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Overview

Nortipan 75 Mg/10 Mg Tablet

Manufacturer :  Medley Pharmaceuticals
Medicine Composition :  Pregabalin, Nortriptyline
Prescription vs OTC : Prescription by Doctor not required

About Nortipan 75 Mg/10 Mg Tablet

Nortipan 75 Mg/10 Mg Tablet is a combination medication prescribed for the treatment of severe neuropathic pain. It is also used for the management of neuropathic disorders like diabetic peripheral neuropathy, postherpetic neuralgia, and spinal cord injury.

It works by binding to a certain region of the brain and reducing the pain signals sent out by the damaged nerves of the body. This medicine is also utilised for treating restless leg syndrome, epilepsy, shingles, seizures, fibromyalgia and generalised anxiety disorder.

This medication is not recommended for you if you are pregnant, or have an allergic reaction towards any of its ingredients. Some medicines interact with it. Inform your doctor if you are taking any of the following:

  • Angiotensin- converting enzyme inhibitors
  • Benzodiazepines or narcotic pain medicines
  • Thiazolidinedione antidiabetic agents

Ensure your doctor is informed if you have any of the following medical conditions before starting the medication:

  • If you have congestive heart failure, irregular heartbeat, diabetes, bleeding problems, muscle problems, highballed pressure or low platelet count.
  • If you have improper kidney functioning or are on dialysis.
  • If you have a history of angioedema.
  • If you are pregnant, planning to be pregnant or are breastfeeding.
  • If you take any other medicines, dietary supplements or herbal preparations.
  • If you have mental or mood problems, suicidal thoughts, or are dealing with depression.

The dose for this medication may vary according to the age, sex, pathological conditions and other factors. The dosage can later be increased depending on efficacy and tolerability of the patient.

    What are the uses of Nortipan 75 Mg/10 Mg Tablet

    • Neuropathic Pain

    • Diabetic Peripheral Neuropathy

    • Postherpetic Neuralgia

    What are the contraindications of Nortipan 75 Mg/10 Mg Tablet ?

    What are the side effects of Nortipan 75 Mg/10 Mg Tablet ?

    Key highlights of Nortipan 75 Mg/10 Mg Tablet

    • How long is the duration of effect?

      The effect of this medicine lasts for an average duration of 10-12 hours.

    • What is the onset of action?

      This medicine has a varying onset time depending on the intended use.

    • Are there any pregnancy warnings?

      Use of this medicine during pregnancy is not recommended unless absolutely necessary.

    • Is it habit forming?

      This medicine has a low abuse potential with limited physical and psychological dependence.

    • Are there any breast-feeding warnings?

      The medicine is suggested to be ignored by breastfeeding mothers as there is a possibility of side-effects on infant.

    What are the substitutes for Nortipan 75 Mg/10 Mg Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Nortipan 75 Mg/10 Mg Tablet , and hence can be used as its substitute.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      Take the missed dose as soon as you remember.

    • Are there any overdose instructions?

      In case of an overdose, doctor should be consulted immediately.

    How does this medication work?

    This medication is a combination of Pregabalin and Nortriptyline, thus work through a dual mechanism of action. Primarily, it behaves as a GABA analogue and binds to the voltage-gated calcium channels in the central nervous system. This causes a reduced release of neurotransmitters like serotonin, dopamine, substance P thus slowing down nerve signals. Secondarily, it blocks the serotonin reuptake at the neuronal membrane. Also, it inhibits the reuptake of norepinephrine and raises its concentration in the synaptic cleft.

      What are the interactions of Nortipan 75 Mg/10 Mg Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Alcohol

        Alcohol

        Consult your doctor before consuming alcohol.
      • Interaction with Medicine

        Medicine

        This medication reacts with cimetidine, clonidine, diltiazem, fluconazole, fluoxetine, lorazepam, nabilone and oxycodone.

      FAQs about Nortipan 75 Mg/10 Mg Tablet

      • Ques : What is Nortipan 75 Mg/10 Mg Tablet?

        Ans : This medication is a combination of Pregabalin and Nortriptyline and is considered to be the first-line of treatment for neurotic pain, shingles, seizures and fibromyalgia.

      • Ques : How long do I need to use Nortipan 75 Mg/10 Mg Tablet before I see improvement in my condition?

        Ans : This medication is to be taken till the time you see an improvement in your health conditions.

      • Ques : What are the Side Effects of Nortipan 75 mg 10 mg tablet?

        Ans : Possible side-effects include constipation, a decrease in sexual interest, difficulty in passing stool, drowsiness, and sleepiness.

      • Ques : What are the instructions for storage and disposal Nortipan 75 mg 10 mg tablet?

        Ans : Nortipan 75 Mg/10 Mg should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets.

      • Ques : What are the contraindications to Nortipan 75 Mg/10 Mg Tablet?

        Ans : The medicine should not be used if you have the following conditions such as Diabetes mellitus, Epilepsy, Hypersensitivity, Hyperthyroidism, Hypomania, Lactation, Liver disease, Narrow-angle glaucoma, Peripheral edema, etc.

      • Ques : Is Nortipan 75 Mg/10 Mg Tablet safe to use when pregnant?

        Ans : This medication is not recommended for use in pregnant women unless absolutely necessary.

      • Ques : Will Nortipan 75 Mg/10 Mg Tablet be more effective if taken in more than the recommended dose?

        Ans : No, taking higher than the recommended dose can lead to increased chances of side effects.

      • Ques : At what frequency do I need to use Nortipan 75 Mg/10 Mg Tablet?

        Ans : This medication should be taken in the dosage as prescribed by the doctor.

      References

      • Nortriptyline- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 23 January 2020]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/pregabalin

      • Pregabalin- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 23 January 2020]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/nortriptyline

      • Nortriptyline 10 mg Film-coated Tablets [Internet]. medicines.org.uk 2019 [Cited 23 January 2020]. Available from:

        https://www.medicines.org.uk/emc/medicine/32962

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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