About: The Cold Agglutinins Blood Test is conducted to measure the level of cold agglutinins in the blood. Cold agglutinins are antibodies that damage red blood cells by causing them to combine together during low temperatures. They are produced by the immune system and often cause anaemia. And Anaemia can lead to several health issues. A very high concentration of cold agglutinins causes a kind of numbness in your body. As the red blood cells begin to get destroyed, the flow of blood to fingers and toes may stop. This is often the case in people who are suffering from pneumonia. Hence a Cold Agglutinins Test is needed to monitor the presence of this autoantibody drug in the body.