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Overview

Arsenox 10mg Injection

Manufacturer :  Intas Pharmaceuticals Ltd
Medicine Composition :  Arsenic Trioxide
Prescription vs OTC : Prescription by Doctor required

About Arsenox 10mg Injection

Arsenox 10mg Injection is used to treat acute promyelocytic leukemia, especially when other treatments such as chemotherapy have failed to work, or have stopped working after a certain period of time.

Before using this medication you need to tell your doctor:

  • if you have any allergies to any substances in the medicine
  • if you have a history of liver diseases, kidney diseases or diabetes
  • if you are allergic to the compound arsenic in itself

Additionally, this medication often causes a condition known as QT prolongation, which affects the rhythm of the heart, so your doctor has to know if you have a history of heart problems. You should also tell your doctor if you have low magnesium and potassium blood levels so that the medication does not trigger any unwanted side effects.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

    What are the uses of Arsenox 10mg Injection

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

    What are the contraindications of Arsenox 10mg Injection ?

    • Hypersensitivity

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

    What are the side effects of Arsenox 10mg Injection ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

    Key highlights of Arsenox 10mg Injection

    • Is It safe with alcohol?

      Interaction with alcohol is unknown. Please consult your doctor.

    • Are there any pregnancy warnings?

      This medication is unsafe to use during pregnancy.

    • Are there any breast-feeding warnings?

      This medication is probably unsafe to use during breastfeeding. Please consult your doctor.

    • Is it safe to drive while on this medicine?

      There is no interaction between driving and consuming this drug. So dose alteration is not needed.

    • Does this affect kidney function?

      There is no interaction between renal impairment and consuming this drug. So dose alteration is not needed.

    • Does this affect liver function?

      There is no data available. Please consult a doctor before consuming the drug.

    • What is the onset of action?

      The pharmacological action of this medication is initiated within 1 - 3 minutes after its administration.

    • How long is the duration of effect?

      It remain active for about 16 - 18 hrs after administration.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

    What are the substitutes for Arsenox 10mg Injection ?

    Below is the list of medicines, which have the same composition, strength and form as Arsenox 10mg Injection , and hence can be used as its substitute.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

    What are the dosage instructions?

    • Are there any overdose instructions?

      Seek emergency medical treatment or contact the doctor in case of an overdose.

    • Are there any missed dose instructions?

      If you miss a dose of this medication, please consult your doctor.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

    How does this medication work?

    This medicine causes death of cancerous cells by altering the morphology and by DNA fragmentation in NB4 human leukemia cells. It also destroys fusion protein PML/RAR-alpha. The utility of this drug, however, still under study.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

      What are the interactions of Arsenox 10mg Injection ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Medicine

        This medication interacts with diuretics or amphotericin B, macrolide, and antipsychotic thioridazine

      FAQs about Arsenox 10mg Injection

      • Ques : What is Arsenox 10mg Injection?

        Ans : This medication is used to treat acute promyelocytic leukaemia, especially when other treatments such as chemotherapy have failed to work, or have stopped working after a certain period of time.

      • Ques : How long do I need to use Arsenox 10mg Injection before I see improvement in my condition?

        Ans : This medication is to be taken till the time you see an improvement in your health conditions.

      • Ques : At what frequency do I need to use Arsenox 10mg Injection?

        Ans : This medication should be taken in the dosage as prescribed by the doctor.

      • Ques : Should I use Arsenox 10mg Injection empty stomach, before food or after food?

        Ans : This medication should be taken after food in a prescribed dosage.

      • Ques : What are the instructions for the storage and disposal of Arsenox 10mg Injection?

        Ans : This medication should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

      References

      • Arsenic trioxide- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 10 December 2019]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/rn/1327-53-3

      • Arsenic trioxide- DrugBank [Internet]. Drugbank.ca. 2019 [Cited 10 December 2019]. Available from:

        https://www.drugbank.ca/drugs/DB01169

      • Arsenic Trioxide (TRISENOX) 1mg/ml concentrate for solution for infusion- EMC [Internet] medicines.org.uk. 2015 [Cited 10 December 2019]. Available from:

        https://www.medicines.org.uk/emc/product/5377/smpc

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Content Details
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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