Bone Marrow - NSE Stain Test

Bone marrow is the spongy tissue inside some of the bones in the body, including the hip and thigh bones. When an individual faces an acute leukaemia composed entirely of blasts, one way to figure out the identity of those blasts is to use cytochemical stains. One of the most commonly used cytochemical stains is the NSE stain or the non-specific esterase stain. Bone Marrow NSE Stain test is performed on a sample of bone marrow to measure the level of Bone Marrow Pathology in the bone marrow and also to detect conditions arising from irregular results of this test such as Leukaemia and Lymphoma.

While getting ready for bone marrow NSE stain, no special preparation is required for the same . The doctors must ensure that the patient is not undergoing some other medication. Thereafter with the doctors advice the necessary procedures will be carried out and samples will be obtained based on which accurate information will be gathered for effective diagnosis and appropriate treatment.

The normal result for Bone Marrow NSE Stain Microscopy Bone Marrow for Bone Marrow Pathology is Monocytes and their precursors stain red for Unisex gender and for All age groups. If a patient has leukaemia composed of a sea of undifferentiated blasts, the blood or marrow smears or the bone marrow section should be stained with NSE. If the cells stain red, then the patient is probably dealing with a leukaemia composed of monocytic cells – probably a monoblastic leukaemia, if all that is seen in the samples is blasts then,It’s a quick and easy way to help you diagnose the leukaemia.

The bone marrow samples are collected either through a bone marrow biopsy or a bone marrow aspiration A bone marrow biopsy removes a small amount of bone and a small amount of fluid and cells from inside the bone whereas a bone marrow aspiration removes only the marrow. Once the samples are collected a Bone Marrow NSE Stain Microscopy Bone Marrow is done using Microscopy method on a Bone Marrow sample, These stains are applied to slides – either smears (blood or bone marrow) or sections (of bone marrow) and are read under the microscope.