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Overview

Amiloride

Prescription vs OTC : Prescription by Doctor required

About Amiloride

Being a potassium-sparing diuretic, Amiloride helps in lowering blood pressure and swelling by removing the extra water and electrolytes from the body without the loss of potassium.

This medicine is also prescribed to treat edematous conditions including CHF, hepatic cirrhosis, and hypoaldosteronism. Also, it is usually used in conjunction with more potent diuretics such as thiazides or loop diuretics.

For the first few days, this medication may make you feel dizzy, therefore, it is advised to not drive or do anything that requires concentration until you know how this medication affects you.

You must not consume potassium supplements and potassium-rich foods while you are on this drug. If you experience dizziness, diarrhoea, vomiting, fast or irregular heartbeat, swelling in feet, or difficulty breathing, immediately consult your doctor. Women who are pregnant and breastfeeding must also take doctor’s advice before consuming Amiloride.

Amiloride is contraindicated in patients with evidence of renal impairment or diabetes mellitus should not receive this medicine without close, frequent monitoring of serum electrolytes and renal function.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Physician before using this medicine.

    What are the uses of Amiloride

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Physician before using this medicine.

    What are the contraindications of Amiloride ?

    • Hypersensitivity

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Physician before using this medicine.

    What are the side effects of Amiloride ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Physician before using this medicine.

    Key highlights of Amiloride

    • How long is the duration of effect?

      This drug will remain active for about 24 hours.

    • What is the onset of action?

      The action of this drug will be initiated with 2 hours after its administration.

    • Are there any pregnancy warnings?

      Pregnant women are advised to consult a doctor before consuming this drug.

    • Is it habit forming?

      No, the medicine is not habit-forming or addictive.

    • Are there any breast-feeding warnings?

      Lactating mothers are advised to take medical help before consuming this medication.

    • Is it safe to drive while on this medicine?

      It is advisable that you do not indulge in driving while on this medication since there is a possibility of you experiencing drowsy or calm and thus affecting your driving skills.

    • Does this affect kidney function?

      No relevant information is available.

    • Does this affect liver function?

      No relevant information is available.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Physician before using this medicine.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      It is advisable that you do not miss a dosage since there is just one dose per day. Consume the missed dosage as soon as you remember.

    • Are there any overdose instructions?

      In case of an overdose, you may experience side effects like restlessness, anxiety, confusion or dizziness. In such cases, make sure that you consult a doctor with immediate effect.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Physician before using this medicine.

    Where is the Amiloride approved?

    • India

    • United States

    • Japan

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Physician before using this medicine.

    Medicines containing Amiloride

    Below is the list of medicines, which contains Amiloride as ingredient

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Physician before using this medicine.

    How does this medication work?

    This medication is a potassium-sparing diuretic that helps in lowering blood pressure and swelling. It removes the extra water and electrolytes from the body without the loss of potassium.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Physician before using this medicine.

      What are the interactions of Amiloride ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Lab Test

        Level of potassium (S) is increased while the patient is taking Amiloride.
      • Interaction with Medicine

        • Amoxicillin's absorption may be reduced; avoid concurrent use or observe for clinical response.
        • Angiotensin-converting enzyme inhibitors can cause hyperkalemia, especially in patients with renal impairment, potassium-rich diets, or on other drugs causing hyperkalemia; avoid concurrent use or monitor closely.
        • Potassium supplements may further increase potassium retention and cause hyperkalemia; avoid concurrent use.
        • Quinidine and amiloride together may increase risk of malignant arrhythmias; avoid concurrent use.
      • Interaction with Food

        This diuretic does not cause you to lose potassium; because salt substitutes and low-salt milk may contain potassium, do not use these products without checking with your physician, too much potassium can be as harmful as too little.
      • Interaction with Disease

        May cause hyperkalemia (patients with renal impairment, diabetes and the elderly are at greatest risk). Should be stopped at least 3 days before glucose tolerance testing. Use caution in severely ill patients in whom respiratory or metabolic acidosis may occur.

      FAQs about Amiloride

      • Ques : Is Amiloride safe for use in children?

        Ans : Amiloride is not recommended for children below the age of 18 as its safety and efficacy is not known.

      • Ques : How is Amiloride administered?

        Ans : Amiloride is absorbed in the body by oral administration.

      • Ques : What is the half-life of Amiloride?

        Ans : The half-life of Amiloride is between 6-9 hours.

      • Ques : What are the storage instructions of Amiloride?

        Ans : Amiloride is stored at room temperature in darkness.

      • Ques : What should be avoided while taking Amiloride?

        Ans : It is advised to not use salt-substitutes, high-salt diets as the former could increase potassium levels in the blood and the latter may cause water retention which makes the medicine less effective.

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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      Reviewed ByDr. Anil MehtaMBBS, DNB (General Medicine)General Physician
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