Cholestyramine

Cholestyramine, a bile acid sequestrant, is a strong ion exchange resin which binds bile within the alimentary canal and prevents its reabsorption. It forms insoluble complexes with bile acids and removes from them from the body during defecation. In order to compensate for the lost bile acids from the body, more plasma cholesterol gets converted to bile acids in the liver and hence reduces plasma cholesterol levels.

Cholestyramine is used to treat problems like hypercholesterolemia, pruritus (itching due to liver failure), post vagotomy diarrhoea, Clostridium difficile infections, post cholecystectomy syndrome, Crohn's disease, bile acid diarrhoea and other types of cholestasis. Cholestyramine is sometimes compounded with aquaphor and used for treating diaper rash in infants.

Cholestyramine is marketed as powder for oral ingestion, in 4g packets, or in larger containers and the dosage is 4 to 8g once twice daily. The maximum dosage is 24g per day.

Side effects of Cholestyramine include tarry stools, constipation, sudden loss in weight, stomach ache, bloating, belching, nausea, vomiting, indigestion, headache, dizziness, diarrhoea, femoral nerve pain, vertigo, muscle and joint pain, arthritis, osteoporosis, osteomalacia, urticaria (in cases of hypersensitivity), diuresis, hematuria, dysuria, asthma and others.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

• Increased Cholesterol Levels In Blood

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

• Constipation

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

• Is It safe with alcohol?

  Interaction with alcohol is unknown. Please consult your doctor.

• Are there any pregnancy warnings?

  Choltran oral suspension may be unsafe to use during pregnancy.
  Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

• Are there any breast-feeding warnings?

  Unknown. Human and animal studies are not available. Please consult your doctor.

• Is it safe to drive while on this medicine?

  There is no data available. Please consult doctor before consuming the drug.

• Does this affect kidney function?

  There is no data available. Please consult doctor before consuming the drug.

• Does this affect liver function?

  There is no data available. Please consult doctor before consuming the drug.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

• Are there any missed dose instructions?

  If you miss a dose of Cholestyramine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

Below is the list of medicines, which contains Cholestyramine as ingredient

• Choltran Oral Suspension

  Ajanta Pharma Ltd

• Clostran 9gm Sachet

  Medi-Globe Corporation

• Choltran 5mg Tablet

  Ajanta Pharma Ltd

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

Cholestyramine acts as a bile acid sequestrant. It works by combining with the bile acids in the gastrointestinal tract, thereby preventing their reabsorption in the blood and thus reducing LDL cholesterol.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

test

• Interaction with Medicine

  Encorate Syrup

  null

  Zydol 50Mg Suspension

  null

  LASIX 40MG/4ML INJECTION

  null

  VALOX 500MG TABLET CR

  null

• Cholestyramine-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 9 June 2022].Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/cholestyramine

• Cholestyramine-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 9 June 2022].Available from:

  https://go.drugbank.com/drugs/DB01432

• CHOLESTYRAMINE tablet,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 9 June 2022].Available from:

  https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=CHOLESTYRAMINE