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Bencid 500mg Tablet

Manufacturer :  Geno Pharmaceuticals Ltd
Medicine Composition :  Probenecid
Prescription vs OTC : Prescription by Doctor required

About Bencid 500mg Tablet

Bencid 500mg Tablet helps in the prevention of gouty arthritis; hyperuricemia; prolongation of beta-lactam effect (ie, serum levels). It is advised to take the dose as prescribed by the doctor.

You must immediately stop using Bencid 500mg Tablet and inform your doctor if you notice a rash, dizziness, itching, sore gums, painful urination, etc. Women who are pregnant or breastfeeding must take medical help before consuming this drug.

Use Bencid 500mg Tablet with caution in patients with peptic ulcer. Use extreme caution in the use of Bencid 500mg Tablet with penicillin in patients with renal insufficiency. Bencid 500mg Tablet may not be effective in patients with a creatinine clearance <30 to 50 mL/minute; may cause exacerbation of acute gouty attack.

Symptoms of overdose of Bencid 500mg Tablet include nausea, vomiting, tonic-clonic seizures, coma. Use activated charcoal is especially effective at binding Bencid 500mg Tablet, for GI decontamination.

Take as directed; do not discontinue without consulting prescriber. May take 6-12 months to reduce gouty attacks (attacks may increase in frequency and severity for the first few months of therapy).

Take with food or antacids or alkaline ash foods (milk, nuts, beets, spinach, turnip greens). Maintain adequate hydration (2-3 L/day of fluids unless instructed to restrict fluid intake). Avoid aspirin, or aspirin-containing substances. Diabetics should use serum glucose monitoring.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    What are the uses of Bencid 500mg Tablet

    • Gouty Arthritis

    • Increased Uric Acid Level In Blood

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    What are the contraindications of Bencid 500mg Tablet ?

    • Hypersensitivity

    • Peptic Ulcer

    • Renal Impairment

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    What are the side effects of Bencid 500mg Tablet ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    Key highlights of Bencid 500mg Tablet

    • Are there any pregnancy warnings?

      Pregnant women are advised to consult a doctor before consuming this drug.

    • Are there any breast-feeding warnings?

      Lactating mothers are advised to take medical help before consuming this medication.

    • Is it habit forming?

      No, the medicine is not habit-forming or addictive.

    • Does this affect kidney function?

      Caution must be taken in patient with kidney disease. Adjustment of the dose is needed. Kindly consult your doctor before taking this medicine.Avoid use of Bencid 500mg Tablet in patients with renal impairment (Clcr <50 mL/minute).

    • Does this affect liver function?

      Relevant information is not available. Please consult to know if any dose adjustment is needed in patients with liver impairment.

    • How long is the duration of effect?

      The drug remain active for about 6-12 hours and is dose dependent.

    • What is the onset of action?

      Effect on penicillin levels reached in about 2 hours

    • Is it safe to drive while on this medicine?

      You are advised to start driving after taking the help of the medical practitioner.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    What are the dosage instructions?

    • Are there any overdose instructions?

      In case of an overdose, you may experience side effects like restlessness, anxiety, confusion or dizziness. In such cases, make sure that you consult a doctor with immediate effect.

    • Are there any missed dose instructions?

      It is advisable that you do not miss a dosage since there is just one dose per day. Consume the missed dosage as soon as you remember.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    Where is the Bencid 500mg Tablet approved?

    • India

    • United States

    • Japan

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    How does this medication work?

    Competitively inhibits the reabsorption of uric acid at the proximal convoluted tubule, thereby promoting its excretion and reducing serum uric acid levels; increases plasma levels of weak organic acids (penicillins, cephalosporins, or other beta-lactam antibiotics) by competitively inhibiting their renal tubular secretion.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

      What are the interactions of Bencid 500mg Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Alcohol

        Using alcohol while taking this drug is not recommended. Any activity requiring a high level of mental alertness should be avoided in such cases.
      • Interaction with Lab Test

        False-positive glucosuria with Clinitest®, a falsely high determination of theophylline has occurred and the renal excretion of phenolsulfonphthalein 17-ketosteroids and bromsulfophthalein (BSP) may be inhibited.
      • Interaction with Medicine

        Decreased effect:
        • Salicylates (high dose) may decrease uricosuria.
        • Nitrofurantoin may decrease efficacy.
        Increased toxicity:
        • Increases methotrexate toxic potential; combination with diflunisal has resulted in 40% decrease in its clearance and as much as a 65% increase in plasma concentrations due to inhibition of diflunisal metabolism.
        • Bencid 500mg Tablet decreases the clearance of beta-lactams such as penicillins and cephalosporins; increases levels/toxicity of acyclovir, thiopental, clofibrate, dyphylline, pantothenic acid, benzodiazepines, rifampin, sulfonamide, dapsone, sulfonylureas, and zidovudine.
        • Avoid concomitant use with ketorolac (and other NSAIDs) since its half-life is increased twofold and levels and toxicity are significantly increased.
        • Allopurinol readministration may be beneficial by increasing the uric acid lowering effect.
        • Pharmacologic effects of penicillamine may be attenuated.
      • Interaction with Food

        Drug may cause GI upset; take with food if GI upset. Drink plenty of fluids.

      FAQs about Bencid 500mg Tablet

      • Ques : What are the uses of Bencid 500mg Tablet?

        Ans : Bencid 500mg Tablet is used to treat gout arthritis and gout. Bencid 500mg Tablet helps in reducing the amount of uric acid in the body by passing it through urine.

      • Ques : Is it safe to use Bencid 500mg Tablet in patients with a history/active uric acid kidney stones?

        Ans : It is advised to not use Bencid 500mg Tablet in a patient with a history/active case of uric acid kidney stone as it may worsen its condition.

      • Ques : What is the route of elimination of Bencid 500mg Tablet?

        Ans : Bencid 500mg Tablet is excreted in urine as an unchanged drug and monoacyl glucuronide, the alkalinity of the drug increases the elimination of Bencid 500mg Tablet.

      • Ques : What is the half-life of Bencid 500mg Tablet?

        Ans : The half-life of Bencid 500mg Tablet is between 6 to 12 hours.

      • Ques : Should Bencid 500mg Tablet be taken with a meal or without a meal?

        Ans : Bencid 500mg Tablet is more effective when taken with a meal, additionally, it reduces irritation.

      • Ques : Where is Bencid 500mg Tablet approved?

        Ans : Bencid 500mg Tablet is approved in India, Japan, and the USA.

      • Ques : What are the storage instructions of Bencid 500mg Tablet?

        Ans : Bencid 500mg Tablet should be approved at room temperature in dark away from light and moisture in its original packaging.

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Content Details
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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