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Overview

Adapalene

Prescription vs OTC : Prescription by Doctor not required

About Adapalene

Used to treat acne, Adapalene belongs to a class of drugs called retinoids. It decreases the formation of blackheads and helps to renew skin faster. It helps to heal pimples quicker too by reducing skin inflammation and swelling.

If you are allergic to any of the ingredients of Adapalene, it is not be used. If you suffer from sunburn or eczema, its usage is not advised as well. Alert your doctor if you are allergic to Vitamin A drugs and other retinoid drugs such as isotretinoin.

The medicine is usually found in a cream form, and must not be applied to abrasions, cuts or sunburned skin. Avoid contact with eyes as it may cause redness and irritation. Adapalene may cause your skin to become sunburned easily, so it is advisable to limit your time in the sun.

Adapalene may cause some burning and stinging earlier on. Peeling, redness, scaling and dryness of skin may be seen too. Find medical attention immediately if you experience rashes, difficulty in breathing and swelling of face and lips.

For external use only. Apply with gloves in thin film at night to thoroughly clean/dry skin; avoid area around eyes or mouth. Do not apply occlusive dressing. Results make take 8-12 weeks to appear. You may experience transient burning or stinging immediately after applying.

Report worsening of condition or skin redness, dryness, peeling, or burning that persists between applications.

Apply once daily at bedtime; therapeutic results should be noticed after 8-12 weeks of treatment. Toxic signs of an overdose commonly respond to drug discontinuation, and generally return to normal spontaneously within a few days to weeks.

When confronted with signs of increased intracranial pressure, treatment with mannitol (0.25 g/kg I.V. up to 1 g/kg/dose repeated every 5 minutes as needed), dexamethasone (1.5 mg/kg I.V. load followed with 0.375 mg/kg every 6 hours for 5 days), and/or hyperventilation should be employed.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    What are the uses of Adapalene

    • Acne

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    What are the contraindications of Adapalene ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    What are the side effects of Adapalene ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    Key highlights of Adapalene

    • Is It safe with alcohol?

      No interaction found

    • Are there any pregnancy warnings?

      Adapalene may be unsafe to use during pregnancy.
      Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

    • Are there any breast-feeding warnings?

      Adapalene is probably safe to use during breastfeeding. Please consult your doctor.

    • Is it safe to drive while on this medicine?

      There is no data available. Please consult doctor before consuming the drug.

    • Does this affect kidney function?

      There is no data available. Please consult doctor before consuming the drug.

    • Does this affect liver function?

      There is no data available. Please consult doctor before consuming the drug.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    Medicines containing Adapalene

    Below is the list of medicines, which contains Adapalene as ingredient

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    How does this medication work?

    This medication works by mechanistically combining with certain retinoic acid nuclear receptors as well as retinoid X receptors. It does not combine with cytosolic receptor protein, however. The exact working nature of this medicine is not known.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

      What are the interactions of Adapalene ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Medicine

        This medication interacts with Salicylic Acid, Neuromuscular blockers, Isotretinoin.
      • Interaction with Disease

        Use with caution in patients with eczema; avoid excessive exposure to sunlight and sunlamps; avoid contact with abraded skin, mucous membranes, eyes, mouth, angles of the nose.

      FAQs about Adapalene

      • Ques : What is Adapalene?

        Ans : This medication contains Adapalene which belongs to the class named retinoid. This medicament is primarily prescribed to treat acne (Nodulocystic or Resistant acne).

      • Ques : How long do I need to use Adapalene before I see improvement in my condition?

        Ans : In most of the cases, the average time taken by this medication to reach its peak effect is around 1 day to 1 week. Please consult your doctor for the time period you need to use this medication.

      • Ques : At what frequency do I need to use Adapalene?

        Ans : This medication is generally applied at the affected area at the night. It is advised to consult your doctor before the usage, as the frequency also depends on the patient's condition.

      • Ques : Should I use Adapalene empty stomach, before food or after food?

        Ans : As this is a medicament to be applied externally. Thus it does not have any relation with the food intake.

      • Ques : What are the instructions for the storage and disposal of Adapalene?

        Ans : It should be stored at cool dark place, away from heat and direct light. Do not freeze. Keep it away from the reach of children and pets.

      References

      • Adapalene-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 10 June 2022].Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/adapalene

      • Adapalene-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 10 June 2022].Available from:

        https://go.drugbank.com/drugs/DB00210

      • ADAPALENE gel,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 10 June 2022].Available from:

        https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=ADAPALENE

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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