Af 150 MG Tablet DT

Af 150 MG Tablet DT is primarily prescribed for the treatment of hepatosplenic candidiasis and other Candida infections, cryptococcal infections and secondary prophylaxis for cryptococcal meningitis in persons with AIDS. It is also used as antifungal prophylaxis in allogeneic bone marrow transplant recipients.

This medicine belongs to the class of triazole antifungal. Af 150 MG Tablet DT is effectively used in the treatment of meningitis. It affects the membranes in the brain and spinal cord. This drug treats fungal infections like yeast infections in the mouth, throat, food pipe, lungs, vagina, etc.

It works by decreasing the production of ergosterol, which inhibits cell membrane formation in fungi. This drug is also preferred as a preventive medication in patients susceptible to fungal infections while undergoing chemotherapy or radiation therapy before bone marrow transplantation.

Some serious side effects that may occur and need immediate medical attention are:

• Yellowing of the skin, dark urine, light-coloured stool and itchiness of the skin, indicating liver damage
• Severe rash or peeling of the skin in patients suffering from cancer or AIDS
• Irregular or fast heart rate, palpitations, seizures or fainting, indicating Torsades de Pointes (a condition of abnormal rhythm of the heart which may cause a sudden cardiac arrest)

• Oropharyngeal Candidiasis

• Vaginal Candidiasis

• Fungal Infections (Tinea Strains)

• Cryptococcal Meningitis

• Coccidioidomycosis

• Hypersensitivity

• Decreased Appetite

• Insomnia

• Tremor

• Vertigo

• Constipation

• Dry Mouth

• Abdominal Pain

• Vomiting

• Diarrhoea

• Nausea

• Headache

• Rash

• Dizziness

• Hypokalemia

• How long is the duration of effect?

  The action of this drug in the body lasts for up to 30 hours after administration.

• What is the onset of action?

  This drug starts its action within a couple of hours after oral use.

• Are there any pregnancy warnings?

  This drug is extremely unsafe to be used during pregnancy. Studies carried out on humans and animals have shown significant adverse effects on the fetus. Doctor consultation is recommended in such cases.

• Is it habit forming?

  It does not have addictive tendencies.

• Are there any breast-feeding warnings?

  The drug should not be consumed by breastfeeding mothers as there is a higher risk of side-effects on the infant. You are suggested to consult your doctor to discuss the potential benefits and risks before taking this medicine.

• Does this affect kidney function?

  Dose adjustment is needed in patients with renal impairment. Consult your doctor before taking Af 150 MG Tablet DT.

• Does this affect liver function?

  No relevant information available. Consult your doctor before taking Af 150 MG Tablet DT.

• Is It safe with alcohol?

  Caution is advised in consuming alcohol, if you are taking this medicine. Please consult your doctor.

• Is it safe to drive while on this medicine?

  This medicine causes side effects that affect the alertness of the patients. Thus it influences the driving ability of the patient.

• Are there any missed dose instructions?

  Missed dose of this medication may be taken later unless it is already time for the next dose.

• Are there any overdose instructions?

  Seek emergency medical treatment or contact the doctor in case of an overdose.

This medication works by decreasing ergosterol production by disrupting the activity of cytochrome P450, inhibiting the formation of the cell membrane of susceptible fungi like Candida and Microsporum.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

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  Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

• Interaction with Lab Test

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  Keep monitoring periodic liver function tests (AST, ALT, alkaline phosphatase) and renal function tests, potassium. As these might drastically be affected by the action of the Af 150 MG Tablet DT.

• Interaction with Medicine

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  This drug interacts with Alprazolam, Atorvastatin, Clopidogrel, Cisapride, Warfarin, Terfenadine, Astemizole, Pimozide, Quinidine, Erythromycin, Halofantrine, Amiodarone, Rifampicin, Hydrochlorothiazide, Alfentanil, Amitriptyline, nortriptyline, Amphotericin B, Anticoagulants, midazolam, triazolam, Carbamazepine, Calcium channel blockers, Celecoxib, Cyclophosphamide, Fentanyl, Olaparib, Ciclosporin, Everolimus, Sirolimus, Tacrolimus, Losartan, Methadone, naproxen, lornoxicam, meloxicam, diclofenac, etc.

• Interaction with Disease

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  It is unsuitable for patients with QT prolongation and liver and kidney disorders.

• Interaction with Food

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  No data reported

• Ques : What is Af 150 MG Tablet DT?

  Ans : This drug decreases ergosterol production by disrupting the activity of cytochrome P450, inhibiting the formation of the cell membrane of susceptible fungi like Candida and Microsporum.

• Ques : How long do I need to use Af 150 MG Tablet DT before I see improvement in my condition?

  Ans : This medication should be consumed, until the complete eradication of the disease. Thus it is advised to use, till the time directed by your doctor. Also taking this medication longer than it was prescribed, can cause an inadequate effect on the patient's condition.

• Ques : At what frequency do I need to use Af 150 MG Tablet DT?

  Ans : The duration of effect for this medicine is dependent on the severity of the patient’s condition. Therefore the frequency of usage of this medication will vary from person to person. It is advised to follow the proper prescription of the doctor, directed according to the patient's condition.

• Ques : Should I use Af 150 MG Tablet DT empty stomach, before food or after food?

  Ans : This medication is advised to be consumed orally. The salts involved in this medication react properly if it is taken after having food. If you take it on an empty stomach, it might upset the stomach. Please consult the doctor before using it.

• Ques : What are the instructions for the storage and disposal of Af 150 MG Tablet DT?

  Ans : This medication contains salts which are suitable to store only at room temperature, as keeping this medication above or below that, can cause an inadequate effect. Protect it from moisture and light. Keep this medication away from the reach of children.

• Ques : Can Af 150 MG Tablet DT be taken with oral contraceptives (OCPs) or birth control pills?

  Ans : Af 150 MG Tablet DT may interact with oral contraceptives having ingredients like estradiol. Hence, consult a doctor before taking them together.

• Ques : I feel better now, can I stop taking Af 150 MG Tablet DT?

  Ans : It is important to finish the course of treatment, hence one must not stop taking this drug if they start feeling better. If you stop taking it without any doctor consultation, then it may severely affect your medical condition.

• Ques : Is Af 150 MG Tablet DT safe to be used in pregnancy?

  Ans : This drug is not suitable for pregnant women as it can harm the baby. Consult a doctor and use some other alternative to this drug.

• Ques : Can Af 150 MG Tablet DT cause hair loss?

  Ans : Hair loss is a very unusual side effect of this medicine. If you encounter this symptom, then doctor consultation is suggested.

• Ques : Is Af 150 MG Tablet DT fungistatic or fungicidal?

  Ans : Af 150 MG Tablet DT is a fungistatic medication and helps in inhibiting the growth or bacteria. It also functions as a fungicidal (kills fungus) medicine against some specific organisms.

• Ques : Is Af 150 MG Tablet DT over the counter (OTC)?

  Ans : No, this medication is not available as an over the counter (OTC) drug. You must only take it if this medicine is prescribed by a healthcare professional.

• Ques : What if I forget to take a dose of Af 150 MG Tablet DT?

  Ans : Take the missed dose as soon as possible, however, skip the missed dose if it is almost the time for the next dose.

• Ques : Is Af 150 MG Tablet DT effective?

  Ans : It is an effective medication, however, you must consume it in dose and duration suggested by a medical expert.

• Ques : Does Af 150 MG Tablet DT treat bacterial vaginosis?

  Ans : This drug is not helpful against bacterial vaginosis. If you are suffering from bacterial vaginosis, do not take this drug, rather talk to a doctor to start a treatment.

• Ques : Does Af 150 MG Tablet DT make you feel tired?

  Ans : Tiredness is a common side effect reported after consumption of this medicine. You may want to take rest after consuming this medicine.

• Ques : Is Af 150 MG Tablet DT a steroid?

  Ans : This medicine is not a steroid, in fact it is an antifungal drug.

• Ques : Can I take Af 150 MG Tablet DT for yeast infection?

  Ans : This medication can be taken for a yeast infection. Please consult a doctor before taking it.