Afdiloc 300Mg Tablet

Afdiloc 300Mg Tablet is prescribed as the short-term treatment of active duodenal ulcers and benign gastric ulcers. This medicine is also prescribed for long-term prophylaxis of duodenal ulcer and gastric hypersecretory states, recurrent postoperative ulcer, prevention of acid-aspiration pneumonitis during surgery, and prevention of stress-induced ulcers; causes fewer interactions than cimetidine.

This medicine belongs to a drug group known as histamine (H2) receptor blocker. Afdiloc 300Mg Tablet works by reducing the amount of acid produced in the stomach, effectively treating gastroesophageal reflux disease (GERD), Zollinger-Ellison syndrome and upper GI bleeding ulcers.

Patients need to be aware that intake of this medicine can increase the chances of succumbing to pneumonia. Its symptoms are pain in the chest, fever, coughing up slimy green snot and problems with breathing. Also, make sure that you are not allergic to this medication.

Make sure it is safe for you to consume this medication if you suffer from health problems like liver, kidney disease and porphyria. Although this medication does not really harm an unborn child, ensure that you tell your doctor if you are pregnant.

This medicine does pass into breast build, thus let your doctor know if you are taking this medication while breastfeeding too. It should be taken according to instructions given by the doctor. Do not change the dosage on your own.

This medication is meant for oral consumption and should be swallowed immediately. Do not chew or let the effervescent tablet dissolve after you place it in your mouth.

For instance, if you are taking 25 mg of it, dissolve it in 1 teaspoon of water. If you are taking 150 mg of this medicine, it should be dissolved in 6-8oz of water. It should be continued until the ulcer heals completely. Generally, it takes about 8 weeks for an ulcer to properly heal.

Take exactly as directed (at meals and bedtime); do not increase dose - may take several days before you notice relief. If antacids are approved by prescriber, allow 1 hour between antacid and Afdiloc 300Mg Tablet.

Avoid OTC medications, especially cold or cough medication and aspirin or anything containing aspirin. Follow the diet as the prescriber recommends.

Symptoms of overdose include muscular tremors, vomiting, rapid respiration, renal failure, CNS depression. Treatment is primarily symptomatic and supportive.

Use with caution in children <12 years of age; use with caution in patients with liver and renal impairment; dosage modification required in patients with renal impairment; long-term therapy may cause vitamin B12 deficiency.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

• Duodenal Ulcer

• Gastric Ulcer

• Hypersecretory Condition

• Gastroesophageal Reflux Disease

• Gastrointestinal Bleeding

• Other Forms Of Ulcers

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

• Allergy

  This medication is not recommended for use in patients who have a known history of allergy to Ranitidine (the primary constituent of Afdiloc 300Mg Tablet) or any other component of the medicine.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

• Headache

• Dizziness

• Nausea Or Vomiting

• Diarrhoea

• Mental Confusion

• Difficulty In Breathing

• Gynecomastia

• Rash

• Sedation

• Arthralgia

• Fever

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

• How long is the duration of effect?

  The effect of this medicine lasts for an average duration upto 8 hours.

• What is the onset of action?

  The effect of this medicine can be observed after an hour of oral or intravenous administration.

• Are there any pregnancy warnings?

  Caution is advised while using this medicine during pregnancy.

• Is it habit forming?

  No habit forming tendencies were reported.

• Are there any breast-feeding warnings?

  Caution is advised while using this medicine during pregnancy.

• Does this affect liver function?

  Patient must consult a doctor before taking this medication in case of liver impairment.

• Does this affect kidney function?

  In case of renal impairment, doctor's consultation is a must before its administration. Dosing adjustment in renal impairment:

  • Clcr 10-50 mL/minute: Administer at 75% of normal dose or administer every 18-24 hours.
  • Clcr <10 mL/minute: Administer at 50% of normal dose or administer every 18-24 hours.
  • Hemodialysis: Slightly dialyzable (5% to 20%).

• Is It safe with alcohol?

  It is suggested not to take Afdiloc 300Mg Tablet with alcohol, as it is unsafe to take it concomitantly.

• Is it safe to drive while on this medicine?

  Driving is usually safe if you are taking Afdiloc 300Mg Tablet. As this medicine does not affect patients ability to drive.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

Below is the list of medicines, which have the same composition, strength and form as Afdiloc 300Mg Tablet , and hence can be used as its substitute.

• Rantac Od 300Mg Tablet

  J B Chemicals and Pharmaceuticals Ltd

• Rancer 300Mg Tablet

  Micro Labs Ltd

• R Loc Forte 300Mg Tablet

  Zydus Cadila

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

• Missed Dose instructions

  Take the missed dose as soon as you remember. If it is almost time for the next scheduled dose, then the missed dose can be skipped.

• Are there any overdose instructions?

  Contact a doctor immediately if an overdose is suspected. Symptoms of overdose may include confusion, fainting, and lightheadedness.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

• India

• United States

• Japan

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

This medication acts by inhibiting the action of histamine at specific H2 receptors present in the gastric parietal cells. Thus, gastric acid secretion process is inhibited.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  Avoid the consumption of alcohol while taking this medicine. Contact your doctor if you experience prolonged heartburn or presence of blood in the vomit or stools.

• Interaction with Lab Test

  False-positive urine protein, gastric acid secretion test, skin test allergen extracts, serum creatinine and serum transaminase concentrations, urine protein test might appear. Thus before testing must inform your doctor that you are taking Afdiloc 300Mg Tablet.

• Interaction with Medicine

  Ketoconazole

  Report the use of either of the medicine to the doctor. The use of this medication tends to make Ketoconazole less effective. Inform the doctor if the symptoms do not improve or worsen. Do not discontinue the use of any medicine without consulting your doctor.

  Loperamide

  Report the use of either of the medicine to the doctor. Dose adjustment and safety monitoring may be needed when both these medicines are taken together. Your doctor may prescribe alternative medicine if your intake of Loperamide is very high or you suffer have a heart condition.

  Metformin

  Report the use of either of the medicine to the doctor. An adjustment in dose and more frequent monitoring of blood level are advised when these two medicines are taken together.

  Atazanavir

  Report the use of either of the medicine to the doctor. Your doctor may adjust the dosage of Atazanavir when it is to be consumed along with this medication. Do not stop the usage of any medication without consulting your doctor.

  Dasatinib

  Report the usage of either of the medications to the doctor. It is advised to replace one or both of these medicines with alternates that do not interact. Do not stop the usage of any medication without consulting the doctor.

  Pazopanib

  Report the use of either of the medicine to the doctor. Use of these two medications together should be avoided. Your doctor may prescribe suitable alternatives in such cases.

  Decreased toxicity of atropine.

  Increased toxicity of cyclosporine (increased serum creatinine), gentamicin (neuromuscular blockade), glipizide, glyburide, midazolam (increased concentrations), metoprolol, pentoxifylline, phenytoin, quinidine.

• Interaction with Disease

  Gastrointestinal Bleeding

  Use of this medication is not recommended for use if any symptoms indicating gastrointestinal bleeding exists. Consult your doctor if there is blood in vomit or the stools are bloody or black.

  Porphyria

  This medication should be used with extreme caution in patients having a history of acute Porphyria.

• Interaction with Food

  Information not available.

• Ques : What is Afdiloc 300Mg Tablet?

  Ans : This medication belongs to a drug group known as a histamine-2 blocker. The drug reduced the amount of acid produced in the stomach, effectively treating stomach and intestine ulcers.

• Ques : How long do I need to use Afdiloc 300Mg Tablet before I see improvement in my condition?

  Ans : This medication is to be taken till the time you see an improvement in your health conditions.

• Ques : At what frequency do I need to use Afdiloc 300Mg Tablet?

  Ans : The drug should be taken according to instructions given by the doctor. Do not change the dosage on your own.

• Ques : Should I use Afdiloc 300Mg Tablet empty stomach, before food or after food?

  Ans : This medication should be taken after food in a prescribed dosage.

• Ques : What are the instructions for the storage and disposal of Afdiloc 300Mg Tablet?

  Ans : This medication should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

• Ques : How long does it take for Afdiloc 300Mg Tablet to start working?

  Ans : This medication starts working as fast as 15 minutes from when it is given. Its effect is seen to last all day or all night.

• Ques : Can I consume alcohol with Afdiloc 300Mg Tablet?

  Ans : Alcohol does not interfere with the working of Afdiloc 300Mg Tablet. But, you should avoid taking alcohol as it may further damage the stomach, delaying your recovery.

• Ques : What are the serious side effects of Afdiloc 300Mg Tablet?

  Ans : Some of the serious side effects include hives, skin rash, itching, hoarseness and difficulty in breathing or swallowing.

• Ques : Is Afdiloc 300Mg Tablet safe for long-term use?

  Ans : There is limited data available on whether Afdiloc 300Mg Tablet can be used for the long term or not, but it is a relatively safe medicine. It is advised to consume Afdiloc 300Mg Tablet for the duration prescribed by your doctor.

• Ques : Is Afdiloc 300Mg Tablet effective?

  Ans : This drug would be effective only if used for the right indication in the dose and for the duration as advised by the doctor. It is advised to not to change the dose or stop consuming the drug without consulting your doctor.

• Ranitidine- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 12 December 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/rn/66357-35-5

• Ranitidine- DrugBank [Internet]. Drugbank.ca. 2019 [Cited 12 December 2019]. Available from:

  https://www.drugbank.ca/drugs/DB00863

• Ranicalm 75mg film-coated tablets- EMC [Internet] medicines.org.uk. 2016 [Cited 12 December 2019]. Available from:

  https://www.medicines.org.uk/emc/product/3462/smpc