Anti – NMDA Receptor Encephalitis, also known as NMDA Receptor Antibody Encephalitis is a condition in which the brain undergoes a state of acute inflammation, which can transform into something lethal if not given the proper treatment. Accurate treatment and precautionary measures can help the patient recover from the situation. The attacks comes from the immune system and the N – methyl D – aspartate receptor, NMDA is the target. Specifically, the immune system attacks the NR1 subunit of NMDA. A minimum number of cases get incorporated with tumours, teratomas of the ovaries, to be precise. Preliminary symptoms include headache, an upper respiratory infection and an illness synonymous to flu. Prodromal symptoms vary at different rates executing a number of neurological symptoms.
The test is a planned and precise one and helps diagnose a number of things. It diagnoses Viral Encephalitis like Rabies Virus, HSV, VZV, HIV, Arbovirus, HHV6/HHV7 and Cytomegalovirus. Indicates Autoimmune Encephalitis. Shows the presence of toxic and metabolic disorders.
CBC: Non – specific testing: →Presence of Leukocytosis indicating bacterial etiology. →Viral etiology due to relative lymphocytosis.
Testing of the serum: →Testing of HIV →Detection of rapid plasma reagin (RPR) for detecting syphilis. →Ruling out metabolic encephalopathy through liver function theories and electrolyte panelling. →Testing of convalescent and acute specimens using specific clinical methods. Serology for encephalitis in this case. →Tests for detection of geographical viruses.
Cerebrospinal Fluid (CSF) test: →Collect CSF about 20 cc. →The process as essential to eliminate meningitis. →Pressure is observed right at the beginning. →Cell count is measured. →Protein levels are observed. In this condition, the levels are often at the top of the bars. →Gram staining.
Type | Gender | Age-Group | Value |
---|---|---|---|
Anti NMDA IgG
|
UNISEX
|
All age groups
|
negative
|