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Overview

Axogurd Nt Tablet Sr

Manufacturer :  Alembic Pharmaceuticals Ltd
Medicine Composition :  Pregabalin, Nortriptyline
Prescription vs OTC : Prescription by Doctor not required

About Axogurd Nt Tablet Sr

Axogurd Nt Tablet Sr is a combination medication prescribed for the treatment of severe neuropathic pain. It is also used for the management of neuropathic disorders like diabetic peripheral neuropathy, postherpetic neuralgia, and spinal cord injury.

It works by binding to a certain region of the brain and reducing the pain signals sent out by the damaged nerves of the body. This medicine is also utilised for treating restless leg syndrome, epilepsy, shingles, seizures, fibromyalgia and generalised anxiety disorder.

This medication is not recommended for you if you are pregnant, or have an allergic reaction towards any of its ingredients. Some medicines interact with it. Inform your doctor if you are taking any of the following:

  • Angiotensin- converting enzyme inhibitors
  • Benzodiazepines or narcotic pain medicines
  • Thiazolidinedione antidiabetic agents

Ensure your doctor is informed if you have any of the following medical conditions before starting the medication:

  • If you have congestive heart failure, irregular heartbeat, diabetes, bleeding problems, muscle problems, highballed pressure or low platelet count.
  • If you have improper kidney functioning or are on dialysis.
  • If you have a history of angioedema.
  • If you are pregnant, planning to be pregnant or are breastfeeding.
  • If you take any other medicines, dietary supplements or herbal preparations.
  • If you have mental or mood problems, suicidal thoughts, or are dealing with depression.

The dose for this medication may vary according to the age, sex, pathological conditions and other factors. The dosage can later be increased depending on efficacy and tolerability of the patient.

    What are the uses of Axogurd Nt Tablet Sr

    • Neuropathic Pain

    • Diabetic Peripheral Neuropathy

    • Postherpetic Neuralgia

    What are the contraindications of Axogurd Nt Tablet Sr ?

    What are the side effects of Axogurd Nt Tablet Sr ?

    Key highlights of Axogurd Nt Tablet Sr

    • How long is the duration of effect?

      The effect of this medicine lasts for an average duration of 10-12 hours.

    • What is the onset of action?

      This medicine has a varying onset time depending on the intended use.

    • Are there any pregnancy warnings?

      This medicine should be avoided by pregnant women unless suggested by the doctor.

    • Is it habit forming?

      This medicine has a low abuse potential with limited physical and psychological dependence.

    • Are there any breast-feeding warnings?

      The medicine should not be consumed by breastfeeding mothers as there is a higher risk of side-effects on the infant.

    What are the substitutes for Axogurd Nt Tablet Sr ?

    Below is the list of medicines, which have the same composition, strength and form as Axogurd Nt Tablet Sr , and hence can be used as its substitute.

    What are the dosage instructions?

    • Missed Dose instructions

      Take the missed dose as soon as you remember. If it is almost time for the next scheduled dose then the missed dose can be skipped.

    • Are there any overdose instructions?

      Contact your doctor immediately if an overdose is suspected. Symptoms of overdose may include agitation, mental confusion, excessive drowsiness.

    How does this medication work?

    This medication is a combination of Pregabalin and Nortriptyline, thus work through a dual mechanism of action. Primarily, it behaves as a GABA analogue and binds to the voltage-gated calcium channels in the central nervous system. This causes a reduced release of neurotransmitters like serotonin, dopamine, substance P thus slowing down nerve signals. Secondarily, it blocks the serotonin reuptake at the neuronal membrane. Also, it inhibits the reuptake of norepinephrine and raises its concentration in the synaptic cleft.

      FAQs about Axogurd Nt Tablet Sr

      • Ques : What is Axogurd Nt Tablet Sr?

        Ans : This medication is a combination of Pregabalin and Nortriptyline and is considered to be the first-line of treatment for neurotic pain, shingles, seizures and fibromyalgia.

      • Ques : What are the Side Effects of Axogurd Nt Tablet Sr?

        Ans : Here are some side effects of Axogurd Nt Tablet Sr which are as follows: Constipation, Difficulty in urination, Weight gain, Sleepiness, Dizziness, Tiredness, Blurred vision, Dryness in the mouth, Increased heart rate, Orthostatic hypotension, and Uncoordinated body movements.

      • Ques : What are the instructions for storage and disposal Axogurd Nt Tablet Sr?

        Ans : This tablet should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

      • Ques : Should I use Axogurd Nt Tablet Sr empty stomach, before food or after food?

        Ans : This medication is common to be taken orally. The action of salts involved in this medication, do not depend on whether taking it pre-meal or post-meal.

      • Ques : How long do I need to use Axogurd Nt Tablet Sr before I see improvement of my conditions?

        Ans : In most of the cases, the average time taken by this medication to reach its peak effect is around 1 to 2 weeks, before noticing an improvement in the condition.

      • Ques : Is there any food or drink I need to avoid?

        Ans : If you are under the usage of this medication, It is recommended to avoid grapefruit juice, as it may cause some side effects.

      • Ques : Will Axogurd Nt Tablet Sr be more effective if taken in more than the recommended dose?

        Ans : There is no need to take this medication more than its recommended doses. Taking an overdose of this medication may trigger side effects.

      References

      • Nortriptyline- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 23 January 2020]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/pregabalin

      • Pregabalin- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 23 January 2020]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/nortriptyline

      • Nortriptyline 10 mg Film-coated Tablets [Internet]. medicines.org.uk 2019 [Cited 23 January 2020]. Available from:

        https://www.medicines.org.uk/emc/medicine/32962

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Content Details
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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