Lp-PLA2-PLAC-Cardiac-Risk-Marker is a test used in measuring the amount of lipoprotein associated phospholipase (Lp-PLA2) in blood. Lp-PLA2 is an enzyme associated with low- density lipoprotein (LDL). Lp-PLA2 is carried to the coronary artery walls by LDL, where it causes an inflammatory response. This condition will cause plaque if present more prone to rupture as the Lp-PLA2 enzyme is known to cause inflammation of coronary artery walls. Hence, high levels of Lp-PLA2 will indicate an increased risk of heart attack or stroke. As a result, PLAC Test, which measures the levels of Lp-PLA2, is considered as a specific independent coronary marker.