loss, and megaloblastic anemia, etc.

• Ques : How should Methylcobalamin be taken?

  Ans : This drug should be taken in the dose and duration advised by your doctor. It can be taken with or without food. However, it would be best to take it at the same time each day to avoid the chances of missing a dose.

• Ques : What if I forget to take a dose of Methylcobalamin?

  Ans : If you forget a dose of this drug, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose, and take the next scheduled dose in the prescribed time.

• Ques : Is Methylcobalamin safe?

  Ans : Yes, it is totally safe to be consumed. It is advised to follow the doctor’s instructions.

• Methylcobalamin-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 26 May 2022].Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/methylcobalamin

• Methylcobalamin-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 26 May 2022].Available from:

  https://go.drugbank.com/drugs/DB03614

• METHYLCOBALAMIN Tablet,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 26 May 2022].Available from:

  https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=METHYLCOBALAMIN