Proteins are required for various processes in growth, development and overall health. The main classes of proteins found in the blood are Albumin and Globulin. Albumin makes up almost 60% of the proteins present in the blood. Produced by the liver, it is primarily responsible for tissue metabolism. Metabolism is the use of energy. Globulin makes up the remaining 40% of proteins in blood. Globulins are responsible for making numerous enzymes, antibodies and hormones. As observed, since the amount of Albumins is generally greater than that of Globulins, the ratio of A:G will normally be a little over 1. This serves as a good reference to check for the protein count in blood to diagnose any abnormalities.