Carbetocin

Carbetocin is indicated for prevention of postpartum bleeding due to uterine atony. This medicine is also used in nasal preparation used to promote milk letdown in lactating females.

This medicine is an analogue of a famous hormone called Carbetocin is called- the love hormone due to its characteristic feature of affecting human behaviour and to induce empathy, love, generosity, sexual inclination and bonding in them.

This medicine actually increases calcium in the muscle cells that influence uterus contraction, hence it is actually used to help in causing contraction in the uterus thereby facilitating the delivery. Carbetocin is also used to help mothers with breastfeeding and to stimulate milk production.

Carbetocin is a safe medicine when used in the proper dosage. Some of the side effects of this medicine which are reported are increased blood pressure, increased or decreased heart rate, changes in uterine blood flow, nausea and vomiting, allergic reactions ranging from mild to severe, any rupture in the uterus.

Long term or systemic administration of Carbetocin may result in impairment of memory retrieval process as well. This medicine shouldn’t be used if your birth canal is too narrow or small, or the fetus is in a difficult position in the wound and is in distress.

Carbetocin is intended for use by experienced and qualified staff for obstetrics care.The use of Carbetocin at any stage before delivery of the infant is not appropriate because its uterotonic activity persists for several hours. This is in marked contrast to the rapid reduction of effect observed after discontinuation of an Carbetocin infusion.

In case of persistent uterine bleeding after administration of Carbetocin, the cause must be determined. Consideration should be given to causes such as retained placental fragments, perineal, vaginal and cervix lacerations, inadequate emptying or repair of the uterus in case of caesarean section, or disorders of blood coagulation.

Carbetocin is intended for single administration only, intramuscular or intravenous. In case of intravenous administration it must be administered slowly over 1 minute. In case of persisting uterine hypotonia or atony and the consequent excessive bleeding, additional therapy with another uterotonic should be considered. There is no data on additional doses of Carbetocin or on the use of Carbetocin following persisting uterine atony after Carbetocin.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.

• Prevention of postpartum haemorrhage due to uterine atony

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.

• Pregnancy and labour before delivery of the infant

• Must not be used for induction of labour

• Renal or hepatic disorders

• Serious cardiovascular disorders

• Epilepsy

• Hypersensitivity

  Hypersensitivity to active substance, oxytocin or one of the excipients according to the composition.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.

• Nausea Or Vomiting

• Headache

• Slow Heart Rate

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.

• Are there any pregnancy warnings?

  Carbetocin is highly unsafe to use during pregnancy. Human and animal studies have shown significant adverse effects on the foetus. Please consult your doctor.

• Are there any breast-feeding warnings?

  Unknown. Human and animal studies are not available. Please consult your doctor.

• Is It safe with alcohol?

  Interaction with alcohol is unknown. Please consult your doctor.

• Is it safe to drive while on this medicine?

  Caution is advised when driving or operating machinery. Women with uterine contractions should not drive or use machines.

• Does this affect kidney function?

  There is no data available. Please consult a doctor before consuming the drug.

• Does this affect liver function?

  There is no data available. Please consult a doctor before consuming the drug.

• What is the onset of action?

  The onset of action of this medicine is within 2 min after its intravenous administration.

• How long is the duration of effect?

  This medicine will remain active for about 60 minutes after its administration.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.

• India

• United States

• Japan

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.

Below is the list of medicines, which contains Carbetocin as ingredient

• Caritec Solution for Injection

  Sun pharmaceutical ind. Ltd.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.

The pharmacological and clinical properties of Carbetocin are those of a long acting oxytocin agonist. Like oxytocin, Carbetocin selectively binds to oxytocin receptors in the smooth muscle of the uterus, stimulates rhythmic contractions of the uterus, increases the frequency of existing contractions, and raises the tone of the uterus musculature. On the postpartum uterus, Carbetocin is capable of increasing the rate and force of spontaneous uterine contractions. The onset of uterine contraction following Carbetocin is rapid after intravenous or intramuscular administration, with a firm contraction being obtained within 2 minutes.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Medicine

  Sympathomimetic pressor effects may be increased by Carbetocin resulting in postpartum hypertension.

• Ques : What is Carbetocin?

  Ans : Carbetocin is a Carbetocin is a synthetic long acting analog of oxytocin which Stable at room temperature ( 300C ) & 75% relative humidity.

• Ques : For what Carbetocin is used for?

  Ans : As a medicine, Carbetocin is used to minimize the bleeding after childbirth (postpartum hemorrhage).

• Ques : How and in what dose can Carbetocin be used?

  Ans : It is given as an injection by the medical healthcare professional. The dose is decided by the doctor, depending on the contraction pattern or the current medical situation of the patient.

• Ques : Is there any special precaution should I follow, while taking Carbetocin?

  Ans : Your medical practitioner would take the proper medical history, and evaluate you before giving this medicine. You should tell your medical history to your doctor.

• Ques : What may be the possible side effects associated with Carbetocin use?

  Ans : Side effects may include headache, nausea, vomiting, and increased blood pressure. You may also feel increased uterine contractions for some time.

• Ques : What are the instructions for storage and disposal Carbetocin?

  Ans : Store at up to 30°C. Do not freeze. Keep the vials in the outer carton, in order to protect from light.