Alprostadil

Alprostadil is used in the treatment of erectile issues in males. The drug is considered as a prostaglandin (PGE-1). Alprostadil increases the flow of blood to the penis as it relaxes some muscles and widen the blood vessels effectively. As the effect of Alprostadil starts to reduce the blood flow through the penis also decreases and the erection goes away.

The drug is not recommended for use if you suffer from the following problems such as-

• Allergy to any substance present in Alprostadil
• Problems with the bone marrow, priapism, leukemia, sickle cell anemia and an erection that is painful
• Penile implants, penis fibrosis and deformed penis
• Any injury or other physical issues that prevents you from having sexual intercourse

In order to ensure safety give your doctor a detailed medical history, and inform him about any current health issues that you are facing. Give him information about all the medication prescribed as well as non-prescribed that you are using. Also tell him about any allergies that you may have.

One of the side effects that you may experience while using Alprostadil is dizziness. Thus you must take precautionary measures to prevent any complications. Avoid driving or indulging in some strenuous activity to prevent any accidents. Alcohol consumption should be avoid or very limited, as alcohol can worsen the side effects.

Some general side effects of Alprostadil are painful erection, dizziness, fever, pain or burning in the urethra, apnea and flushing. You may very rarely experience a curved penis, and erections that lasts for a long period of time, development of a blood clot in the penis.

When taking Alprostadil you will need to go for regular check-ups and keep your doctor updated about your health at all times.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Uro before using this medicine.

• Erectile Dysfunction

  Alprostadil is used for the treatment of impotence; where achieving and sustaining an erection is a problem while having sexual intercourse. However, it will work only if there is sexual stimulation. It is also sometimes used for the diagnosis of erectile dysfunction.

• Patent Ductus Arteriosus

  This medicine is also used for the supportive treatment of a birth defect where a temporary blood vessel does not close soon after birth.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Uro before using this medicine.

• Allergy

  This medicine is not recommended for use if you have a known history of allergy to Alprostadil/Prostaglandins or any other ingredient present with it.

• Priapism

  This medicine is not recommended for use if you have prolonged and painful erection even in the absence of any stimulation. Certain conditions like Sickle cell anemia, leukemia, and Multiple myeloma may contribute to this condition and hence should not be used in such cases.

• Deformation Of Penis

  This medicine is not recommended for use if you have a deformed penis or have plaques due to a trauma (Peyronie's disease).

• Sexual Activity Not Recommended

  This medicine is not recommended for use if your doctor has advised to refrain from any sexual activity due to health reasons.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Uro before using this medicine.

• Pain And Burning Sensation In The Penis

  Urethral route/Intravenous route

• Urethral Bleeding

  Urethral route

• Testicular Pain

  Urethral route

• Headache

  Urethral route

• Dizziness

  Urethral route

• Increased Heart Rate

  Urethral route

• Prolonged And Painful Erection

  Intracavernosal route

• Hardening Of Penile Tissue

  Intracavernosal route

• Injection Site Bruising

  Intracavernosal route

• Swelling And Rashes At The Penile Region

  Intracavernosal route

• Bleeding At The Injection Site

  Intracavernosal route

• Swelling Of Veins

• Visual Disturbances

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Uro before using this medicine.

• How long is the duration of effect?

  The amount of time for which this medicine remains effective is subject to vary based on the intended use. However, this medicine is effective for 60-90 minutes when taken for erectile dysfunction.

• What is the onset of action?

  The amount of time taken for this medicine to show its effect is subject to vary depending on the intended use. The effect can be observed within 5-20 of administration when taken for erectile dysfunction.

• Are there any pregnancy warnings?

  This medicine is not recommended for use in pregnant women. Appropriate precautionary measures should be adopted if your partner is taking this medicine. Contact your doctor immediately if a pregnancy is suspected while your partner is using this medicine.

• Is it habit forming?

  No habit forming tendencies were reported.

• Are there any breast-feeding warnings?

  This medicine is not recommended for use in breastfeeding women.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Uro before using this medicine.

• Missed Dose instructions

  This medicine is taken on a need basis and hence a dosing regimen is highly unlikely.

• Are there any overdose instructions?

  Contact your doctor immediately if an overdose with this medicine is suspected. Symptoms may include fainting, feeling light-headed, prolonged and painful erection etc.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Uro before using this medicine.

• India

• United States

• Japan

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Uro before using this medicine.

Below is the list of medicines, which contains Alprostadil as ingredient

• Alpostin 500mcg Injection

  Samarth Life Sciences Pvt Ltd

• Bioglandin 500mcg Injection

  United Biotech Pvt Ltd

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Uro before using this medicine.

This medication acts by relaxing the arterial smooth muscles causing dilation of blood vessels in the penile region. It also relaxes the smooth muscles present in the ductus arteriosus in children with a congenital defect of the heart.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Uro before using this medicine.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

test

• Interaction with Alcohol

  Alcohol

  Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

• Interaction with Lab Test

  Lab

  Information not available.

• Interaction with Medicine

  Minoxidil

  Report the use of either of the medicine to the doctor. You may require a dose adjustment and frequent clinical monitoring to safely use this medicines together. Report any incidence of fainting, drowsiness, headache, and changed heart rate to the doctor.

  Sodium Nitrite

  Report the use of either of the medicine to the doctor. You may require close clinical monitoring while using these medicines together. Suitable precautionary measures should be taken to counter or manage the excessive lowering of blood pressure caused due to coadministration of these medicines.

  Sildenafil

  Report the use of either of the medicines to the doctor. You may experience a headache, drowsiness, fainting, and change in heart rate while using them together. Your doctor may determine the appropriate course of treatment in such cases.

  Riociguat

  Report the use of either of the medicine to the doctor. You may require a dose adjustment and more frequent monitoring of blood pressure levels while using them together. Report any incidence of a headache, drowsiness, fainting, and change in heart rate to the doctor.

  Pentoxifylline

  Report the use of either of the medicines to the doctor. You may experience a headache, drowsiness, fainting, and change in heart rate while using them together. Your doctor may determine the appropriate course of treatment in such cases.

  Papaverine

  Report the use of either of the medicine to the doctor. You may require a dose adjustment and more frequent clinical monitoring to safely use these medicines together. Do not stop the use of any medicine without consulting your doctor.

• Interaction with Disease

  Respiratory Disorders Of The Neonates

  This medicine should be used with extreme caution in newborn children having underdeveloped lungs. Suitable supportive measures like ventilation should be ensured before this medicine is used.

  Bleeding Disorders

  This medicine should be used with caution in patients having a bleeding disorder. Use of this medicine may cause adverse effects and may also worsen the bleeding problems.

• Interaction with Food

  Food

  Information not available.

• Alprostadil-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 7 June 2022].Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/alprostadil

• Alprostadil-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 7 June 2022].Available from:

  https://go.drugbank.com/drugs/DB00770

• ALPROSTADIL injection,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 7 June 2022].Available from:

  https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=ALPROSTADIL