Search
Search
Common Specialities
Common Issues
Common Treatments

Overview

Creatinine Clearance Test

Creatinine Clearance Test

Creatinine clearance test is done in order to detect creatinine levels in the person. This in turn determines the working of kidneys. Creatinine is one of the waste products that is present in the urine. Presence of this material will help to know how well kidneys are functioning, blood flow and if there are any other disorders that will affect kidneys. This test will determine the rate of blood flow which is known as Glomerular Filtration Rate (GFR). This test is done by taking sample of urine for 24 hours or else sample of blood. GFR varies according to age, gender and size of the person.

In order to prepare for creatinine clearance test, it is better to take advice of the doctor beforehand. It is most important to doctor about the medicines or food you intake and know what should be avoided. Medicines such as pain killers, supplements and certain herbs should be avoided before the test is done. Also, it is essential to ask doctor at what time of the day should the test begin. In case of women, they are required to inform doctor beforehand if they are pregnant. Certain medicines can affect the creatinine levels, hence it is advisable to avoid the before the test on the advice of doctor. Even certain exercises will also affect GFR.

Creatinine clearance test results determine the level kidney disorders, depending upon the GFR levels. Hence, reports conclude following results: Kidney will be functioning normal if GFR is equal to 90 or above. If GFR is in between 60 to 89, then there is slight decrease in the functioning of kidneys. If GFR is in between 45 to 59, then there is mild to moderate decrease in the level of kidneys functioning. If GFR is in between 30 to 44, then there is moderate to severe decrease in functioning of kidneys. If GFR is in between 15 to 29, there is severe decrease in the level of kidneys functioning. If GFR is less than 15, it means are kidneys are failed and require immediate treatment.

Creatinine clearance test is used to detect the renal function and ability of kidneys to filter blood through them. This test is carried out in two types that is by taking sample of blood and other is taking sample of urine collected in 24 hours. Blood test is done by inserting needle into the vein and collecting sample blood from the person. This blood is transferred into tube and sent to laboratory. Urine test is done by taking sample of urine collected in 24 hours in the container. Person undergoing test need to empty is stomach in early morning without collecting the sample; from next time when they pass urine they need to collect it every time for 24 hours. Then this container has to be sent to laboratory for testing.

LimitationsWith reduced renal blood flow, creatinine rises less quickly than urea nitrogen. Concentration of creatinine only becomes abnormal when about half or more of the nephrons have stopped functioning in chronic progressive renal disease. Antibiotics containing cephalosporin lead to significant false-positive values if samples are drawn within four hours of a dose.4 With severe renal disease, creatinine is not reliable in the presence of cefoxitin therapy. There is less interference reported from the cephalosporins cephalothin, cephaloridine, cephadrine sodium, and cephaloglycin dihydrate. Lipemia, hemolysis, and bilirubin may interfere.5,6
Specimen
Serum (preferred) or plasma
Volume
1 mL
Container
Gel-barrier tube, red-top tube, green-top (heparin) tube, or lavender-top (EDTA) tube.
Type Gender Age-Group Value
Creatinine Clearance
Male
All age groups
97 to 137 ml/min
Creatinine Clearance
Female
All age groups
88 to 128 ml/min
Average price range of the test is between Rs.80 to Rs.400 depending on the factors of city, quality and availablity.

Table of Content

What is Creatinine Clearance Test?
Preparation for Creatinine Clearance Test
Uses of Creatinine Clearance Test
Procedure for Creatinine Clearance Test
Limitations of Creatinine Clearance Test
Specimen Requirements
Normal values for Creatinine Clearance Test
Price for Creatinine Clearance Test

Looking to go for this Lab Test?

Find out all the labs near you
Show Labs Near Me
Lybrate Gaurantee
Lybrate Gaurantee

Popular Questions & Answers

I had unprotected sex on 24th july and my period is due on 1st of august but I am still not feeling any period pain and my stomach is bloating feeling...

BHMS, MD - Homeopathy
Homeopathy Doctor, Vellore
I had unprotected sex on 24th july and my period is due on 1st of august but I am still not feeling any period pain a...
Dear lybrate-user! Wait for 10-15 days more and confirm the pregnancy. Sometimes the periods may delay after sexual contact.
4 people found this helpful

I am a student in 12th. I am under weighted and I can't afford costly Whey Proteins Powder. So How can I gain weight by cheap of Household methods?

BHMS
Homeopath, Secunderabad
I am a student in 12th. I am under weighted and I can't afford costly Whey Proteins Powder. So How can I gain weight ...
Do not worry too much. Just focus on eating healthy homemade food. A balanced diet is essential for the body to maintain ideal weight and overall health. Have milk and milk products. Try eating all types of beans (daals) which are a good source of natural proteins. You can search...
5 people found this helpful

My wife's health is low and weight is also low. She is 26 years old. I want that my wife should be in good shape. Please advise me sir.

BHMS
Homeopath, Secunderabad
My wife's health is low and weight is also low. She is 26 years old. I want that my wife should be in good shape. Ple...
See​ that she eats a balanced diet. She should also go for a routine medical check up just to ensure that there is no any health problem that remain undetected. Some basic tests are: CBC, ESR, blood sugar, thyroid test, urine routine, liver profile etc. She should also focus on e...
1 person found this helpful

My wife is 42 year old. She is suffering thyroid knot at right side. What type of medicine she should take. My nearest doctor suggest aloevera juice t...

MBBS, CCEBDM, Diploma in Diabetology, Diploma in Clinical Nutrition & Dietetics, Cetificate Course In Thyroid Disorders Management (CCMTD)
Endocrinologist, Dharwad
Mr. lybrate-user, Thanks for the query. First thing to be done is to do a Thyroid Function test, check the hormone levels and come back with the results. The swelling could be due to hypothyroidism or due to hyper activity. Plus there is a need to get ultra sonography of the glan...
3 people found this helpful

I have no child after my 4 years married life. I am under treatment since 2 yrs. The report of my anti mullerian hormone test is 1.27 NG/ML. Doctor to...

MD - Obstetrtics & Gynaecology, Fellowship in Infertility
IVF Specialist, Noida
I have no child after my 4 years married life. I am under treatment since 2 yrs. The report of my anti mullerian horm...
Hi. AMH of 2- 4 ng/ ml is optimum .However, this alone is not sufficient to arrive at a conclusion regarding the fertility status. We always co relate it with an ultrasound. Moreover. It is the egg number that can be commented upon and there is no test in the lab for egg quality ...
5 people found this helpful

Popular Health Tips

These Sexual Mistakes Compromise Penis Health!

MD - General Medicine
Sexologist, Delhi
These Sexual Mistakes Compromise Penis Health!
When it comes to maintaining proper penis health, most men have a very good idea of what to do. They know all the basics of penis care, from taking care to wash properly to regularly inspecting the manhood to applying a high-quality penis health crème. But in the heat of the mome...
21 people found this helpful

10 Signs You Might Be Suffering From Brain Tumor!

DNB NEUROSURGERY, M.B.B.S.
Neurosurgeon, Durgapur
10 Signs You Might Be Suffering From Brain Tumor!
A tumor is formed due to the uncontrolled proliferation of living cells. Generally, the cells in the human body continuously die and are replaced by new cells. Some cells are replaced frequently, like intestinal lining and skin, while some like nerve cells live longer and may not...
3122 people found this helpful

Peripheral Artery Disease!

MBBS, Dip.Cardiology, Fellowship in Clinical Cardiology(FICC), Fellowship in Echocardiology
Cardiologist, Ghaziabad
Peripheral Artery Disease!
Peripheral arterial disease (PAD) happens when there is a narrowing of the blood vessels outside of your heart. The cause of PAD is atherosclerosis. This happens when plaque builds up on the walls of the arteries that supply blood to the arms and legs. Plaque is a substance made ...
1 person found this helpful

Know More About Atheroslerosis!

MBBS, Dip.Cardiology, Fellowship in Clinical Cardiology(FICC), Fellowship in Echocardiology
Cardiologist, Ghaziabad
Know More About Atheroslerosis!
Atherosclerosis is a disease in which plaque builds up inside your arteries. Plaque is a sticky substance made up of fat, cholesterol, calcium, and other substances found in the blood. Over time, plaque hardens and narrows your arteries. That limits the flow of oxygen-rich blood ...
1 person found this helpful