Brucella IgG Antibody Tips

Immunity –bal (बल) and ayurveda

In different stages of the life it is important that we maintain a healthy one, the specific system has been developed in form of सहजबल, कालबल, और युक्तिकृतबल with the help of which you get strength (बल-bal) throughout the life. System of this procedure of medicines is known as संस्कार.

What is sanskar (संस्कार)?

“संस्कारो हि गुणान्तराधानं”
संस्कार is the procedure of adulteration of quality of life or enhancing the good things.

Suvarnaprashan - a powerful child immunization procedure

सुवर्णप्राशनं ह्येतनमेधाग्निबलवर्धनम् | आयुष्यम मङ्गलं पुण्यं वृष्यम वर्णयं ग्रहापहम ||
म|सात परममेधावी व्याधिर्भिन च धृष्यते | षड़भिर्मासै: श्रुतधर: सुवर्णप्राशनाद्भवेत || का.सं.सू.

If you are looking for an effective ayurvedic way, which helps in boosting your child’s immunity and health, you should opt for सुवर्णप्राशन. Suvarnaprashan, used over thousands of years, is completely natural as it is prepared from gold (सूवर्ण), medicated gow ghrita (औषधीय घृत) and honey (मधु), which goes through proper processing according to completely safe classic ayurvedic method. It’s a licking foam preparation (लेह/लिढ प्रकार औषधी). It is ideal method for building the overall health and intelligence of your child.

The specific benefits ascribed to svarnaprashan are as follows

Medha agni bala vardhanam (improvement of intellect, digestion, metabolism, immunity, and physical strength) ayushyam (promoting lifespan) mangalam (auspicious) punyam (righteous) vrushyam (aphrodisiac) varnyam (enhancement of color and complexion) grahapaham (protection from evil spirits and microorganisms)

How suvarnaprashan works?

The three components of suvarnaprashan work together towards enhancing the immunity and as each of them individually works on the betterment of immunity.

Goldit is an immuno-modulator (i. E. It reconstructs the immune system) provides bal to the bodyenhances life potencyenriches the texture of the skinpharmacological studies showed specific and nonspecific immune responses, which were modified in a positive manner in swarna bhasma treated. It also had a stimulatory effect on peritonealmacrophages, which may be helpful to fight against infections. Note: it is evidently mentioned in the texts of ayurveda that any form of gold should be used internally only after proper purification failing to do, which may result in complications that may be even life-threatening. The type of gold to be used, mode of administration of different forms, theirs benefits and therapeutic indications are also clearly explainedcow ghrit or gheeresearch indicates that phenolic antioxidants present in the ghee help in boosting the immune systemit is rich in vitamin a & e, which help fight free radicals and promote good healthcla (conjugated linolenic acid) in ghee lowers the level of bad cholesterol (low-density lipoprotein) and triglycerides in the body. Ghee also improves our vision by helping our bodies properly digest fat-soluble vitamins such as vitamin a. It detoxifies the body by dissolving the toxins, which are then excreted out of the body through intestine. Butyric acid, is the most important element in ghee, which has also been linked to the stimulation of t-cell production, which are the heavy hitting cells of the immune system. The use of cow ghee can help supercharge your immune system. Dose shaman of vata (वात) and pitta (पित्त) vikar (it balances the vata and pita dosha) rasa, shukra and oja vardhank (appharodiatic in nature and improve immunity) sanskarasya anuvartanam (gives a boost to the potency of the medication) twachya (enhances the complexion of the skin) dhee, dhruti, smruti, medha vardhak (enhances the intellectual power of the brain) agni vardhak (amplifies the digestive fire) honeyhoney contains a protein made by bees called defensin-1, which is the most active germ killing ingredient in honey. It makes the penetration of other medicines easy. Easily palatable for childrencontains high level of nutrients and glucosechakshusya (चक्षुष्य) (improves eyesight) vishahara (वृष्य) (aphrodisiac in nature) rakta, pittahara (रक्त & पित्तहर) (takes care of blood and pitta imbalance)

Research findings

In a pharmaco-clinical study conducted on neonates madhu-ghrita-swarna-vacha combination shows a significant effect on humoral antibody formation and it acted on immunological system, which was evident by triggering the response of immunological system by a rise in the total proteins and serum igg levels.

Observations noted

The problems like bed wetting and indigestion are decreasedreduced recurrency of frequent cough and cold. Reduced hospital visitshyperactive children become calm and it enhances concentrationchildrens are taking interest in study and sportssuvarnaprashan increases immunity power in disorders like epileptic convulsion, allergy, hepatitis-bimproves speech

Things to note

Suvarnaprashan can be given to your child from childbirth till the age of 12 years. Ideally, it should be given early in the morning on an empty stomach. Feed your child 30 minutes after giving suvarnaprashan. The specific benefits of swarnaprashana according to the duration of administration have been mentioned such as: if administered for 1 month, the baby will become parama medhavi (highly intelligent) and vyadhibhir na cha drusyate (will not be affected by any disease) if administered for 6 months, the baby will become srutadhara (will be able to remember the things, which are just heard. You can follow a dosage for a period of 30 days. You may extend this till 180 days. Afterwards follow up on every pushyanaxatra (पुष्यनक्षत्र. Your child should face the east side when taking this medicine. Suvarnaprashan is also known by other names such as swarna amruta prashana, swarna bindu prashana, suvarnaprashan, swarna prashana and swarnaprashan.

However, in conditions such as acute fever, swarnprashan can increase your body temperature. It is contraindicative in condition such as diarrhea, vomiting. Hence, it is important to consult an experienced and well-known ayurveda practitioner before starting this ayurveda process

 

Immunity –Bal(बल) and Ayurveda
In different stages of the life it is important that we maintain a healthy one, the specific system has been developed in form of सहजबल, कालबल, और युक्तिकृतबल with the help of which you get Strength (बल-Bal) throughout the life. System of this procedure of medicines is known as संस्कार.

What is Sanskar(संस्कार)?
“संस्कारो हि गुणान्तराधानं”
संस्कार is the procedure of Adulteration of quality of life  or enhancing the good things.

Shuvarnprashan - A powerful Child Immunization Procedure

सुवर्णप्राशनं ह्येतनमेधाग्निबलवर्धनम् | आयुष्यम मङ्गलं पुण्यं वृष्यम वर्णयं ग्रहापहम ||
मसात परममेधावी व्याधिर्भिन च धृष्यते | षड़भिर्मासै: श्रुतधर: सुवर्णप्राशनाद्भवेत || का.सं.सू.

If you are looking for an effective Ayurvedic way, which helps in boosting your child’s immunity and health, you should opt for सुवर्णप्राशन.  Shuvarnprashan, used over thousands of years, is completely natural as it is prepared from Gold (सूवर्ण), Medicated Gow Ghrita (औषधीय घृत) and Honey (मधु), which goes through proper processing according to completely safe classic Ayurvedic Method. It’s a licking foam preparation (लेह/लिढ प्रकार औषधी). It is ideal method for building the overall health and intelligence of your child.

The specific benefits ascribed to Shuvarnprashan are as follows

1. Medha Agni Bala Vardhanam (improvement of intellect, digestion, metabolism, immunity, and physical strength)
2. Ayushyam (promoting lifespan)
3. Mangalam (auspicious)
4. Punyam (righteous)
5. Vrushyam (aphrodisiac)
6. Varnyam (enhancement of color and complexion)
7. Grahapaham (protection from evil spirits and microorganisms)

How Shuvarnprashan works?

The three components of Shuvarnprashan work together towards enhancing the immunity and as each of them individually works on the betterment of immunity.

1. Gold
   1. It is an immuno-modulator (i.e. it reconstructs the immune system)
   2. Provides bal to the body
   3. Enhances life potency
   4. Enriches the texture of the skin
   5. Pharmacological studies showed specific and nonspecific immune responses, which were modified in a positive manner in Swarna Bhasma treated. It also had a stimulatory effect on peritoneal macrophages, which may be helpful to fight against infections.
   6. Note: It is evidently mentioned in the texts of Ayurveda that any form of gold should be used internally only after proper purification failing to do, which may result in complications that may be even life-threatening.The type of gold to be used, mode of administration of different forms, theirs benefits and therapeutic indications are also clearly explained
2. Cow Ghrit or Ghee
   1. Research indicates that phenolic antioxidants present in the ghee help in boosting the immune system
   2. It is rich in vitamin A & E, which help fight free radicals and promote good health
   3. CLA ( conjugated linolenic acid) in ghee lowers the level of bad cholesterol (low-density lipoprotein) and triglycerides in the body.
   4. Ghee also improves our vision by helping our bodies properly digest fat-soluble vitamins such as Vitamin A.
   5. It detoxifies the body by dissolving the toxins, which are then excreted out of the body through intestine. 
   6. Butyric acid, is the most important element in ghee, which has also been linked to the stimulation of T-cell production, which are the heavy hitting cells of the immune system. 
   7. The use of cow ghee can help supercharge your immune system.
   8. Dose shaman of Vata(वात) and Pitta(पित्त) Vikar (It balances the Vata and Pita dosha)
   9. Rasa, Shukra and Oja Vardhank ( Appharodiatic in nature and Improve Immunity)
   10. Sanskarasya Anuvartanam (Gives a boost to the potency of the medication)
   11. Twachya (Enhances the complexion of the skin)
   12. Dhee, Dhruti, Smruti, Medha vardhak ( Enhances the intellectual power of the brain)
   13. Agni Vardhak(Amplifies the digestive fire)
3. Honey
   1. Honey contains a protein made by bees called defensin-1, which is the most active germ killing ingredient in honey.
   2. It makes the penetration of other medicines easy.
   3. Easily palatable for children
   4. Contains high level of nutrients and glucose
   5. Chakshusya(चक्षुष्य) (Improves eyesight)
   6. Vishahara(वृष्य) (Aphrodisiac in nature)
   7. Rakta, Pittahara (रक्त & पित्तहर) ( Takes care of blood and pitta imbalance)

Research Findings

In a pharmaco-clinical study conducted on neonates Madhu-Ghrita-Swarna-Vacha Combination shows a significant effect on humoral antibody formation and it acted on immunological system, which was evident by triggering the response of immunological system by a rise in the total proteins and serum IgG levels.

Observations noted

1. The problems like bed wetting and indigestion are decreased
2. Reduced recurrency of frequent cough and cold. Reduced hospital visits
3. Hyperactive children become calm and it enhances concentration
4. Childrens are taking interest in study and sports
5. Shuvarnprashan increases immunity power in disorders like epileptic convulsion, allergy, Hepatitis-B
6. Improves speech

Things to note

1. Shuvarnprashan can be given to your child from childbirth till the age of 12 years.
2. Ideally, it should be given early in the morning on an empty stomach. Feed your child 30 minutes after giving Shuvarnprashan.
3. The specific benefits of Swarnaprashana according to the duration of administration have been mentioned such as:
   • If administered for 1 month, the baby will become Parama Medhavi (highly intelligent) and Vyadhibhir Na Cha Drusyate (will not be affected by any disease)
   • If administered for 6 months, the baby will become Srutadhara (will be able to remember the things, which are just heard).
   • You can follow a dosage for a period of 30 days. You may extend this till 180 days. Afterwards follow up on every pushyanaxatra(पुष्यनक्षत्र).
   • Your child should face the east side when taking this medicine. Shuvarnprashan is also known by other names such as Swarna amruta prashana, Swarna bindu prashana, Suvarna prashan, Swarna prashana and Swarnaprashan.

However, in conditions such as acute fever, swarnprashan can increase your body temperature. It is contraindicative in condition such as diarrhea, vomiting. Hence, it is important to consult an experienced and well-known Ayurveda practitioner before starting this Ayurveda process

Immunity –Bal(बल) and Ayurveda
In different stages of the life it is important that we maintain a healthy one, the specific system has been developed in form of सहजबल, कालबल, और युक्तिकृतबल with the help of which you get Strength (बल-Bal) throughout the life. System of this procedure of medicines is known as संस्कार.

What is Sanskar(संस्कार)?
“संस्कारो हि गुणान्तराधानं”
संस्कार is the procedure of Adulteration of quality of life  or enhancing the good things.

Suvarnaprashan - A powerful Child Immunization Procedure

सुवर्णप्राशनं ह्येतनमेधाग्निबलवर्धनम् | आयुष्यम मङ्गलं पुण्यं वृष्यम वर्णयं ग्रहापहम ||
म|सात परममेधावी व्याधिर्भिन च धृष्यते | षड़भिर्मासै: श्रुतधर: सुवर्णप्राशनाद्भवेत || का.सं.सू.

If you are looking for an effective Ayurvedic way, which helps in boosting your child’s immunity and health, you should opt for सुवर्णप्राशन.  Suvarnaprashan, used over thousands of years, is completely natural as it is prepared from Gold (सूवर्ण), Medicated Gow Ghrita (औषधीय घृत) and Honey (मधु), which goes through proper processing according to completely safe classic Ayurvedic Method. It’s a licking foam preparation (लेह/लिढ प्रकार औषधी). It is ideal method for building the overall health and intelligence of your child.

The specific benefits ascribed to Svarnaprashan are as follows

1. Medha Agni Bala Vardhanam (improvement of intellect, digestion, metabolism, immunity, and physical strength)
2. Ayushyam (promoting lifespan)
3. Mangalam (auspicious)
4. Punyam (righteous)
5. Vrushyam (aphrodisiac)
6. Varnyam (enhancement of color and complexion)
7. Grahapaham (protection from evil spirits and microorganisms)

How Suvarnaprashan works?

The three components of Suvarnaprashan work together towards enhancing the immunity and as each of them individually works on the betterment of immunity.

1. Gold
   1. It is an immuno-modulator (i.e. it reconstructs the immune system)
   2. Provides bal to the body
   3. Enhances life potency
   4. Enriches the texture of the skin
   5. Pharmacological studies showed specific and nonspecific immune responses, which were modified in a positive manner in Swarna Bhasma treated. It also had a stimulatory effect on peritoneal macrophages, which may be helpful to fight against infections.
   6. Note: It is evidently mentioned in the texts of Ayurveda that any form of gold should be used internally only after proper purification failing to do, which may result in complications that may be even life-threatening.The type of gold to be used, mode of administration of different forms, theirs benefits and therapeutic indications are also clearly explained
2. Cow Ghrit or Ghee
   1. Research indicates that phenolic antioxidants present in the ghee help in boosting the immune system
   2. It is rich in vitamin A & E, which help fight free radicals and promote good health
   3. CLA ( conjugated linolenic acid) in ghee lowers the level of bad cholesterol (low-density lipoprotein) and triglycerides in the body.
   4. Ghee also improves our vision by helping our bodies properly digest fat-soluble vitamins such as Vitamin A.
   5. It detoxifies the body by dissolving the toxins, which are then excreted out of the body through intestine. 
   6. Butyric acid, is the most important element in ghee, which has also been linked to the stimulation of T-cell production, which are the heavy hitting cells of the immune system. 
   7. The use of cow ghee can help supercharge your immune system.
   8. Dose shaman of Vata(वात) and Pitta(पित्त) Vikar (It balances the Vata and Pita dosha)
   9. Rasa, Shukra and Oja Vardhank ( Appharodiatic in nature and Improve Immunity)
   10. Sanskarasya Anuvartanam (Gives a boost to the potency of the medication)
   11. Twachya (Enhances the complexion of the skin)
   12. Dhee, Dhruti, Smruti, Medha vardhak ( Enhances the intellectual power of the brain)
   13. Agni Vardhak(Amplifies the digestive fire)
3. Honey
   1. Honey contains a protein made by bees called defensin-1, which is the most active germ killing ingredient in honey.
   2. It makes the penetration of other medicines easy.
   3. Easily palatable for children
   4. Contains high level of nutrients and glucose
   5. Chakshusya(चक्षुष्य) (Improves eyesight)
   6. Vishahara(वृष्य) (Aphrodisiac in nature)
   7. Rakta, Pittahara (रक्त & पित्तहर) ( Takes care of blood and pitta imbalance)

Research Findings

In a pharmaco-clinical study conducted on neonates Madhu-Ghrita-Swarna-Vacha Combination shows a significant effect on humoral antibody formation and it acted on immunological system, which was evident by triggering the response of immunological system by a rise in the total proteins and serum IgG levels.

Observations noted

1. The problems like bed wetting and indigestion are decreased
2. Reduced recurrency of frequent cough and cold. Reduced hospital visits
3. Hyperactive children become calm and it enhances concentration
4. Childrens are taking interest in study and sports
5. Suvarnaprashan increases immunity power in disorders like epileptic convulsion, allergy, Hepatitis-B
6. Improves speech

Things to note

1. Suvarnaprashan can be given to your child from childbirth till the age of 12 years.
2. Ideally, it should be given early in the morning on an empty stomach. Feed your child 30 minutes after giving Suvarnaprashan.
3. The specific benefits of Swarnaprashana according to the duration of administration have been mentioned such as:
   • If administered for 1 month, the baby will become Parama Medhavi (highly intelligent) and Vyadhibhir Na Cha Drusyate (will not be affected by any disease)
   • If administered for 6 months, the baby will become Srutadhara (will be able to remember the things, which are just heard).
   • You can follow a dosage for a period of 30 days. You may extend this till 180 days. Afterwards follow up on every pushyanaxatra(पुष्यनक्षत्र).
   • Your child should face the east side when taking this medicine. Suvarnaprashan is also known by other names such as Swarna amruta prashana, Swarna bindu prashana, Suvarnaprashan, Swarna prashana and Swarnaprashan.

However, in conditions such as acute fever, swarnprashan can increase your body temperature. It is contraindicative in condition such as diarrhea, vomiting. Hence, it is important to consult an experienced and well-known Ayurveda practitioner before starting this Ayurveda process

Immunity –Bal(बल) and Ayurveda
In different stages of the life it is important that we maintain a healthy one, the specific system has been developed in form of सहजबल, कालबल, और युक्तिकृतबल with the help of which you get Strength (बल-Bal) throughout the life. System of this procedure of medicines is known as संस्कार.

What is Sanskar(संस्कार)?
“संस्कारो हि गुणान्तराधानं”
संस्कार is the procedure of Adulteration of quality of life  or enhancing the good things.

Shuvarnprashan - A powerful Child Immunization Procedure

सुवर्णप्राशनं ह्येतनमेधाग्निबलवर्धनम् | आयुष्यम मङ्गलं पुण्यं वृष्यम वर्णयं ग्रहापहम ||
मसात परममेधावी व्याधिर्भिन च धृष्यते | षड़भिर्मासै: श्रुतधर: सुवर्णप्राशनाद्भवेत || का.सं.सू.

If you are looking for an effective Ayurvedic way, which helps in boosting your child’s immunity and health, you should opt for सुवर्णप्राशन.  Shuvarnprashan, used over thousands of years, is completely natural as it is prepared from Gold (सूवर्ण), Medicated Gow Ghrita (औषधीय घृत) and Honey (मधु), which goes through proper processing according to completely safe classic Ayurvedic Method. It’s a licking foam preparation (लेह/लिढ प्रकार औषधी). It is ideal method for building the overall health and intelligence of your child.

The specific benefits ascribed to Shuvarnprashan are as follows

1. Medha Agni Bala Vardhanam (improvement of intellect, digestion, metabolism, immunity, and physical strength)
2. Ayushyam (promoting lifespan)
3. Mangalam (auspicious)
4. Punyam (righteous)
5. Vrushyam (aphrodisiac)
6. Varnyam (enhancement of color and complexion)
7. Grahapaham (protection from evil spirits and microorganisms)

How Shuvarnprashan works?

The three components of Shuvarnprashan work together towards enhancing the immunity and as each of them individually works on the betterment of immunity.

1. Gold
   1. It is an immuno-modulator (i.e. it reconstructs the immune system)
   2. Provides bal to the body
   3. Enhances life potency
   4. Enriches the texture of the skin
   5. Pharmacological studies showed specific and nonspecific immune responses, which were modified in a positive manner in Swarna Bhasma treated. It also had a stimulatory effect on peritoneal macrophages, which may be helpful to fight against infections.
   6. Note: It is evidently mentioned in the texts of Ayurveda that any form of gold should be used internally only after proper purification failing to do, which may result in complications that may be even life-threatening.The type of gold to be used, mode of administration of different forms, theirs benefits and therapeutic indications are also clearly explained
2. Cow Ghrit or Ghee
   1. Research indicates that phenolic antioxidants present in the ghee help in boosting the immune system
   2. It is rich in vitamin A & E, which help fight free radicals and promote good health
   3. CLA ( conjugated linolenic acid) in ghee lowers the level of bad cholesterol (low-density lipoprotein) and triglycerides in the body.
   4. Ghee also improves our vision by helping our bodies properly digest fat-soluble vitamins such as Vitamin A.
   5. It detoxifies the body by dissolving the toxins, which are then excreted out of the body through intestine. 
   6. Butyric acid, is the most important element in ghee, which has also been linked to the stimulation of T-cell production, which are the heavy hitting cells of the immune system. 
   7. The use of cow ghee can help supercharge your immune system.
   8. Dose shaman of Vata(वात) and Pitta(पित्त) Vikar (It balances the Vata and Pita dosha)
   9. Rasa, Shukra and Oja Vardhank ( Appharodiatic in nature and Improve Immunity)
   10. Sanskarasya Anuvartanam (Gives a boost to the potency of the medication)
   11. Twachya (Enhances the complexion of the skin)
   12. Dhee, Dhruti, Smruti, Medha vardhak ( Enhances the intellectual power of the brain)
   13. Agni Vardhak(Amplifies the digestive fire)
3. Honey
   1. Honey contains a protein made by bees called defensin-1, which is the most active germ killing ingredient in honey.
   2. It makes the penetration of other medicines easy.
   3. Easily palatable for children
   4. Contains high level of nutrients and glucose
   5. Chakshusya(चक्षुष्य) (Improves eyesight)
   6. Vishahara(वृष्य) (Aphrodisiac in nature)
   7. Rakta, Pittahara (रक्त & पित्तहर) ( Takes care of blood and pitta imbalance)

Research Findings

In a pharmaco-clinical study conducted on neonates Madhu-Ghrita-Swarna-Vacha Combination shows a significant effect on humoral antibody formation and it acted on immunological system, which was evident by triggering the response of immunological system by a rise in the total proteins and serum IgG levels.

Observations noted

1. The problems like bed wetting and indigestion are decreased
2. Reduced recurrency of frequent cough and cold. Reduced hospital visits
3. Hyperactive children become calm and it enhances concentration
4. Childrens are taking interest in study and sports
5. Shuvarnprashan increases immunity power in disorders like epileptic convulsion, allergy, Hepatitis-B
6. Improves speech

Things to note

1. Shuvarnprashan can be given to your child from childbirth till the age of 12 years.
2. Ideally, it should be given early in the morning on an empty stomach. Feed your child 30 minutes after giving Shuvarnprashan.
3. The specific benefits of Swarnaprashana according to the duration of administration have been mentioned such as:
   • If administered for 1 month, the baby will become Parama Medhavi (highly intelligent) and Vyadhibhir Na Cha Drusyate (will not be affected by any disease)
   • If administered for 6 months, the baby will become Srutadhara (will be able to remember the things, which are just heard).
   • You can follow a dosage for a period of 30 days. You may extend this till 180 days. Afterwards follow up on every pushyanaxatra(पुष्यनक्षत्र).
   • Your child should face the east side when taking this medicine. Shuvarnprashan is also known by other names such as Swarna amruta prashana, Swarna bindu prashana, Suvarna prashan, Swarna prashana and Swarnaprashan.

However, in conditions such as acute fever, swarnprashan can increase your body temperature. It is contraindicative in condition such as diarrhea, vomiting. Hence, it is important to consult an experienced and well-known Ayurveda practitioner before starting this Ayurveda process 

Tubulo-interstitial diseases of the kidney is a heterogeneous group of disorders affecting the kidney that share similar features of both tubular and interstitial injury. Primary categories of this disease includes, acute and chronic interstitial nephritis.

Acute interstitial nephritis is an acute form of kidney injury characterized by an inflammation reaction in the interstitial tissues of kidney and presence of edema, which usually spares the glomeruli. The hallmark of interstitial nephritis is the infiltration of inflammatory cells into the interstitial compartment. Infiltrating cells are mainly T cells and monocytes, plasma cells and eosinophils. An acute inflammatory reaction is most commonly caused by a hypersensitivity reaction of a drug.

Other causes include

• Infections
• Idiopathic or immune mediated
• Medications that most commonly cause allergic reactions are antibiotics (Ampicillin, Oxacillin)
• Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
• Proton pump inhibitors
• Bacteria implicated in causing this disease are Legionella, Brucella, Mycoplasma, Rickettsia, Leptospira and Chlamydia.
• There is a presence of swelling in between the kidney tubules.

Kidneys function to filter the circulating blood and remove toxins. Water and certain organic materials are re-absorbed from the filtered blood and unwanted products are released from the body via urine. Swelling of the tubules disrupts the normal filtration function of the kidneys. 

Symptoms 

• Most common symptom of interstitial nephritis is decreased urine output. It may increase in some cases. People can be symptomless in some cases. Other symptoms of interstitial nephritis include fever, presence of blood in urine, fatigue, mental confusion, nausea, vomiting, water retention and bloating sensation in the body.
• This disease does not have racial, age or gender predilection. It can affect anyone, of any age group. However, kidney toxicity depends on cumulative effects of toxic substances which means more the kidney is damaged due to toxic substances, the higher the risk of the kidney suffering from subsequent damage. With advancing age, the general functioning of the kidney is affected. This makes advanced age a risk factor for acute interstitial nephritis.

Clinical features

• Sudden decrement in the renal function is a typical presentation. It is most commonly seen in an asymptomatic patient or a patient who has been put on a new medication.
• It may occasionally present as renal failure.
• In the presence of an infection, a maculopapular rash, fever and eosinophilia are characteristically seen.
• Occurrence of skin rash >50 % of patients, fever > 75 % of patients and eosinophilia > 80% of patients.
• Pain in the lumbar and pelvic region.

Investigations:

• Presence of mild to moderate proteinuria
• Gross hematuria
• Sedimentation of red and white blood cells
• WBC casts, occasionally RBC casts are also present
• Increased serum creatinine levels
• Oliguria
• Confirmation of the diagnosis can be done by renal biopsy.

Treatment: Removal of the offending agents, discontinuation of the etiologic drug is the most important treatment modality. Complete recovery is inversely proportional to the duration of renal failure.
 

Chronic interstitial nephritis
The tubule cells undergo atrophy and there is a flattening of the epithelium. Basement membrane of tubules are frequently thickened. Cellular infiltrate is composed of lymphocytes, with only occasional neutrophils, plasma cells and eosinophils. There is a relative preservation of glomerular function until late in the disease, but an impairment of tubular functions like urine concentration, dilution, acidification and potassium excretion is seen early.