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Overview

Asparaginase

Prescription vs OTC : Prescription by Doctor required

About Asparaginase

Asparaginase, a chemotherapy drug, is used to treat acute lymphoblastic leukaemia. It also treats several other blood disorders. It works by breaking down a chemical in cancer cells which stops the cancer cells from growing and dividing. This medicine is given as an injection into a vein or as an injection under the skin.

Some common side effects of this medicine are fever, chills, nausea and vomiting, allergic reactions, poor appetite, stomach cramps, excessive sleepiness, hallucinations, depression, agitation, disorientation or seizure.

Before starting this medicine, inform your doctor about any other medications you are taking and whether you are pregnant or not. Do not breast feed while taking this medication. People with a history of pancreatitis and hypersensitivity to this drug should not take it. Do not receive any kind of vaccination without your doctor's approval while taking this medicine.

The amount, procedure, duration and frequency of Asparaginase that you should take will be determined by your doctor based on your height and weight, health problems, and the type of cancer or condition being treated. 

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

    What are the side effects of Asparaginase ?

    • Breathlessness

    • Rash

    • Vomiting

    • Angioedema

    • Nausea

    • Fatigue

    • Increased Liver Enzymes

    • Edema (Swelling)

    • Diarrhoea

    • Decreased Blood Pressure

    • Flushing

    • Decreased Albumin Level In Blood

    • Increased Glucose Level In Blood

    • Urticaria

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

    Key highlights of Asparaginase

    • Is It safe with alcohol?

      Interaction with alcohol is unknown. Please consult your doctor.

    • Are there any pregnancy warnings?

      Bionase 5000iu injection may be unsafe to use during pregnancy.
      Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

    • Are there any breast-feeding warnings?

      Bionase 5000iu injection is probably unsafe to use during breastfeeding. Please consult your doctor.

    • Is it safe to drive while on this medicine?

      Caution is advised when driving or operating machinery.

    • Does this affect kidney function?

      There is no interaction between renal impairment and consuming this drug. So dose alteration is not needed.

    • Does this affect liver function?

      There is no data available. Please consult doctor before consuming the drug.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

    Medicines containing Asparaginase

    Below is the list of medicines, which contains Asparaginase as ingredient

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

    How does this medication work?

    The active constituent of this medication is used to treat acute lymphoblastic leukaemia. It is a non-essential amino acid that retains DNA, RNA and protein synthesis and encourages the growth of the cell, some of the core activities that cancerous cells cannot perform.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Oncologist before using this medicine.

      References

      • Asparaginase-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 10 June 2022].Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/asparaginase

      • Asparaginase-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 10 June 2022].Available from:

        https://go.drugbank.com/drugs/DB00023

      • ASPARAGINASE injection,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 10 June 2022].Available from:

        https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=ASPARAGINASE

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Content Details
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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