Aspirin 75 MG Tablet

Aspirin 75 MG Tablet belongs to the group of medications called analgesics (pain relievers), antipyretics (fever reducers), anti-inflammatories (inflammation reducers), and platelet aggregation inhibitors (anticlotting agents).

This medicine is also prescribed for prophylaxis for myocardial infarction and transient ischemic episodes. It works by interfering with the production of compounds in the body that cause pain, fever, inflammation, and blood clots.

Aspirin 75 MG Tablet is used to treat pain, and reduce fever or inflammation. This medicine is also used in the management of rheumatoid arthritis, rheumatic fever, osteoarthritis, and gout (high dose). It is sometimes used to treat or prevent heart attacks, strokes, and chest pain (angina).Aspirin should be used for cardiovascular conditions only under the supervision of a doctor.

Stop using this medicine and call your doctor at once if you have:

• ringing in your ears, confusion, hallucinations, rapid breathing, seizure (convulsions)
• severe nausea, vomiting, or stomach pain
• bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds
• fever lasting longer than 3 days
• swelling, or pain lasting longer than 10 days.

Common uses of Aspirin 75 MG Tablet include headaches, period cramps, colds and flu, sprains and strains, and long-term conditions, such as arthritis.For mild to moderate pain, it is used alone. For moderate to severe pain, it is often used along with other opioid analgesic and NSAIDs.

If self-administered, use exactly as directed (do not increase dose or frequency); adverse reactions can occur with overuse. Take with food or milk. Do not use aspirin with strong vinegar-like odor. Do not crush or chew extended release products. Aspirin 75 MG Tablet should be avoided by the person who are/have :

• a peptic ulcer
• Hemophilia or any other bleeding disorder
• a known allergy to aspirin
• an allergy to any NSAID, such as ibuprofen
• at risk of gastrointestinal bleeding or hemorrhagic stroke
• drink alcohol regularly
• undergoing dental or surgical treatment

In case of overdosage/toxicology, treatment should also be based upon symptomatology. Toxic symptoms and corresponding treatments are as follows:

• Overdose: Induce emesis with ipecac, and/or lavage with saline, followed with activated charcoal.
• Dehydration: I.V. fluids with KCl (no D5W only).
• Metabolic acidosis (must be treated): Sodium bicarbonate.
• Hyperthermia: Cooling blankets or sponge baths.
• Coagulopathy/hemorrhage: Vitamin K I.V.
• Hypoglycemia (with coma, seizures, or change in mental status): Dextrose 25 g I.V.
• Seizures: Diazepam 5-10 mg I.V.

While using this medication, avoid alcohol, excessive amounts of vitamin C, or salicylate-containing foods (curry powder, prunes, raisins, tea, or licorice), other prescription or OTC medications containing aspirin or salicylate, or other NSAIDs without consulting prescriber. Maintain adequate hydration (2-3 L/day of fluids unless instructed to restrict fluid intake).

• Mild To Moderate Pain

• Inflammation

• Rheumatic Fever

• Fever

• Rheumatoid Arthritis

• Osteoarthritis

• Gout

• Hypersensitivity

• Asthma

• Rhinitis

• Bleeding Disorders

• Pregnancy

• Hypotension

• Edema (Swelling)

• Rash

• Urticaria

• Dehydration

• Nausea

• Vomiting

• Heartburn

• Duodenal Ulcer

• Anemia

• Weakness

• Tinnitus

• Bronchospasm

• Anaphylaxis

• Is It safe with alcohol?

  Taking Aspirin with alcohol increases the associated risk of stomach bleeding.

• Are there any pregnancy warnings?

  Aspirin 75 MG Tablet is unsafe to use during pregnancy.
  There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.

• Are there any breast-feeding warnings?

  Aspirin 75 MG Tablet is probably usafe to use during lactation. \nLimited human data suggests that the drug could represent a significant risk to the baby.

• Is it safe to drive while on this medicine?

  Aspirin 75 MG Tablet may make you feel dizzy, drowsy or affect your vision. Do not drive until your vision is clear.

• Does this affect kidney function?

  Aspirin 75 MG Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Aspirin 75 MG Tablet may not be needed in these patients. Please consult your doctor.

• Does this affect liver function?

  Aspirin 75 MG Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Aspirin 75 MG Tablet may not be needed in these patients. Please consult your doctor.

• How long is the duration of effect?

  The effect of this medicine will last for about 4 to 6 hours.

• What is the onset of action?

  The effect is initiated within 15 - 30 minutes after its administration.

Below is the list of medicines, which have the same composition, strength and form as Aspirin 75 MG Tablet , and hence can be used as its substitute.

• Asa 75 MG Tablet

  Zydus Cadila

• E Prin 75 MG Tablet

  Torrent Pharmaceuticals Ltd

• Ecosprin 75 MG Tablet

  Usv Ltd

• Loprin 75 MG Tablet

  Unichem Laboratories Ltd

• Sprin 75 MG Tablet

  Alkem Laboratories Ltd

• Are there any overdose instructions?

  Seek emergency medical treatment or contact the doctor in case of an overdose.

• Are there any missed dose instructions?

  If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Aspirin 75 MG Tablet is a drug very commonly used to treat fever, pain and inflammation. The drug inactivates the cyclooxygenase, which is required for the synthesis of prostaglandins and thromboxane.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

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  Combination causes GI irritation, possible bleeding; avoid or limit alcohol. Patients at increased risk include those prone to hypoprothrombinemia, vitamin K deficiency, thrombocytopenia, thrombotic thrombocytopenia purpura, severe hepatic impairment, and those receiving anticoagulants.

• Interaction with Others

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  • Folic acid: Hyperexcretion of folate; folic acid deficiency may result, leading to macrocytic anemia. Supplement with folic acid if necessary.
  • Iron: With chronic aspirin use and at doses of 3-4 g/day, iron deficiency anemia may result; supplement with iron if necessary.
  • Sodium: Hypernatremia resulting from buffered aspirin solutions or sodium salicylate containing high sodium content. Avoid or use with caution in CHF or any condition where hypernatremia would be detrimental.
  • Curry powder, paprika, licorice, Benedictine liqueur, prunes, raisins, tea and gherkins: Potential salicylate accumulation. These foods contain 6 mg salicylate/100 g. An ordinarily American diet contains 10-200 mg/day of salicylate. Foods containing salicylates may contribute to aspirin hypersensitivity. Patients at greatest risk for aspirin hypersensitivity include those with asthma, nasal polyposis or chronic urticaria.
  • Fresh fruits containing vitamin C: Displaces drug from binding sites, resulting in increased urinary excretion of aspirin. Educate patients regarding the potential for a decreased analgesic effect of aspirin with consumption of foods high in vitamin C.

• Interaction with Lab Test

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  False-negative results for glucose oxidase urinary glucose tests (Clinistix®); false-positives using the cupric sulfate method (Clinitest®); also, interferes with Gerhardt test, VMA determination; 5-HIAA, xylose tolerance test and T3 and T4.

• Interaction with Medicine

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  • ACE inhibitors: The effects of ace inhibitors may be blunted by aspirin administration, particularly at higher dosages.
  • Buspirone increases aspirin's free % in vitro.
  • Carbonic anhydrase inhibitors and corticosteroids have been associated with alteration in salicylate serum concentrations.
  • Heparin and low molecular weight heparins: Concurrent use may increase the risk of bleeding.
  • Methotrexate serum levels may be increased; consider discontinuing aspirin 2-3 days before high-dose methotrexate treatment or avoid concurrent use.
  • NSAIDs may increase the risk of gastrointestinal adverse effects and bleeding. Serum concentrations of some NSAIDs may be decreased by aspirin.
  • Platelet inhibitors (IIb/IIa antagonists): Risk of bleeding may be increased.
  • Probenecid effects may be antagonized by aspirin.
  • Sulfonylureas: The effects of older sulfonylurea agents (tolazamide, tolbutamide) may be potentiated due to displacement from plasma proteins. This effect does not appear to be clinically significant for newer sulfonylurea agents (glyburide, glipizide, glimepiride).
  • Valproic acid may be displaced from its binding sites which can result in toxicity.
  • Verapamil may potentiate the prolongation of bleeding time associated with aspirin.
  • Warfarin and oral anticoagulants may increase the risk of bleeding.

• Interaction with Disease

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  • Use with caution in patients with platelet and bleeding disorders, renal dysfunction, dehydration, erosive gastritis, or peptic ulcer disease.
  • Avoid use in severe renal failure or in severe hepatic failure.
  • Discontinue use if tinnitus or impaired hearing occurs.
  • Caution in mild-moderate renal failure (only at high dosages).
  • Patients with sensitivity to tartrazine dyes, nasal polyps and asthma may have an increased risk of salicylate sensitivity.
  • Surgical patients should avoid ASA if possible, for 1-2 weeks prior to surgery, to reduce the risk of excessive bleeding.

• Interaction with Food

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  May decrease the rate but not the extent of oral absorption. Drug may cause GI upset, bleeding, ulceration, perforation. Take with food or large volume of water or milk to minimize GI upset.

• Ques : What is Aspirin 75 MG Tablet used for?

  Ans : Aspirin 75 MG Tablet is used in the treatment of pain, and to reduce fever or inflammation, It is also sometimes used to treat or prevent cardiovascular health conditions.

• Ques : What is the onset of action of Aspirin 75 MG Tablet?

  Ans : Aspirin 75 MG Tablet takes approximately 5 to 30 minutes to show its effect.

• Ques : How long does the effect of Aspirin 75 MG Tablet last?

  Ans : The effect of Aspirin 75 MG Tablet lasts between 4 to 6 hours.

• Ques : Where is Aspirin 75 MG Tablet approved?

  Ans : Aspirin 75 MG Tablet is approved in India, Micronesia, Japan, and the USA.

• Ques : Should Aspirin 75 MG Tablet be taken with a meal or without a meal?

  Ans : Aspirin 75 MG Tablet can be taken either as its effectiveness does not depend on a meal.

• Ques : Is Aspirin 75 MG Tablet safe for asthma patients?

  Ans : Aspirin 75 MG Tablet is not recommended for usage in asthma patients.

• Ques : Is Aspirin 75 MG Tablet safe for usage in patients with gastrointestinal disorders?

  Ans : Aspirin 75 MG Tablet is not recommended for usage in patients with gastrointestinal disorders as it can worsen their health conditions.