Cifran 500 MG Tablet

Cifran 500 MG Tablet is an antibiotic that is a member of the quinolone family of medicines. It is effective in treating infections that are caused by bacteria. Cifran 500 MG Tablet is used to treat patients with bacterial infections such as pneumonia, anthrax, syphilis, gonorrhea, bronchitis, gastroenteritis and plague.

This antibiotic is also used to fight against infections of the throat, skin, ears, nose, sinus, bones, respiratory system and urinary tract. Cifran 500 MG Tablet inhibits the regular synthesis of bacterial DNA, obstructing the process of their cell division. Therefore, it destroys the existing bacteria that are causing the infection, and it inhibits the growth of new bacteria.

Cifran 500 MG Tablet is an anti-biotic, which is a member of the fluoroquinolone family. It helps fight against infections caused by bacteria. It is used to treat severe bacterial infections including pneumonia, respiratory or urinary tract infections, gonorrhoea, anthrax, gastroenteritis as well as infections of the sinus, bones, skin and joints. It is also effective in treating septicemic plague.

Cifran 500 MG Tablet works by destroying the existing bacteria, that cause infection, from within the body and preventing the growth of new bacteria. The regular synthesis of DNA requires the presence of enzymes of bacterial DNA gyrase and topoisomerase IV.

Cifran 500 MG Tablet inhibits the activity of DNA gyrase, thus preventing DNA relaxation, encouraging the damage of double-stranded DNA and inhibiting the cell division of bacteria. In this way, Cifran 500 MG Tablet is efficient in fighting against bacterial infections within the body.

It is important to read the label of this medicine and follow the exact guidelines of the doctor’s prescription. Do not take an extra pill to make up for a missed dose, if you forget to take a dose. Instead, just continue with the next dose.

If you are allergic to Cifran 500 MG Tablet, you will experience rashes, hives, breathing problems, swelling of the throat, tongue, face or limbs and itchiness. If you notice these symptoms, it is advisable to stop taking this medicine immediately and contact your doctor.

In some cases, patients having certain disorders, who take this antibiotic, are more susceptible to its side effects. Therefore, before starting a prescription of this medicine, you should consult the doctor if you are allergic to Cifran 500 MG Tablet, blood disorders, conditions of the heart and low levels of magnesium in the blood.

Children and pregnant women should exercise caution before taking this medication. Although this antibiotic does treat infections, it does not treat infections like influenza, cold and viral infections.

• Bacterial Infections

• Lower Respiratory Tract Infection

• Urinary Tract Infection

• Prostatitis

• Allergy

• Cns Stimulation

• Discoloration Of Teeth

• Headache

• Restlessness

• Nausea

• Diarrhoea

• Vomiting

• Abdominal Pain

• Rash

• Dizziness

• Confusion

• Seizures

• Anemia

• Increased Liver Enzymes

• Tremor

• Arthralgia

• Acute Renal Failure

• How long is the duration of effect?

  Cifran 500 MG Tablet remains active in the body up to 24 hours after administration and is excreted in the urine.

• What is the onset of action?

  Cifran 500 MG Tablet is rapidly absorbed from the Gastro-intestinal tract and reaches its peak levels after 2 to 2.5 hours of oral administration.

• Are there any pregnancy warnings?

  Cifran 500 MG Tablet is considered safe for consumption by pregnant women. But there is a lack of conclusive evidence and hence, it must be used only when necessary after consulting a Doctor. Potential benefits and risks involved should be considered before taking the drug.

• Is it habit forming?

  No habit forming tendencies were reported.

• Are there any breast-feeding warnings?

  Cifran 500 MG Tablet is not expected to cause any adverse effects on the breastfed baby. However, a Doctor must be consulted before taking the drug.

• Is It safe with alcohol?

  Consumption of alcohol with this medicine does not cause any harmful side effects.

• Is it safe to drive while on this medicine?

  This medicine may affect the alertness of the patient, thus driving must be avoided if you are taking this medication.

• Does this affect kidney function?

  Caution must be taken in patient with kidney disease. Adjustment of the dose might be needed. Consult your doctor before taking this medication.

• Does this affect liver function?

  This medicine is probably found to be safe to use in patients with liver disease. Limited information is available to suggest dose adjustment in these patients. Kindly consult your doctor for further information.

• Are there any missed dose instructions?

  The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.

• Are there any overdose instructions?

  Seek emergency medical treatment or contact your doctor in case of an overdose.

Cifran 500 MG Tablet belongs to the class fluoroquinolones. It works as a bactericidal by inhibiting the bacterial DNA gyrase enzyme, which is essential for DNA replication, transcription, repair, and recombination. This leads to expansion and destabilization of the bacterial DNA and causes cell death.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Medicine

  • CYP1A2 enzyme inhibitor
  • Enteral feedings may decrease plasma concentrations of Cifran 500 MG Tablet probably by >30% inhibition of absorption. Cifran 500 MG Tablet should not be administered with enteral feedings. The feeding would need to be discontinued for 1-2 hours prior to and after Cifran 500 MG Tablet administration. Nasogastric administration produces a greater loss of Cifran 500 MG Tablet bioavailability than does nasoduodenal administration.
  • Aluminum/magnesium products, didanosine, and sucralfate may decrease absorption of Cifran 500 MG Tablet by greater than or equal to 90% if administered concurrently.
  RECOMMENDATION: Administer Cifran 500 MG Tablet 2 hours before dose OR administer Cifran 500 MG Tablet at least 4 hours and preferably 6 hours after the dose of these agents OR change to an H2-antagonist or omeprazole.
  • Calcium, iron, zinc, and multivitamins with minerals products may decrease absorption of Cifran 500 MG Tablet significantly if administered concurrently.
  RECOMMENDATION: Administer Cifran 500 MG Tablet 2 hours before dose OR administer Cifran 500 MG Tablet at least 2 hours after the dose of these agents.
  • Increased toxicity:
  • Caffeine and theophylline CNS stimulation when concurrent with Cifran 500 MG Tablet.
  • Cyclosporine may increase serum creatinine levels.

• Interaction with Food

  • Food: Decreases rate, but not extent, of absorption. Drug may cause GI upset; take without regard to meals (manufacturer prefers that drug is taken 2 hours after meals)
  • Dairy products, oral multivitamins, and mineral supplements: Absorption decreased by divalent and trivalent cations. These cations bind to and form insoluble complexes with quinolones. Avoid taking these substrates with Cifran 500 MG Tablet. The manufacturer states that the usual dietary intake of calcium has not been shown to interfere with Cifran 500 MG Tablet absorption.
  • Caffeine: Possible exaggerated or prolonged effects of caffeine. Cifran 500 MG Tablet reduces total body clearance of caffeine. Patients consuming regular large quantities of caffeinated beverages may need to restrict caffeine intake if excessive cardiac or CNS stimulation occurs.

• Interaction with Disease

  • Liver Disease: Any incidence of liver disease should be reported to the Doctor. Suitable adjustment in dosage can be done based on the extent of the liver impairment.
  • Osteoporosis: Suitable adjustment in dosage and duration should be made for patients who are at risk for Osteoporosis related fracture. Established treatment guidelines should be strictly followed in such cases.
  • Hypomagnesemia: Any incidences of magnesium level imbalance should be reported to the Doctor. The imbalance could occur due to a disease or due to other medication used by the patient. Regular monitoring is recommended for patients taking Ciprofloxacin.

• Ques : What is Cifran 500 mg tablet?

  Ans : Cifran 500 mg tablet belongs to a medicine group that contains Ciprofloxacin as main ingredient present. It is used for the treatment of bacterial infections. Cifran 500 mg tablet is prescribed to the patients having bronchitis and Pneumonia. It also controls gonococcal infection.

• Ques : what is the use of cifran 500 mg tablet?

  Ans : Cifran 500 mg tablet is used to treat symptoms like bacterial infections and urinary tracts. It is also used for abdominal infections and respiratory tract infections. Cifran 500 mg tablet helps to cure bone and joints infections. This medicine helps to prevent sinus infections.

• Ques : What are the side effects of Cifran 500 mg tablet?

  Ans : Cifran 500 mg tablet has many common side effects such as Vomiting and Dizziness. There are some serious side effects of this medicine like Irregular heartbeats, chest pain and Depression. In case of patients having any of the side effects or issues like Headache, abdominal disorders and dark urine. It is advised to stop the consumption of Cifran 500 mg tablet and contact to doctor as soon as possible.

• Ques : For what treatment Cifran 500 mg tablet used for?

  Ans : Cifran 500 mg tablet is used to treat various infections like abdominal and respiratory tract infections. It is also used for typhoid infections and urinary tracts. Cifran 500 mg tablet helps to cure sinus infections. This medicine helps to prevent bone and joints infections.

• Ques : How long do I need to use cifran 500 mg tablet before I see improvement in my condition?

  Ans : This medication should be consumed, until the complete eradication of the disease. Thus it is advised to use, till the time directed by your doctor. Also taking this medication longer than it was prescribed, can cause an inadequate effect on the patient's condition. So please consult your doctor.

• Ques : At what frequency do I need to use cifran 500 mg tablet?

  Ans : This medication is generally used once or twice a day, as the time interval to which this medication has an impact, is around 12 to 20 hours, but it is not the standard frequency, for using this medication. It is advised to consult your doctor before the usage, as the frequency also depends on the patient's condition.

• Ques : Should I use cifran 500 mg tablet empty stomach, before food or after food?

  Ans : This medication is common to be taken orally and the action of salts involved in this medication, do not depend on whether taking it pre-meal or post-meal. It is advised to consult a doctor before use and take it at a fixed time in a day.

• Ques : What are the instructions for the storage and disposal of cifran 500 mg tablet?

  Ans : This medication contains salts which are suitable to store only at room temperature, as keeping this medication above or below that, can cause an inadequate effect. Protect it from moisture and light. Keep this medication away from the reach of children. It is advised to dispose of the expired or unused medication, for avoiding its inadequate effect.

• Ques : Does the use of Cifran 500 MG Tablet cause diarrhea?

  Ans : Yes, the use of this medication causes diarrhea as it is an antibiotic which kills the harmful bacteria. However, it affects the helpful bacteria in your stomach or intestine and can cause diarrhea. If your symptoms are severe, consult your doctor immediately about it.

• Ques : Can I stop taking Cifran 500 MG Tablet when I feel better?

  Ans : No, do not stop taking Cifran 500 MG Tablet and complete the full course of treatment even if you feel better. Your symptoms may improve before the infection is completely cured.

• Ques : Does the use of Cifran 500 MG Tablet increase the risk of muscle damage?

  Ans : Yes the use of Cifran 500 MG Tablet increases the risk of muscle damage, commonly in the ankle. Muscle damage can happen in people of all ages who take Cifran 500 MG Tablet medication. Consult your doctor if you feel any kind of muscle pain while using this medication.

• Ques : Is Cifran 500 MG Tablet safe?

  Ans : Cifran 500 MG Tablet is relatively a safe drug. However, it is not devoid of side-effects and hence it should be taken only if prescribed by a doctor and must take appropriate dose as prescribed, frequency and duration as advised.

• Ques : Can I take Cifran 500 MG Tablet with paracetamol?

  Ans : Consult your doctor before using both the medications together as Cifran 500 MG Tablet is not known to have any clinically meaningful interaction with paracetamol.

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  https://druginfo.nlm.nih.gov/drugportal/name/ciprofloxacin

• CIPROFLOXACIN- ciprofloxacin hydrochloride tablet, film coated- Daily Med [Internet]. dailymed.nlm.nih.gov. 2017 [Cited 24 Nov 2021]. Available from:

  https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=37527eca-115e-4582-88cd-bba851ac6069

• Ciprofloxacin 500mg film-coated tablets- EMC [Internet]. www.medicines.org.uk. 2021 [Cited 3 December 2021]. Available from:

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