Pregalex-M Capsule

This medicine is a combination of methylcobalamin along with pregabalin in combination. Methylcobalamin or in general term Vitamin B-12. It is one of the most important nutrients required in the human body and is the active constituent in this medication. A lack of this vitamin can cause severe and permanent neurological damage. The other active constituent is Pregalin, which is an anticonvulsant and is considered to be the first-line of treatment for neurotic pain, shingles, seizures and fibromyalgia. It is used for the treatment of diabetic nerve pain, epilepsy, spinal cord injury, restless leg syndrome and generalised anxiety disorder. It works by binding to a certain region of the brain and reducing the pain signals sent out by the damaged nerves of the body.

It plays a key role in the functioning of the Brain and Nervous system and in the formation of the Red Blood Cells, other than this, it is responsible for the protection and regeneration of Neurons. Lack of this vitamin causes depression (the reasons not clear why). The drug comes into use when you have low levels of Vitamin B12 in your body, which causes you to Feel Weak, Fatigued and experience slow thinking. This condition is called Pernicious Anaemia. Low level of Folic Acid and Vitamin B12 go hand in hand. This is an active form of Vitamin B12 which is easier for the body to absorb. Though found naturally in meat, fish, eggs and dairy products. The supplement is given to people suffering from low levels of this Vitamin.

• Peripheral Neuropathy

• Decreased Potassium Level In Blood

• Allergy

• Abdominal Pain

• Nausea Or Vomiting

• Skin Rash

• Dizziness

• Sleepiness

• Uncoordinated Body Movements

• Tiredness

• How long is the duration of effect?

  The peak of the effect can be observed within 3 hours after consumption. The effects can be felt within half an hour after intake.

• What is the onset of action?

  The onset of action is seen or felt within half and hour of consumption.

• Are there any pregnancy warnings?

  Yes, It is safe to consume this drug when pregnant.

• Is it habit forming?

  No, it is not habit forming but it should not be consumed in excess.

• Are there any breast-feeding warnings?

  It is shown that the supplement is passed on through milk while breast-feeding. Hence it is not recommenced while breast feeding.

• Is It safe with alcohol?

  Alcohol decreases the level of vitamin b in the body, hence the consumption of alcohol is not recommend while taking this supplement.

• Is it safe to drive while on this medicine?

  Yes, it is safe to drive after consumption of the medicine.

• Does this affect kidney function?

  Excess consumption is know to damage the kidneys.

• Does this affect liver function?

  Excess consumption is not recommended if the person suffer from liver diseases.

Below is the list of medicines, which have the same composition, strength and form as Pregalex-M Capsule , and hence can be used as its substitute.

• Nuromark 750 Mcg/75 Mg Tablet

  Unimarck Healthcare Ltd

• Doloneuron PG 75mg Capsule

  Pulse Pharmaceuticals

• Dewfit Capsule

  Dew Drops Lab

• Altranerv Capsule

  Aaltramed Healthcare Ltd

• Pregard M Capsule

  Organic Laboratories

• M Strong Pg Tablet

  Lloyd Healthcare Pvt Ltd

• Odyna P 750Mcg/75Mg Capsule

  MVD Pharmaceuticals Pvt Ltd

• Vitexid P 750Mcg/75Mg Capsule

  Maneesh Pharmaceuticals Ltd

• Gabamax 750 Mcg/75 Mg Capsule

  Aristo Pharmaceuticals Pvt Ltd

• Methynxt 750Mcg/75Mg Capsule

  Hamps India Pvt Ltd

• Are there any missed dose instructions?

  Try not to miss the dose, you need not take a double dose incase you have missed the previous one.

• Are there any overdose instructions?

  In case of overdose consult a doctor. The symptoms include nausea and uneasy stomach.

Pregalex-M Capsule acts as a cofactor for enzyme methionine synthase, which transfers methyl groups for the regeneration of methionine from homocysteine. In anemia, it increases blood cell production by promoting nucleic acid synthesis in the bone marrow and by promoting maturation and division of erythrocytes. It also binds to the voltage-gated calcium channels in the central nervous system. This causes a reduced release of neurotransmitters like serotonin, dopamine, substance P thus slowing down nerve signals.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  Alcohol

  It decreases the effectiveness of medication.

• Interaction with Medicine

  Medicine

  Some medication that have a serious interaction with Methylcobalamin are Leukeran ( chlorambucil ), Prilosec( omeprazole), colcrys and Mitigare and the herbal supplement goldenseal.

• Interaction with Food

  Food

  Since it’s derived from food sources there is no severe reaction with food.

• Interaction with Disease

  Disease

  Vitamin B12 does not interact with diseases.