Aciloc 150 MG Tablet

Aciloc Tablet is prescribed as the short-term treatment of active duodenal ulcers and benign gastric ulcers. This medicine is also prescribed for long-term prophylaxis of duodenal ulcer and gastric hypersecretory states, recurrent postoperative ulcer, prevention of acid-aspiration pneumonitis during surgery, and prevention of stress-induced ulcers; causes fewer interactions than cimetidine.

This medicine belongs to a drug group known as histamine (H2) receptor blocker. Aciloc 150 MG Tablet works by reducing the amount of acid produced in the stomach, effectively treating gastroesophageal reflux disease (GERD), Zollinger-Ellison syndrome and upper GI bleeding ulcers.

Patients need to be aware that intake of this medicine can increase the chances of succumbing to pneumonia. Its symptoms are pain in the chest, fever, coughing up slimy green snot and problems with breathing. Also, make sure that you are not allergic to this medication.

Make sure it is safe for you to consume this medication if you suffer from health problems like liver, kidney disease and porphyria. Although this medication does not really harm an unborn child, ensure that you tell your doctor if you are pregnant.

This medicine does pass into breast build, thus let your doctor know if you are taking this medication while breastfeeding too. It should be taken according to instructions given by the doctor. Do not change the dosage on your own.

Aciloc Tablet is meant for oral consumption and should be swallowed immediately. Do not chew or let the effervescent tablet dissolve after you place it in your mouth.

For instance, if you are taking 25 mg of it, dissolve it in 1 teaspoon of water. If you are taking 150 mg of this medicine, it should be dissolved in 6-8oz of water. It should be continued until the ulcer heals completely. Generally, it takes about 8 weeks for an ulcer to properly heal.

Take exactly as directed (at meals and bedtime); do not increase dose - may take several days before you notice relief. If antacids are approved by prescriber, allow 1 hour between antacid and Aciloc 150 MG Tablet.

Avoid OTC medications, especially cold or cough medication and aspirin or anything containing aspirin. Follow the diet as the prescriber recommends.

Symptoms of overdose include muscular tremors, vomiting, rapid respiration, renal failure, CNS depression. Treatment is primarily symptomatic and supportive.

Use with caution in children <12 years of age; use with caution in patients with liver and renal impairment; dosage modification required in patients with renal impairment; long-term therapy may cause vitamin B12 deficiency.

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• Duodenal Ulcer

  It is used for short term treatment of ulcers of the small intestine. It can also be used to prevent recurrence of ulcer in some patients.

• Gastric Ulcer

  Aciloc 150 MG Tablet is used for the short term treatment of stomach ulcers that are benign. It is also used as a maintenance therapy after the ulcers have healed.

• Gastroesophageal Reflux Disease

  It is used for the treatment of a condition where the acid produced in the stomach causes irritation in the food pipe.

• Erosive Esophagitis

  It is used for the treatment of a condition where the food pipe is eroded due to prolonged acid reflux from the stomach.

• Zollinger-Ellison Syndrome

  It is used to relieve the symptoms of this rare condition where the acid secretion in the stomach is abnormally high.

• Hypersecretory Condition

  It is used to prevent and treat conditions where the amount of acid secreted in the stomach is abnormally high.

• Allergy

  It is not recommended for use in patients who have a known history of allergy to Ranitidine (the primary constituent of medicine) or any other component of the medicine.

• Porphyria

  Aciloc 150 MG Tablet is not recommended for use in patients having this rare hereditary disease.

• Headache

• Dizziness

• Nausea Or Vomiting

• Diarrhoea

• Mental Confusion

• Difficulty In Breathing

• Gynecomastia

• Rash

• Sedation

• Arthralgia

• Fever

• How long is the duration of effect?

  The effect of Aciloc 150 MG Tablet lasts for an average duration of 6-8 hours.

• What is the onset of action?

  The effect of this medicine can be observed after an hour of oral administration.

• Are there any pregnancy warnings?

  Caution is advised while using this medicine during pregnancy. You should consult a doctor and use this medication only if the benefits outweigh the risks associated.

• Is it habit forming?

  No habit forming tendencies were reported.

• Are there any breast-feeding warnings?

  Caution is advised while using this medicine during pregnancy. You should consult a doctor and use this medication only if the benefits outweigh the risks associated.

• Does this affect kidney function?

  In case of renal impairment, doctor's consultation is a must before its administration. Dosing adjustment in renal impairment:

  • Clcr 10-50 mL/minute: Administer at 75% of normal dose or administer every 18-24 hours.
  • Clcr <10 mL/minute: Administer at 50% of normal dose or administer every 18-24 hours.
  • Hemodialysis: Slightly dialyzable (5% to 20%).

• Does this affect liver function?

  Patient must consult a doctor before taking this medication in case of liver impairment.

• Is It safe with alcohol?

  It is suggested not to take Aciloc 150 MG Tablet with alcohol, as it is unsafe to take it concomitantly.

• Is it safe to drive while on this medicine?

  Driving is usually safe if you are taking Aciloc 150 MG Tablet. As this medicine does not affect patients ability to drive.

Below is the list of medicines, which have the same composition, strength and form as Aciloc 150 MG Tablet , and hence can be used as its substitute.

• Zoran 150 MG Tablet

  Dr. Reddys Laboratories Ltd

• Zinetac 150 MG Tablet

  Glaxosmithkline Pharmaceuticals Ltd

• Ulfast 150 MG Tablet

  Sun Pharma Laboratories Ltd

• Peploc 150 MG Tablet

  Zydus Cadila

• Lampoz 0.25 MG Tablet

  Rusi Remedies P. Ltd

• Are there any missed dose instructions?

  Take the missed dose as soon as you remember. If it is almost time for the next scheduled dose, then the missed dose can be skipped.

• Are there any overdose instructions?

  Contact a doctor immediately if an overdose is suspected. Symptoms of overdose may include confusion, fainting, and lightheadedness.

It acts by inhibiting the action of histamine at specific H2 receptors present in the gastric parietal cells. Thus, gastric acid secretion process is inhibited.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  Avoid the consumption of alcohol while taking this medicine. Contact your doctor if you experience prolonged heartburn or presence of blood in the vomit or stools.

• Interaction with Lab Test

  False-positive urine protein, gastric acid secretion test, skin test allergen extracts, serum creatinine, and serum transaminase concentrations, urine protein test might appear. Thus before testing must inform your doctor that you are taking Aciloc 150 MG Tablet.

• Interaction with Medicine

  • It interacts with diazepam, lidocaine, phenytoin, propranolol and theophylline, Alteration of gastric pH, triazolam, midazolam, glipizide, ketoconazole, atazanavir, delavirdine, and gefitinib.
  • CYP2D6 and 3A3/4 enzyme inhibitor
  • Decreased toxicity of atropine
  • Increased toxicity of cyclosporine (increased serum creatinine), gentamicin (neuromuscular blockade), glyburide (increased concentrations), metoprolol, pentoxifylline, quinidine.

• Interaction with Disease

  Gastro-intestinal bleeding

  Use of this medication is not recommended for use if any symptoms indicating gastrointestinal bleeding exists. Consult your doctor if there is blood in vomit or the stools are bloody or black.

  Liver Disease

  Patients suffering from any kind of liver disease should not use Aciloc 150 MG Tablet.

  Porphyria

  This medication should be used with extreme caution in patients having a history of acute Porphyria.

• Ques : What is Aciloc 150 mg tablet?

  Ans : It is a medication which has ranitidine as an active ingredient present in it. This medicine performs its action by reducing the acid in the stomach which helps in relief of acid related indigestion and heartburn. It is a H2 blocker (antacid). It is used to treat conditions such as acidity, heartburn, stomach ulcers, etc.

• Ques : What is Aciloc 150 mg tablet used for?

  Ans : It is a prescribed medication which is used for the treatment, control, and prevention of conditions such as:

  1. Acidity
  2. GERD
  3. Sour burp
  4. Peptic ulcers
  5. Heartburn
  6. Indigestion during pregnancy
  7. Zollinger ellison syndrome

• Ques : What are the side effects of Aciloc tablet?

  Ans : It is a medication which has some known side effects. These side effects may or may not appears always and some of them are rare but severe. If you experience any of the below-mentioned side effects, contact your doctor immediately. Complete list of side effects caused by Aciloc tablet are as follows: Headache, depression, hallucination, mental confusion, nausea, sexual dysfunction, stomach discomfort, stomach pain, swelling of the skin, vertigo, nervousness, allergic reaction, blurred vision, chest pain, decreased, eosinophils, dizziness, enlarged breast, excessive production of milk, feeling of discomfort, hair, loss, hives, incomplete development of a tissue or organ, insomnia, involuntary motor, disturbances, joint pain, loss of interest in sexual activity, gastrointestinal disorders, hematologic, disorders, kidney disorder, etc.

• Ques : Can Aciloc be used to treat gastritis?

  Ans : Yes, Aciloc 150 mg tablet is a medication which can be used for the short-term treatment of gastritis. It works by reducing the acid released into the stomach and relieving stomach pain and acid reflux. It is a prescribed medication which should only be consumed on a prescription.

• Ques : How long do I need to use aciloc tablet before I see improvement of my conditions?

  Ans : This medication should be consumed, till the complete eradication of disease. Thus it is advised to use, till the time directed by your doctor and moreover taking this medication longer than it was prescribed, can also cause inadequate effect on the patient. So please consult your doctor.

• Ques : At what frequency do I need to use medicine ?

  Ans : This medication is generally used twice to thrice a day, as the time interval upto which this medication has an impact, is around 4 to 6 hours, but it is not the standard frequency, for using this medication. It is advised to consult your doctor for the dosage, as the frequency also depends on the patient's condition.

• Ques : Should I use aciloc tablet empty stomach, before food or after food?

  Ans : It is commonly taken orally from mouth and the action of salts involved in this medication, do not depend on using it pre-meal or post-meal. It is advised to consult a doctor before use and take it at a fixed time in a the day.

• Ques : What are the instructions for storage and disposal of aciloc tablet?

  Ans : It contains salts, which are suitable to store at room temperature and keeping this medication above or below that, can cause inadequate effect. Protect it from moisture and light. Keep this medication away, from the reach of children. It is advised to dispose the expired or unused medication, for avoiding its inadequate effect.

• Ques : Is Aciloc 150 MG Tablet banned?

  Ans : Food and Drug Administration (FDA), in 2020, requested that all forms of prescription & OTC ranitidine (Zantac) should be removed from the U.S. market.

• Ques : Why is this medication banned?

  Ans : This recommendation was made because unacceptable levels of NDMA, a probable carcinogen (cancer-causing chemical), were found. If you’re prescribed this medication then you must talk to your doctor about safe alternative options.

• Ques : Is this tablet an antacid?

  Ans : No. This medication works by reducing the amount of acid your stomach makes. Whereas, antacids neutralize the acid that your stomach has already made.

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  https://druginfo.nlm.nih.gov/drugportal/rn/66357-35-5

• Zantac Tablets 150mg- EMC [Internet]. www.medicines.org.uk. 2015 [Cited 25 April 2019]. Available from:

  https://www.medicines.org.uk/emc/product/219/smpc

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• RANITIDINE - ranitidine hydrochloride tablet- Daily Med [Internet]. dailymed.nlm.nih.gov. 2012 [Cited 25 April 2019]. Available from:

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