Filaria (Lymphatic and Non - Lymphatic) Antibodies Test

Filariasis is a parasitic disease caused by roundworms. Depending on the area occupied by the parasites, the disease is divided into two types: Lymphatic and Non Lymphatic. Lymphatic Filariasis is targeted at the lymph nodes and lymph vessels in the body. Non Lymphatic Filariasis is targeted at the subcutaneous skin and fat layers of legs and genital areas. The body's immune system produces antibodies when any such harmful foreign body enters. This makes it easier to identify a particular parasite, by identifying the antibody associated with it. Filariasis induces an excess of IgG4 antibodies in the blood stream. If the patient shows symptoms of the disease, the doctor usually orders a blood test to detect presence of IgG4 in the blood.

No specific preparation is necessary. Inform the doctor of any medications being taken by the patient. It is recommended that the patient wear a short sleeved shirt.

The normal range of IgG4 antibodies in the blood stream is nearly 1. In case of a low range of IgG4, a patient showing symptoms will be directed towards a different test. In case of a high range of IgG4, the diagnosis is positive, but does not confirm Filariasis.. To enhance confirmation of this reading, an additional count of Eosinophils or IgM may be performed.

The blood sample will be drawn from a vein in the patient's arm. The site will be cleaned with an alcohol swab. A sterile needle will be inserted into the patient's arm. About 2ml of blood will be drawn from the arm of the patient. The site will be cleaned with a cotton swab.