AChR Antibodies Test

Muscle tissues have receptors called Acetylcholine receptors (AChR), that bind to neurotransmitter Acetylcholine. This enables control over muscles, particularly voluntary muscles. Myasthenia Gravis (MG) is an autoimmune disorder where the immune system produces AChR antibodies. These antibodies prevent Acetylcholine from binding to the receptors on the muscles. As a result, the patient is unable to exercise control over his muscles. Symptoms include droopy eyelid, double vision, chewing difficulty and muscle weakness. A blood test is done to look for presence of these antibodies in the blood stream of a patient with MG symptoms.

No special preparation is needed. Inform the doctor of any medications being taken by the patient. It is recommended that the patient wears a short sleeved shirt.

The blood sample will be analyzed for the presence of AChR antibodies. AChR antibodies present can indicate: Myasthenia Gravis Thymoma Small cell lung cancers Liver disease AChR antibodies if absent , will enable the doctor to allocate further tests to the patient.

The blood sample will be drawn from a vein on the patient's arm. The site will be cleaned with an alcohol swab. A sterile needle will be inserted into the patient's arm. About 2ml blood will be drawn. The site will be cleaned with a cotton swab.