Cefipime

Cefipime is used for treating certain bacterial infections that include pneumonia and skin, kidney as well as urinary tract infections. It can be combined with other medications for treating infections in the abdominal area. Belonging to the drug group known as cephalosporin antibiotics, Cefipime is also used in treating patients with high fever having a greater risk of an infection, due to the low white blood cell count. The medication kills the bacteria, thus preventing the infection from spreading in the body. It is administered by an injection into a vein or a muscle, as instructed by your doctor. It is available in powder form that can be mixed with liquid and also in a pre-mixed liquid form.

The dosage of Cefipime depends on your overall health condition, the infection you are suffering from and your body’s reaction to the first dose. In case you are taking this medication at home, ensure that you have complete knowledge regarding the preparation and usage. Continue using it till the time you have been prescribed by the doctor, even if you feel that you are getting better. Stopping it abruptly in the middle of the course can result in the returning of the infection. Also, do not take two doses to make up if you have missed a dose previously.

Cefipime may have some side effects like headache, diarrhea and pain, redness or swelling in the area where it has been injected. You can wait for the symptoms to go away or consult your doctor if it bothers you. In case of the following serious side effects, seek medical help at once:

• Watery stools with blood, stomach cramps and fever
• Rashes
• Difficulty in swallowing and breathing
• Seizures, confusion or hallucinations
• Signs of liver problem like nausea, vomiting, stomach pain, loss of appetite
• Yellowing of your eyes and the skin

In case you are pregnant or planning to be, or a breastfeeding mother, consult your doctor before taking Cefipime.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• Pneumonia

  Cefipime is used in the treatment of community-acquired pneumonia which is a common type of lung infection caused by Streptococcus pneumoniae and Haemophilus influenzae.

• Pyelonephritis

  Cefipime is used in the treatment of Pyelonephritis which is a type of kidney infection caused by E.coli, Pseudomonas aeruginosa, Enterococci and Klebsiella pneumoniae.

• Skin And Soft Tissue Infections

  Cefipime is used to treat skin and soft tissue infections caused by Staphylococcus aureus and Streptococcus pyogenes.

• Intra-Abdominal Infections

  Cefipime is used in the treatment of intra-abdominal infections caused by Helicobacter pylori, Staphylococci and Streptococci.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• Allergy

  Avoid if you have a known allergy to Cefipime or any other Beta-lactam antibiotics like penicillins or cephalosporins.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• Abdominal Pain

• Bleeding Gums

• Convulsions

• Fever

• Headache

• Yellow Colored Eyes Or Skin

• Swelling Of Foot

• Diarrhoea

• Redness Of Skin

• Pain At The Injection Site

• Itching Of Vagina Or Genital Area

• Sore Mouth

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• How long is the duration of effect?

  The effect of this medicine lasts for an average duration of 6 hours.

• What is the onset of action?

  The peak effect of this medicine can be observed in 0.5 to 1.5 hours after an intravenous dose and 1 to 2 hours after an intramuscular dose.

• Are there any pregnancy warnings?

  This medicine is not known to cause any harm to the fetus. But the evidence is inadequate and it should be used only when necessary after consulting a doctor.

• Is it habit forming?

  No habit forming tendency has been reported.

• Are there any breast-feeding warnings?

  This medicine is safe to use during breastfeeding. Any incidence of rashes on skin or diarrhea in the infant should be reported. It is advised to consult a doctor before taking this medicine.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• Missed Dose instructions

  The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.

• Are there any overdose instructions?

  Seek emergency medical treatment or contact the doctor in case of overdose.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

• India

• United States

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

Below is the list of medicines, which contains Cefipime as ingredient

• Mapime 500 MG Injection

  Mapra Laboratories Pvt. Ltd

• Orpime 500 MG Injection

  Orchid Chemicals & Pharmaceuticals Ltd

• Cepime 500 MG Injection

  Alembic Ltd

• Scud 250 MG Injection

  Zuventus Healthcare Ltd

• Sefdin 500 MG Injection

  Unichem Laboratories Ltd

• Megapime 500 MG Injection

  Alkem Laboratories Ltd

• Forpar 500 MG Injection

  Cipla Ltd

• Novapime 250 MG Injection

  Lupin Ltd

• Kefpime 500 MG Injection

  Macleods Pharmaceuticals Pvt.Ltd

• Novapime 500 MG Injection

  Lupin Ltd

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

Cefipime belongs to the fourth generation cephalosporins. It works as a bactericidal by inhibiting the bacterial cell wall synthesis by binding to the penicillin-binding proteins which would inhibit the growth and multiplication of bacteria.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  Alcohol

  Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

• Interaction with Lab Test

  Lab

  Information not available.

• Interaction with Medicine

  Amikacin

  You may experience nausea or vomiting, increased or decreased urination, sudden weight gain, and fluid retention if these medicines are used together. This interaction is more likely to occur if you have a kidney disease. Regular kidney function tests are to be performed and appropriate dose adjustments or replacement of the medicine should be made under the doctor's supervision.

  Ethinyl Estradiol

  The desired effect of contraceptive pills will not be achieved if these medicines are taken together. Appropriate dose adjustments or replacement of the medicine should be made under the doctor's supervision.

  Cholera Vaccine

  You should avoid taking Cholera vaccine for atleast 14 days after taking Cefipime. Usage of other antibiotics and vaccines should be reported to the doctor.

  Furosemide

  You may experience nausea or vomiting, increased or decreased urination, sudden weight gain, and fluid retention if these medicines are used together. This interaction is more likely to occur in the elderly population with preexisting kidney disease. Regular kidney function tests are to be performed and appropriate dose adjustments or replacement of the medicine should be made under the doctor's supervision.

• Interaction with Disease

  Impaired Kidney Function

  The blood concentration of intravenous Cefipime may increase in the patients suffering from impaired kidney function. Suitable dose adjustments are to be made based on the severity of the condition. Frequent monitoring of kidney function tests is necessary.

  Colitis

  Avoid if you experience severe diarrhea, abdominal pain, and blood in stools after taking Cefipime. Inform the doctor if you are suffering from any gastrointestinal diseases. Drink adequate amount of water to prevent dehydration.

  Impaired Liver Function

  Use with caution if you have any liver disease or a family history of liver disease. Regular liver function tests are to be performed. Inform the doctor if you have any liver disease or if you develop any undesired effect.

  Seizure Disorders

  Use with caution if you have any seizure disorder or a family history of seizures. Appropriate dose adjustments are to be made if you are suffering from a kidney disease. Discontinue if seizure is due to Cefipime. Start with appropriate anticonvulsant medicine if it is clinically indicated.

• Interaction with Food

  Food

  Information not available.

• Cefepime-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 1 June 2022].Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/cefepime

• Cefepime-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 1 June 2022].Available from:

  https://go.drugbank.com/drugs/DB01413

• CEFEPIME injection,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 1 June 2022].Available from:

  https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=CEFEPIME