HLA B 27, PCR Test

This test is performed to measure the level of HLA-B27 antigen in the blood. It helps to confirm Autoimmune Disorder, Bone Degeneration, Bone Inflammation and chronic pain. The test helps to diagnose the presence of HLA-B27 which is associated with certain autoimmune and immune-mediated diseases which may include: Ankylosing spondylitis: It causes inflammation of the bones in your spine. Reactive arthritis: It causes inflammation of the joints, urethra and eyes which may sometimes lesions on your skin. Juvenile rheumatoid arthritis could be diagnosed. Anterior uveitis: It causes swelling and irritation in the middle layer of the eye. Basically, the HLA-B27 tests may help to monitor all the progression of these and other autoimmune diseases.

No special preparation is needed for HLA-B27 test however it’s recommended to inform the doctor if any medications are on or have any underlying medical conditions or allergies before undergoing the test. Make sure to follow the doctor’s specific instructions.

The negative test indicates the absence of HLA-B27 in the blood. It’s good to remember that if the test is negative it doesn’t always mean that you don’t have an autoimmune disorder. Sometimes people with autoimmune disorders don’t have HLA-B27 on their white blood cells. If the test is positive then it means that HLA-B27 is present in the blood which may be a cause for concern, however the presence of the antigen doesn’t always mean that an autoimmune disorder will develop. While making the final diagnosis, all test results shall be considered along with the patient’s symptoms.

The HLA-B27 test involves a standard blood draw where the healthcare provider will usually take the blood sample from the patient’s arm using a small needle. Some patients may feel or experience discomfort when the blood is drawn and might feel pain at the puncture site during the test and mild pain or throbbing at the puncture site afterward. The blood is collected in a tube and sent to a lab for analysis.