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Nephrotic Syndrome - 9 Causes Of It That Will Surprise You!

DNB (Nephrology), MD, MBBS
Nephrologist, Delhi
Nephrotic Syndrome - 9 Causes Of It That Will Surprise You!
Nephrotic syndrome is a type of kidney disorder wherein, the body passes out excess amount of proteins through urine, owing to the damage caused to the tiny clusters of blood vessels in the kidneys. The symptoms include putting on excessive weight as a result of fluid retention, foamy urine and severe swelling around the region of the feet, ankles and eyes.

Common causes behind it:

Minimal change disease (also known as nil disease) leads to the abnormal functioning of the kidneys
Excess deposit of amyloid proteins in the organs, thus taking a toll on the filter mechanism of the kidneys.
Diabetes affecting the glomeruli (capillaries present in the nephrons of the kidneys).
Systemic lupus erythematous causing chronic swelling of your kidney.
Membranous nephropathy wherein the membranes in your glomeruli thicken.
Infections such as malaria, hepatitis C, hepatitis B and HIV.
Medications to combat infections and nonsteroidal anti-inflammatory drugs.
Treatment Available:

Kidney Biopsy is an essential part of disease assessment.
Angiotensin-converting enzyme inhibitors bring down blood pressure levels as well as the amount of protein discharged from the urine.
Water pills help control sweating, thus, increasing the fluid flushed from the kidneys.
Statins reduce cholesterol levels.
Blood thinners such as anticoagulants lower the risk of blood clots.
Corticosteroids regulate the immune system and ease the inflammation that results from kidney disorders.
Incorporating certain lifestyle changes such as opting for lean proteins, cutting on the intake of fat in the diet and consuming lesser amounts of salt can treat inflammation and swelling.
943 people found this helpful

Nephrotic Syndrome - Can Homeopathy Resolve It?

MD-Homeopathy, BHMS, Certified in Lifestyle Medicine
Homeopathy Doctor, Kolkata
Nephrotic Syndrome - Can Homeopathy Resolve It?
Nephrotic is a kidney dysfunction in which a person releases a huge amount of protein while urinating. This happens because of damaged blood vessels in the kidney which cannot properly filter water.

There are many treatments available for Nephrotic Syndrome. However, over the years, Homeopathy has shown greater results in the treatment of Nephrotic Syndrome. Homeopathy treats without affecting the kidneys and other organs. It cures Nephrotic Syndrome by reducing the symptoms of the disease.

Causes of Nephrotic Syndrome:

A cluster of tiny blood vessels in the kidney is called glomeruli. When the glomeruli are damaged, it can cause Nephrotic Syndrome.

Glomeruli helps in filtering the blood that passes through the kidney and separates the things body needs. Proper functioning of glomeruli vessel is to store the blood protein. This helps to maintain the correct measure of fluid in the body without letting it pass through the urine. Whereas a dysfunctional glomeruli vessel lets pass excessive blood protein through urine. This dysfunction of glomeruli causes Nephrotic Syndrome.

Health Risk Due to Nephrotic Syndrome:

There is a major health risk for a person who has Nephrotic Syndrome. Some of the health risks include:

Kidney Damage: With a damaged glomerulus, the risk of kidney damage increases by manifolds. Kidney becomes prone to diseases like lupus, diabetes, and other chronic diseases.

Insufficient Protein: Due to the excess flow of protein through the urine, it gets hard for the body to maintain a sufficient amount of protein in the body. Lack of protein can lead to weight loss, reduction of blood cells, and deficiency of vitamins.

Blood clots: Loss of blood protein increases the risk of forming blood clots inside the body. These blood clots are also known as thrombus.

Infection: A person suffering from Nephrotic Syndrome is highly prone to developing an infection.

High Blood Pressure: Due to an improper filter of glomeruli, a lot of waste keeps running in the bloodstream. This waste can be a major reason which can cause high blood pressure.

Homeopathic Treatment for Nephrotic Syndrome:

Homeopathic treatment is very effective for people with Nephrotic Syndrome. The first aim of this treatment is to reduce the disease. It controls the excess leakage of protein through homeopathic medicines. It increases immunity as patients with this syndrome are prone to infection. So, by increasing the immunity, chances of getting cold, throat infection, etc. are reduced.

Duration of treatment varies from patient to patient. It depends upon the severity of the disease. It also depends upon factors such as:

Immune system

Other medical conditions

General overall health

Duration of Nephrotic Syndrome

Cause of Nephrotic Syndrome

Homeopathic treatment medicines are based on the guidelines which concentrate on improving the immunity of a person. It tries to reduce the dependency on steroids, which are harmful in the long run. These homeopathic medicines aim to repair the damaged glomeruli vessels. These methods are clinically proven.

Conclusion:

Homeopathy does work in this type of disease. However, it is always advisable to consult a Homeopathy specialist before opting for any Homeopathy medicines and remedies.
1803 people found this helpful

Nephrotic Syndrome - How To Detect It?

MBBS, MD - Paediatrics, Fellowship in Neonatology
Pediatrician, Zirakpur
Nephrotic Syndrome - How To Detect It?
The nephrotic syndrome refers to kidney disease. Nephrotic syndrome is triggered when the glomeruli (tiny structures in the kidneys) malfunction or are damaged and allow too much protein to enter into the kidneys. Nephrotic syndrome is a chronic ailment but not very prevalent. In India, fewer than 1 million cases are reported every year.

Who is susceptible to Nephrotic Syndrome?
Children, especially between the ages 2-6 are vulnerable to coming down with this ailment. It is prevalent more amongst male children than female. Around 3-4 children out of 100,000 are affected by it. Age of onset determines how severe the syndrome will be.

What are the symptoms of Nephrotic Syndrome?
Nephrotic syndrome is characterized by swelling up of the face. The swelling spreads to other parts of the body. This is when most doctors will recommend a urine test to confirm if the child has contracted nephrotic syndrome.

Diagnosis of the disease-
Nephrotic syndrome can be diagnosed following procedures to test the presence of high cholesterol and low albumin levels in the blood. The doctor will also document the ratio of urinary protein to creatinine of more than 2 to confirm the diagnosis.

Nephrotic syndrome treatment-
The treatment options for the symptoms of nephrotic syndrome are as follows-

If nephrotic syndrome is detected in children less than 3 months of age, they will only require albumin transfusion and diuretic medication. For older children, oral steroids are trusted medication only after determining that there are no underlying diseases.
Parental counselling is necessary so that they can understand the medicine dosage, duration and side effects of steroidal treatment. Parents need to purchase uristix that can reveal protein levels in urine. It is imperative that parents regularly monitor their child s urine. This way, the syndrome does not become aggravated and the child does not need to be hospitalized.

Medication for nephrotic syndrome can be steroid sensitive or steroid insensitive.
In the case of steroid-sensitive medicines, swelling keeps recurring frequently or infrequently. But it is not followed by an infection. These are called relapses that require other immunosuppressive drugs. Regular follow up is recommended.
For steroid resistant medication, a kidney biopsy is mandated to understand the underlying cause of nephrotic syndrome. Based on the test results, the doctor initiates calcineurin inhibitor therapy. This procedure is performed by a pediatric nephrologist in children.

The dosage depends on the child s weight. Inadequate or overdose can harm the child.

The side effects of steroids include-

Cushingoid facies (fat deposits on the face)
Hypertension
Obesity
Short stature

When a child takes immunosuppressive drugs, she/he becomes exposed to infections and might require vaccinations (Oral OPV i.e. pulse polio program, BCG, measles, MMR vaccine).

Diet for nephrotic syndrome-
A proper diet can work wonders in controlling the symptoms of nephrotic syndrome. A doctor usually recommends cutting down on salt and advises minimum intake of fluids. Since cholesterol levels go up with this syndrome, a diet low in saturated fats is suggested. Even though nephrotic syndrome is accompanied by loss of proteins, a high protein diet is not recommended because proteins aggravate the syndrome.

When the underlying causes of nephrotic syndrome (other diseases that trigger it) are cured, the symptoms of nephrotic disorder dissipate. The proper diet and medication will ensure that a child outgrows the disease and lives a healthy life.
1822 people found this helpful

Congenital Nephrotic Syndrome - Know Signs Of It In Children!

MD Physician, DNB (Nephrology), DNB (General Medicine)
Nephrologist, Delhi
Congenital Nephrotic Syndrome - Know Signs Of It In Children!
As the name suggests, congenital nephrotic syndrome affects the kidneys of newborn babies. Though congenital means the disease must be present from birth, babies who develop nephrotic syndrome in the first three months are also said to suffer from this condition. This is a rare genetic disorder that is passed down from parents to their children. Boys are at a higher risk of suffering from this disorder than girls. The congenital nephrotic syndrome causes the kidneys to leak large amounts of protein into the baby s urine. This can lead to swelling of the body tissues and a weakened immune system.

Some of the common symptoms of this disease include

Low birth weight
Lack of appetite
Swelling of the body
Foamy or frothy urine
Lowered urine production
Cough
Pregnant women are usually screened for this condition before the baby is born. The doctor will be looking for a placenta that is larger than normal in ultrasound and high levels of alpha fetoprotein in amniotic fluid samples. If found; the doctor might ask for a genetic test to confirm the diagnosis.

Once the baby is born, he or she will show signs of fluid retention as the body begins to swell. Other signs your doctor will look out for are high blood pressure, signs of malnutrition and abnormal sounds from the heart and lungs. A urine analysis will also show high levels of protein in the urine through the overall protein levels in the body may be low. The doctor may also ask for a kidney biopsy in some cases to confirm the diagnosis.

Aggressive forms of treatment in the early stages of this disease can help control it. This may include antibiotics, blood pressure medication, ACE inhibitors and angiotensin receptor blockers to reduce protein leakage and diuretics to manage excess fluid build-up. Nonsteroidal anti-inflammatory drugs may also help reduce the amount of protein leaking into the urine. In addition, the doctor may advise you to limit fluid the baby s fluid intake to control the swelling. As a last resort, the kidneys may need to be removed to prevent protein loss. This will be followed by dialysis or a kidney transplant.

If left unchecked, this disorder can lead to a number of complications including acute kidney failure, blood clots, infections and diseases related to malnutrition. It can also lead to the death of a baby in the first year of catching the infection or before his or her fifth birthday.
1308 people found this helpful

Nephrotic Syndrome - How To Get Rid Of It?

DNB (Nephrology), MRCP (UK), MD - Medicine, MBBS
Nephrologist, Mumbai
Nephrotic Syndrome - How To Get Rid Of It?
Nephrotic syndrome is a type of kidney disorder wherein, the body passes out excess amount of proteins through urine, owing to the damage caused to the tiny clusters of blood vessels in the kidneys. The symptoms include putting on excessive weight as a result of fluid retention, foamy urine and severe swelling around the region of the feet, ankles and eyes.

Common causes behind it

Minimal change disease (also known as nil disease) leads to the abnormal functioning of the kidneys
Excess deposit of amyloid proteins in the organs, thus taking a toll on the filter mechanism of the kidneys.
Diabetes affecting the glomeruli (capillaries present in the nephrons of the kidneys).
Systemic lupus erythematous causing chronic swelling of your kidney.
Membranous nephropathy wherein the membranes in your glomeruli thicken.
Infections such as malaria, hepatitis C, hepatitis B and HIV.
Medications to combat infections and nonsteroidal anti-inflammatory drugs.
Treatment Available

Kidney Biopsy is an essential part of disease assessment.
Angiotensin-converting enzyme inhibitors bring down blood pressure levels as well as the amount of protein discharged from the urine.
Water pills help control sweating, thus, increasing the fluid flushed from the kidneys.
Statins reduce cholesterol level.
Blood thinners such as anticoagulants lower the risk of blood clots.
Corticosteroids regulate the immune system and ease the inflammation that results from kidney disorders.
Incorporating certain lifestyle changes such as opting for lean proteins, cutting on the intake of fat in the diet and consuming lesser amounts of salt can treat inflammation and swelling.
3643 people found this helpful

Nephrotic Syndrome - Know Options Of Treatment!

MBBS,MD(medicine), MD- Medicine, DNB- Nephrology
Nephrologist, Ahmedabad
Nephrotic Syndrome - Know Options Of Treatment!
Nephrotic syndrome is a type of kidney disorder wherein, the body passes out excess amount of proteins through urine, owing to the damage caused to the tiny clusters of blood vessels in the kidneys. The symptoms include putting on excessive weight as a result of fluid retention, foamy urine and severe swelling around the region of the feet, ankles and eyes.

Common causes behind it

Minimal change disease (also known as nil disease) leads to the abnormal functioning of the kidneys
Excess deposit of amyloid proteins in the organs, thus taking a toll on the filter mechanism of the kidneys.
Diabetes affecting the glomeruli (capillaries present in the nephrons of the kidneys).
Systemic lupus erythematous causing chronic swelling of your kidney.
Membranous nephropathy wherein the membranes in your glomeruli thicken.
Infections such as malaria, hepatitis C, hepatitis B and HIV.
Medications to combat infections and nonsteroidal anti-inflammatory drugs.
Treatment Available

Kidney Biopsy is an essential part of disease assessment.
Angiotensin-converting enzyme inhibitors bring down blood pressure levels as well as the amount of protein discharged from the urine.
Water pills help control sweating, thus, increasing the fluid flushed from the kidneys.
Statins reduce cholesterol level.
Blood thinners such as anticoagulants lower the risk of blood clots.
Corticosteroids regulate the immune system and ease the inflammation that results from kidney disorders.
Incorporating certain lifestyle changes such as opting for lean proteins, cutting on the intake of fat in the diet and consuming lesser amounts of salt can treat inflammation and swelling.
3871 people found this helpful

Nephrotic Syndrome - Can Diet Help In It?

DNB (Nephrology), M.D ( Internal Medicine), MBBS
Nephrologist, Noida
Nephrotic Syndrome - Can Diet Help In It?
Nephrotic Syndrome is a condition which is characterised by the loss of protein into the urine (called proteinuria) as a result of increased glomerular permeability and oedema. This results in low protein level in the blood. The low levels of protein in blood result in the drawing of fluids into soft tissues. A severe form hypoalbuminemia can cause scores of secondary diseases such as ascites (retention of fluid in the abdominal cavity), pleural effusion (build-up of fluids between the lungs and the chest), or high cholesterol. It can also result in retention of fluid in other parts of the body such as eyelids, lower extremities etc.

What can cause this?
Nephrotic syndrome is mainly caused by damage to the kidneys. This leads to an increase in the concentration of protein in the urine. In adults, it can be caused due to glomerulonephritis or damage to the glomerulus of the kidneys while in children it is likely caused by minimal change disease (kidney disease marked by the abnormal loss of protein through the urine).

The other common causes of nephritic syndromes are:

Genetic disorder
Immune disorder
Cancer
Infection
Use of specific drugs
Certain diseases such as diabetes mellitus, lupus
The incidence of this disease is seen more often in males than in females.
Diet that is recommended in Nephrotic Syndrome:
In patients diagnosed with Nephrotic syndrome, the intake of salt, fat and protein must be checked. There should be emphasis on the consumption of dietary fibres that are present in vegetables and fruits.
The intake of protein and fluid should also be monitored, but this solely depends on personal factors such as age, weight and condition of the patient. It is recommended to consult a renal dietician who can guide you appropriately.

Sodium/salt intake: The sodium or salt intake must be restricted as it leads to high blood pressure and results in fluid retention in the body, thus causing oedema (build-up of fluids within the body cavities and tissues) in the body. Avoid processed food as it contains a lot of salt.
Protein intake: Protein is an essential part of the diet as it helps in the general makeup of the body and development of muscles. The consumption of protein must be kept under check and it is the best to consult your dietician for this. Loss of protein in urine needs to be replaced by class 1 high quality proteins in nephrotic syndrome.
Limit fat and cholesterol intake: It is always good to curb on bad cholesterol as it is the reason behind several heart diseases. But, with patients diagnosed with Nephrotic Syndrome, it is highly recommended to avoid food rich in fats. This means staying away from unhealthy fatty meat or junk food.
Fluid intake: Fluid intake does not have to be necessarily reduced, but it is always good to consult your doctor for the same.
You are what you eat . Nephrotic syndrome can slowly progress to chronic kidney disease if the necessary steps are not taken to curb it in an early stage, and diet control is a major way to do so.
3126 people found this helpful

Nephrotic Syndrome - How To Handle It?

MBBS Bachelor of Medicine and Bachelor of Surgery, DNB - MEdicine, DNB- Nephrology
Nephrologist, Gurgaon
Nephrotic Syndrome - How To Handle It?
Nephrotic syndrome is a type of kidney disorder wherein, the body passes out the excess amount of proteins through urine, owing to the damage caused to the tiny clusters of blood vessels in the kidneys. The symptoms include putting on excessive weight as a result of fluid retention, foamy urine and severe swelling around the region of the feet, ankles and eyes.

Common causes behind it:

Minimal change disease (also known as nil disease) leads to the abnormal functioning of the kidneys
Excess deposit of amyloid proteins in the organs, thus taking a toll on the filter mechanism of the kidneys.
Diabetes affecting the glomeruli (capillaries present in the nephrons of the kidneys).
Systemic lupus erythematous causing chronic swelling of your kidney.
Membranous nephropathy wherein the membranes in your glomeruli thicken.
Infections such as malaria, hepatitis C, hepatitis B and HIV.
Medications to combat infections and nonsteroidal anti-inflammatory drugs.
Treatment Available

Kidney Biopsy is an essential part of disease assessment.
Angiotensin-converting enzyme inhibitors bring down blood pressure levels as well as the amount of protein discharged from the urine.
Statins reduce cholesterol level.
Blood thinners such as anticoagulants lower the risk of blood clots.
Corticosteroids regulate the immune system and ease the inflammation that results from kidney disorders.
Incorporating certain lifestyle changes such as opting for lean proteins, cutting on the intake of fat in the diet and consuming lesser amounts of salt can treat inflammation and swelling.
1995 people found this helpful

Nephrotic Syndrome - How To Treat It?

MBBS Bachelor of Medicine and Bachelor of Surgery, DNB - General Medicine, DNB - Nephrology
Nephrologist, Pune
Nephrotic Syndrome - How To Treat It?
Nephrotic syndrome is a type of kidney disorder wherein, the body passes out excess amount of proteins through urine, owing to the damage caused to the tiny clusters of blood vessels in the kidneys. The symptoms include putting on excessive weight as a result of fluid retention, foamy urine and severe swelling around the region of the feet, ankles and eyes.

Common causes behind it

Minimal change disease (also known as nil disease) leads to the abnormal functioning of the kidneys
Excess deposit of amyloid proteins in the organs, thus taking a toll on the filter mechanism of the kidneys.
Diabetes affecting the glomeruli (capillaries present in the nephrons of the kidneys).
Systemic lupus erythematous causing chronic swelling of your kidney.
Membranous nephropathy wherein the membranes in your glomeruli thicken.
Infections such as malaria, hepatitis C, hepatitis B and HIV.
Medications to combat infections and nonsteroidal anti-inflammatory drugs.
Treatment Available

Kidney Biopsy is an essential part of disease assessment.
Angiotensin-converting enzyme inhibitors bring down blood pressure levels as well as the amount of protein discharged from the urine.
Statins reduce cholesterol level.
Blood thinners such as anticoagulants lower the risk of blood clots.
Corticosteroids regulate the immune system and ease the inflammation that results from kidney disorders.
Incorporating certain lifestyle changes such as opting for lean proteins, cutting on the intake of fat in the diet and consuming lesser amounts of salt can treat inflammation and swelling.
2570 people found this helpful

Nephrotic Syndrome

MBBS, MD - General Medicine, DM - Nephrology, DNB (Nephrology)
Nephrologist, Delhi
Play video
Hi,

I am Dr. Yogesh Kumar Chhabra, Nephrologist. Aaj me baat krunga nephrotic syndrome ke bare me. Is problem me urine ki quantity badh jati hai, swelling ho jati hai, hypertension ho jata hai. Ye problem mainly bachon me dekhi jati hai. Jo bache medications ke through steroids pe response nhi krte hain to hum biopsy ke bare me sochte hain. Kuch bachon me biopsy ke bina bhi treatment ho jata hai. Isme hum kidney ko diagnose krte hain. Ye ek minor procedure hai. Ye treatment hum ultrasound and medications ke through dete hain.

Kayi cases me ye problem diabetes, blood pressure, hepatitis B & C ki vjha se bhi ho jati hai. Treatment patient to patient vary krta hai. 90% cases me result acha dekha jata hai. Or agar kuch patients me acha effect nhi hai treatment ka to hum 2nd line of the treatment dekhte hain. Kuch cases me hota hai ki protein ki leakage nhi ruk pati hai. Agar timely treatment na dia jaye to chronic kidney disease ka problem ho jata hai. Aisa case bhi ban jata hai ki patient ko dialysis ki jrurat pad jati hai.

Nephrotic synrome me RBC ka leakage hota hai. Patient ko skin infection ho skta hai. Young adults me nephropathy ka problem ho jata hai. Patient ko vasculitis ka problem bhi ho skta hai. Kayi cases me rheumotoid arthritis ka problem bhi ho jata hai. Kafi hadd tak nephrology me correction kia ja skta hai. Islia timely treatment important hai. Islia aap apne Dr se apni problem discuss kren.

Thank You.
3915 people found this helpful