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Overview

Anti Centromere Antibodies Test

Anti Centromere Antibodies Test

also known as: Antinuclear Antibodies (ANA)

Anti-centromere antibody is a protein which is produced by immune system that mistakenly targets the body's own tissue. These autoantibodies are specific to centromere and kinetochore function. These are affiliated to the definite form of systemic sclerosis, and can be detachable in variable proportion of SS patients. ACA occur frequently in the limited systemic scleroderma and irregularly in the diffuse form of scleroderma. These antibodies will be seen rare in healthy persons. When a decreased likeness of aggressive internal organ involvement, such as fibrosis is noticed then these antibodies are present in the early stages of this disease. Nearly in 60% of patients with limited systemic scleroderma and 15% of those with diffuse form of scleroderma this antibodies are found. Anti-centromere test is done to differentiate between systemic scleroderma and diffuse form of scleroderma with similar symptoms.

The Anti-Centromere Antibodies are used in the test to help the diagnosis of autoimmune disorders which is a form of systemic scleroderma. This systemic scleroderma is a CREST syndrome. ACA test is generally used by a health practitioner who has the additional information about the later stages when the ACA is positive. The patient needs to be kept in a mere confidence on the condition of his/her health on/before/after the tests. Neatly cleaned cloth must be used at the test environment and there should be very clear equipments and ambiance while the tests are being held.

This ACA test may be useful to check the symptoms of the patients in harmony with systemic sclerosis including skin involvement and arthralgias. This test is done to aid the diagnosis of calcinosis, Raynaud phenomenon, esophageal dysfunction, sclerodactyly, and telangiectasia (CREST) syndrome. When you want to confirm or exclude the diagnosis of systemic rheumatic disease, this test may be useful. Anti-centromere antibodies can be determined using this test.

Similar to any other blood test, the ANA is also a mere blood test where 5-10 ml of blood is collected through a broad needle and kept in a tube container. A nominal room temperature has to be maintained at the test area so that the results have no environmental impacts. The collected blood sample needs to be separated in two-three separate tube containers where a series of tests are conducted using different catalysts like the Scl-70 (anti-topoisomerase) test. The extracted blood sample must be neatly shipped by covering the opening of the Tube container where the extract is stored.

Specimen
Serum
Volume
1 mL
Container
Red-top tube or gel-barrier tube.
Type Gender Age-Group Value
Anti Centromere Antibodies
Unisex
All age groups
Normally, the antibodies are absent. They are detected in case of Autoimmune conditions
Average price range of the test is between Rs.1700 to Rs.3000 depending on the factors of city, quality and availablity.

Table of Content

What is Anti Centromere Antibodies Test?
Preparation for Anti Centromere Antibodies Test
Uses of Anti Centromere Antibodies Test
Procedure for Anti Centromere Antibodies Test
Specimen Requirements
Normal values for Anti Centromere Antibodies Test
Price for Anti Centromere Antibodies Test
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Popular Questions & Answers

In my face More pimples and dark spots, I am Using Dabur Rose Water Daily 2-3 times, is Any Problem?

BHMS, PGDEMS
Homeopathy Doctor, Satara
In my face More pimples and dark spots, I am Using Dabur Rose Water Daily 2-3 times, is Any Problem?
Please check if your skin is becoming oily after use of gulabari then stop the use. Take proper home care with Anti acne face wash, look for nutritious diet. Take plenty of water.
4 people found this helpful

I have no child after my 4 years married life. I am under treatment since 2 yrs. The report of my anti mullerian hormone test is 1.27 NG/ML. Doctor told me that the egg quality is very low which affects for getting pregnant. Kindly advise me.

MD - Obstetrtics & Gynaecology, Fellowship in Infertility
IVF Specialist, Noida
I have no child after my 4 years married life. I am under treatment since 2 yrs. The report of my anti mullerian horm...
Hi. AMH of 2- 4 ng/ ml is optimum .However, this alone is not sufficient to arrive at a conclusion regarding the fertility status. We always co relate it with an ultrasound. Moreover. It is the egg number that can be commented upon and there is no test in the lab for egg quality except to see the fertilisation rate. Therefore. Kindly get ultrasound done too.
5 people found this helpful

Sir am getting full on itching sensation on my both hands and legs. On hands am having small small fungus type and allergy type area! Kindly suggest me.

BHMS
Homeopath, Chennai
Sir am getting full on itching sensation on my both hands and legs. On hands am having small small fungus type and al...
In Allopathy, anti-histaminics or immunosuppressant medicines like steroids are used which only give temporary relief, with the problem returning once the medicine is stopped. On the other hand, during Homeopathy treatment of allergy is cured by strengthening the immune system and the symptoms subside on their own. At the same time, it needs to be understood that this is purely natural allergy treatment. No steroids or anti allergic medicines are used. The immunity is strengthened by Homeopathy instead of being suppressed as happens with allopathic treatment. You can easily take an online consultation for further treatment guidance and permanent cure without any side effects
1 person found this helpful

I'm having red acne all over my face. I'm not understanding the root cause and how to treat it.

MBBS
General Physician, Hyderabad
I'm having red acne all over my face.
I'm not understanding the root cause and how to treat it.
It's due to hormonal changes ,avoid oily food and regular cleanliness and anti - acne face wash, apply natural alovera gel ,and share if your using any medications.

Popular Health Tips

Cervical Spondylosis (Arthritis of the Neck) - Know Its Treatment!!

BPTh/BPT, MPT - Orthopedic Physiotherapy
Physiotherapist, Gurgaon
Cervical Spondylosis (Arthritis of the Neck) - Know Its Treatment!!

Cervical spondylosis is fast becoming the bane of modern life. An age-related wear and tear problem affecting the spinal discs in your neck, cervical spondylosis is increasingly affecting the young because of the use of cell phones, laptops and the like.

Cervical spondylosis is a general term used to define shrinkage of discs in between vertebrae in the neck region. Along with disc degeneration, bony projections also form in the area and are called bone spurs.
Other causes of cervical spondylosis are dehydrated discs. Discs are thick, pad-like cushions in between vertebrae that act as shock absorbers. They are made of a gel- like material that can dry over time. This causes the spinal vertebrae to rub together causing pain. The discs also crack which allows the internal gel-like material to spill out and impinge on spinal nerves causing symptoms.

There is a narrowing of the space required by the spinal cord and nerves that emanate in the upper spine to go to various parts of the body. Pinching of these nerves can cause alarming symptoms like:

  1. Numbness and weakness in your arms, hands, legs and feet
  2. Lack of coordination and difficulty in walking
  3. Loss of bladder or bowel movement
  4. Stiffness and pain in neck

Treatment and management
Usually, cervical spondylosis doesn’t cause any symptoms. But when you start experiencing pain, stiffness and weakness of muscles, it’s best to go to a doctor who will diagnose the problem and then treat it.
Treatment for cervical spondylosis depends on the severity of your symptoms. Its goal is to get rid of pain, allow you to carry on your daily activities and prevent any permanent damage to your spinal cord and nerves.

Medicines

  1. Anti-inflammatory drugs are prescribed to reduce pain and inflammation. Example Ibuprofen.
  2. Corticosteroids are oral medications to get rid of the severe pain. If these don’t work, your doctor can suggest steroid injections.
  3. Muscle relaxants medicines relax the muscles in the upper part of the spine and help in curing neck pain and stiffness
  4. Anti-seizure medications are also prescribed to dull the pain of damaged nerves in the spine. These include epilepsy medications, such as gabapentin and pregabalin.

Physiotherapy

  1. Non surgical treatments are usually very effective in treating cervical spondylosis and surgery is usually not required. Physiotherapy is a bulwark for patients as it helps manage the condition very well.
  2. Neck exercises that help stretch and strengthen muscles in your neck and shoulders can help manage debilitating symptoms of cervical spondylosis.
  3. Few patients also benefit from traction, which can help provide more space for nerve roots within the spine.

Surgery

  1. Surgery is the last resort for treating cervical spondylosis.
  2. It is suggested when non-surgical treatments fail and the pain and neurological signs such as weakness in your arms or legs get worse.
  3. It is done to create more room for your spinal cord and nerve roots.

Cervical spondylosis surgery typically involves removing:

  1. Herniated disk
  2. Bone spurs
  3. Part of a vertebra. 

If you wish to discuss about any specific problem, you can consult a Physiotherapist.

3458 people found this helpful

Tips For Monsoon!

BHMS
Homeopathy Doctor, Bahadurgarh
Tips For Monsoon!

Monsoon is the season that brings happiness to our life as it makes the environment cool after the hot and scorching sun rays during the summer. But, even after having the cool splash of monsoon rain, there are some flaws and negative effects from which you need to protect yourself.  There are certain health risks that are brought by monsoon from which people needs to be really careful. If you have kids and elderly people at home, they will be really susceptible and are affected with the health conditions like allergies, cough, cold etc.  Even when you are having your diet, it will be really important to be cautious about meal and choose the adequate type of meal that won’t make you sick.

The first water droplets of the monsoon make us relieved and joyous. This season can be a remedy of rashes we got due to prickly heat during the summer. But, we too need to be really careful during monsoon with regards to the food we intake and the activities we perform.  There are certain health risks we can suffer due to monsoon. Especially kids are very susceptible during monsoon. This is the season where waterborne bacteria can attack us and we can get reduction in our immunity level. Normally people suffer from indigestion, allergies and several types of infections. Let us find out some tips that will keep us healthy during monsoon.

Be healthy throughout the monsoon season in India needs particular care to be taken. The rainfall and water lying around makes it very simple for mosquitoes to type and rises the risk of mosquito conveyed infections, such as malaria and dengue high temperature with fever. Viral infections are also spread easily during the monsoon season.

Tips stay healthy in monsoon season

  • If desired to eat road side food, the rainy season isn’t the time to indulge. water and raw vegetables is  are not hygienic during  the monsoon.
  • Use a powerful insect repellent to hold mosquitoes away and prevent getting bitten. It’s furthermore good concept to take anti-malarial drug during this monsoon.
  • Where likely, try to avoid walking through rainy water. It can lead to numerous fungal diseases of the feet and heels.
  • Keep the items like Umbrella, rain coat etc when you are going out.
  • Take moderately hot food and drinks in this monsoon.
  • Keep away the children to play in the rain and rainy water.
  • Also avoid walking where water is lying on the street, as traffic will propel by and spray it all over you.
  • Dry your feet when they get wet.
  • Avoid colds and coughs by keeping your body moderately hot and dry.
  • Don’t go in air conditioned rooms with wet hair and damp apparels.
  • If you suffer from asthma or diabetes, avoid residing any place with wet walls. It encourages the development of fungus and can be especially hurtful.
  • Drink many of heating herbal teas, particularly those with antibacterial properties.

Choice of diet during monsoon

During the monsoon season, it is advised not to consume fast food and the snacks from the roadside stalls. This can give rise to stomach infection.  Most of the time people suffer from the problem of indigestion during the monsoon season as the airborne bacteria are very well active in the environment and can easily get inside your body with the food you eat.  Since during the monsoon season, humidity is really high in the environment, the ability of body to digest comes down. It will be better for people to avoid the oily food which are prepared in street. Only the healthy food prepared at home must be considered.

1. Fruits

It is really essential for you to consume adequate fruits during the monsoon season as this helps you restore energy.  But there is also choice of fruits as well.  Go for the items like pears, mangoes, apples and pomegranate. Even there are some fruits that helps bringing out pimples on your face. On order to remove pimples from your face, you need to avoid the fruits like muskmelon and water melon. Even consuming excessive mangoes can give rise to pimples.

2. Dry food

It is better not to go for the watery food during the monsoons such as juices available outside, lassi ad other watery fruits. Instead go for the dry category of food such as pea, flour, corn etc. As consumption of too much watery food during monsoon can give rise to swelling in your body. So, it’s better to avoid.

3. Increase your immunity

One of the major problems suffered by people during the monsoon season is reduction of immunity level in body. Today, there are ways in which you can easily increase your immunity level through home remedies. Whenever you are preparing soup, add a clove of garlic at the beginning ones the oil is hot. This will increase immunity level of an individual during monsoon.

4. Water

Since water borne diseases are quite common during the monsoon season, try not to drink water that is not purified. Even after filtration, it is better to drink the boiled water as this will kill all germs and bacteria that have formed in water.

5. Stay away from high blood pressure

If you have a problem of high blood pressure, it will be better to consume very little salt in meal or else this will give a boost to the problem of high blood pressure. Thus, it is important to avoid those food items that have good amount of salt.

6. Bitter vegetables

You should definitely have a dish of bitter vegetables in your meal such as neem, bitter gourd etc to avoid skin infections and allergies. If you don’t like to consume it in a boiled form, make a fried form to add taste in your tongue. This is a wonderful remedy to stay away from all types of skin infections.

7. Stay away from stagnation

During the monsoons, stagnant water will be very well available at your home and outside. It is really important to avoid stagnant water as this will give rise to diseases like malaria and dengue. You should always throw away the water inside the unused tank, flower pots as well as water coolers.  Since stagnant water is a place where the mosquito can breed, avoiding such stagnant water will be an important consideration when you are living in monsoons. Also don’t forget to place mosquito net or a repellent when you are asleep at night.

8. Medium low salt food

During monsoons when you are preparing meal for your family, it will be important for you to include low salt. During the monsoons people can get high blood pressure level due to salty food. Water retention is again another problem which can be checked with the help of low salt food.

9. Prefer dry fruit

Not all foods are good for all seasons. For example the watery fruits and juices are good during summer as we get dehydrated. But, during monsoons this can be a reason for trouble. The food such as watermelon, lassi, rice etc can create swelling in your body during monsoons. It is better consuming the food that is dry in nature.

10. Other forms of milk

During monsoons it is better to avoid milk. Rather, it will be good to consume other forms of milk in condense form such as yogurt, curd, sweet etc. If you want to drink milk, it is better to boil it in 100 degree Celsius and then drink it. This will help you stay away from the harmful germs that are likely to attack your body.

11. Avoid spicy food

During monsoon since the weather is not too hot or too cold, you will be inclined towards the spicy foods. But this will be absolutely a wrong step for you. You must avoid having spicy food during the monsoon season. It can lead to skin allergies and irritation.

1 person found this helpful

Pain killers and Heart Attack Risks!

FRHS, Ph.D Paed Neuro Rehabilitation, MPT - Neurology Physiotherapy, D.Sp.Med, DPHM (Health Management ), BPTh/BPT
Physiotherapist, Chennai
Pain killers and Heart Attack Risks!

 

  •  Doctors have found the use of pain relievers to treat respiratory infections like cold flu may increase the risk of heart attack.
  • For the study, researchers analyzed insurance claims from taiwan's national health insurance program from 2005 to 2011 with data from roughly 10, 000 patients who were hospitalized for a heart attack.
  • The purpose of the study was to assess whether cardiac risk factors from an acute respiratory infection and the use of non-steroidal anti-inflammatory, pain relievers combine to further increase the risk of heart attack.
1 person found this helpful

Eye Health - Exercises To Improve It!

MBBS Bachelor of Medicine and Bachelor of Surgery, MS - Ophthalmology, DNB Ophtalmology
Ophthalmologist, Navi Mumbai
Eye Health - Exercises To Improve It!

There are many common measures people take to improve their eyesight or to improve their vision, including wearing glasses, lenses, and many more. Here are some effective exercises, which can prove to be highly beneficial to improve your eye health:

1. Stretching
This is the most common and also one of the easiest to do. It requires you to just look up, hold for two seconds, look down, hold for two seconds and then repeat this procedure for each corner of your eye, which means top-left, top-right, bottom-left and bottom-right corners.

2. Flexing
This is simply rotating your eyes in circles. Roll your eyes in the clockwise direction for one minute and then roll your eyes in the anticlockwise direction for one minute.

3. Focus switching
This particular eye exercise is probably the most useful one to improve eye health. In this eye exercise, you have to hold something at a reading distance and cover the other eye. You then have to find something that is at least twenty feet away and trace its shape with one eye closed. With one eye closed, trace more shapes, which are twenty feet away.

4. Palming
This exercise is also very simple to perform. All you have to do is cover your eyes with your palms. Once you have done this, just wait and see that there are no bright flashes of light. If you see that there is a bright flash of light, just wait till they go. This is used primarily to distress the eyes.

5. Deep blinking
This is also an incredibly useful exercise for distance vision. What you have to do is to place some large letters are at a fair distance and then sit on a chair. You have to then close your eyes and tighten all your muscles for 5 seconds. After 5 seconds are over, you have to open your eyes and then you have to see the letters for a second or two. The more number of times you do this, the more clearly you will be able to see the letters after reopening your eyes. If you wish to discuss about any specific problem, you can consult an Ophthalmologist.

2718 people found this helpful

Radiofrequency (RF): Skin Tightening & Skin Rejuvenation!

BHMS, PG Diploma In Clinical Cosmetology (PGDCC)
Cosmetic Physician, Mumbai
Radiofrequency (RF): Skin Tightening & Skin Rejuvenation!

As the aging population in our society continues to grow, new technologies and procedures promising a more youthful appearance are continuously sought. The utilization of radiofrequency technology remains a novel method for the treatment of many aesthetic and medical dermatological indications. Innovative applications are constantly identified, expanding treatment options for various patient concerns including aging of the hands, cellulite, non-invasive lipolysis, and postpartum skin laxity. Non-invasive treatments are ideal for busy patients seeking minimal recovery time and so called lunch-time procedures. Furthermore, new developments in treatment devices enhance efficacy while decreasing patient discomfort. 

What is RF treatment? 

Based on the scientific term Radiofrequency (RF), radiofrequency treatment is a non-surgical means of “reshaping” the body and the face from beneath the superficial layer of the skin. This method uses sophisticated devices specifically designed to treat men and women’s most common skin aging problems like wrinkles, excess fatty tissues, or cellulite. The method utilizes radiofrequency waves which is, basically, heat energy meant for tissue remodelling and production of elastin and new collagen. Unlike invasive procedures which primarily affect the most superficial layers of the skin, the resulting heat of the Radiofrequency treatment works mainly on the deepest layer of the skin, the dermis, without affecting the upper layers that are above it such as the epidermis.

As heat is a stimulation that promotes contraction of the underlying tissues, especially at the dermis level, soft tissues found within that area of the body compress, realign, and even produce new collagen, a process that normally takes many months to complete. With healthy new collagen present from the deepest level of the skin, exposing such soft tissues to further Radiofrequency waves help sculpt and tighten those tissues into a more youthful and elastic surface. 

Benefits of RF treatment 

By now, you may already have an idea on how an RF treatment works with regards to aging problems common to both men and women. But how exactly does anyone experiencing treatment via RF benefits from it? Following are the benefits of RF treatment. 

  1. Diminishes or Removes Cellulite 
  2. Reduction of Body Fats 
  3. Tightening of the Skin/Anti-aging 
  4. Post-operative Liposuction Smoothing 
  5. Contour Reshaping 

Risks of RF treatment 

While the discovery of the Radiofrequency treatment is one of the best things to happen for the skincare industry, it is not perfect. In fact, the treatment itself has its own risks which may be experienced by some clients who undergo this type of medical procedure. 

Common side effects of RF treatment include: 

  1. Redness on the skin 
  2. Mild swelling 
  3. Oversensitivity of treated area 
  4. Sinking in of treated area 
  5. Blistering/bruising 

Who can NOT avail RF for skin tightening? 

Basically, anyone can avail of this form of treatment with a few exceptions such as pregnant or breast-feeding mothers and those with serious heart diseases or patients with pacemakers. 

Why should you Choose RF skin rejuvenation

If you are looking for a safe, painless and a non-surgical form of treatment for skin tightening, then Radiofrequency is the way to go. The procedure does not involve surgery, repositioning or cutting. In Radiofrequency treatment, the skin tightens due to the introduction of radio frequency energy into the skin. The process generates moderate electrical currents that cause a contraction of the collagen and reshape it, which results in the tightening of the skin. This treatment effectively tightens the dermis as well as the epidermis, while ensuring that your skin remains undamaged. Experience the benefits of RF skin rejuvenation at Clinic Cosmoderma. If you wish to discuss about any specific problem, you can consult a Cosmetic Physician.

2607 people found this helpful