CIPLAR-LA 20MG TABLET

CIPLAR-LA 20MG TABLET is used for the management of high blood pressure (hypertension), angina pectoris, pheochromocytoma, essential tremor, tetralogy of Fallot cyanotic spells, and arrhythmias (such as atrial fibrillation and flutter, A-V nodal re-entrant tachycardias, and catecholamine-induced arrhythmias).

It is also used in the prevention of myocardial infarction, migraine headache. CIPLAR-LA 20MG TABLET is also helpful in treating the prevention of myocardial infarction, migraine headache.

This medication is a beta-blocking agent that attaches itself to the heart and inhibits the regular molecules from triggering the receptors. It blocks the beta-adrenergic receptors in the heart, thus slowing your heartbeat down and lowering the blood pressure. This lowers the stress placed on your heart, arteries, veins and blood vessels, decreasing the workload of the heart.

The medicine might not be suitable for everyone as it can have harmful effects on people with certain conditions. Before beginning a course of this medication, you need to notify your doctor if you are-

• Pregnant or breastfeeding, or
• Suffering from conditions such as:
• Asthma,
• Diabetes mellitus,
• Psoriasis,
• Liver or kidney problems,
• Severe heart condition.

The medicine must be taken according to the doctor’s prescription. The doctor might recommend taking it two, three or even four times a day. You must complete the course of this medication otherwise it can cause you to develop withdrawal symptoms.

• High Blood Pressure

• Angina Pectoris

• Migraine Prevention

• Anxiety

• Allergy

• Sinus Bradycardia

• Cardiogenic Shock

• Pregnancy

• Chest Pain

• Hypotension

• Cardiogenic Shock

• Light Headedness

• Confusion

• Dizziness

• Insomnia

• Fatigue

• Lethargy

• Rash

• Alopecia

• Pruritus

• Urticaria

• Contact Dermatitis

• Diarrhoea

• Nausea

• Vomiting

• How long is the duration of effect?

  The effect of this medicine lasts for about 9 hours of duration.

• What is the onset of action?

  The effect of this medicine can be observed within an hour of administration.

• Are there any pregnancy warnings?

  The use of this medicine is not recommended for pregnant women as there is a lack of conclusive evidence from clinical studies.

• Is it habit forming?

  Mild to moderate habit forming tendencies have been reported and hence requires careful administration and withdrawal.

• Are there any breast-feeding warnings?

  This medicine is not likely to be present in the breastmilk in alarming quantities. You should consult your doctor before deciding to take this medicine if you are breastfeeding.

• Is It safe with alcohol?

  Consumption of alcohol along with Propranolol is found to be unsafe. Thus it should be avoided.

• Is it safe to drive while on this medicine?

  This medicine might affect the alertness of the patient. Thus driving must be avoided if you face any symptoms related to it.

• Does this affect kidney function?

  This medicine is found to be safe to use in patient with kidney disease. Adjustment of dose is not needed.

• Does this affect liver function?

  Caution must be taken in patient with liver disease. Adjustment of dose might be needed. Kindly consult your doctor before taking it.

Below is the list of medicines, which have the same composition, strength and form as CIPLAR-LA 20MG TABLET , and hence can be used as its substitute.

• Prograin 20Mg Tablet

  Pulse Pharmaceuticals

• Arminol 20mg Tablet

  East West Pharma

• MIGRALES 20MG TABLET

  Dycine Pharmaceuticals Ltd

• Anol 20mg Tablet

  Lanark Laboratories Pvt Ltd

• Betagem 20mg Tablet

  Bondane Pharma

• Bpstat 20Mg Tablet

  Rhombus Pharma Pvt Ltd

• Are there any missed dose instructions?

  Take the missed dose as soon as you remember.

• Are there any overdose instructions?

  Report any incidence of overdose to the doctor immediately.

The medicine non-selectively blocks beta receptors sites in the heart, blood vessels, lungs and other organs. Thus pressure is lowered and blood flow in the heart and other organs is improved.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  Avoid or limit the use of alcohol while you are taking this medicine. Any activity requiring a high level of mental alertness like operating heavy machinery or driving should be avoided.

• Interaction with Medicine

  • Alpha-blockers (prazosin, terazosin): Concurrent use of beta-blockers may increase risk of orthostasis.
  • Antipyrine's clearance is reduced by 30% to 40%.
  • Cimetidine increases the plasma concentration of CIPLAR-LA 20MG TABLET and its pharmacodynamic effects may be increased.
  • Clonidine: Hypertensive crisis after or during withdrawal of either agent.
  • Drugs which slow AV conduction (digoxin): Effects may be additive with beta-blockers.
  • Epinephrine (including local anesthetics with epinephrine): CIPLAR-LA 20MG TABLET may cause hypertension.
  • Flecainide: Pharmacological activity of both agents may be increased when used concurrently.
  • Fluoxetine may inhibit the metabolism of CIPLAR-LA 20MG TABLET, resulting in cardiac toxicity.
  • Glucagon: CIPLAR-LA 20MG TABLET may blunt hyperglycemic action.
  • Haloperidol: Hypotensive effects may be potentiated.
  • Hydralazine: The bioavailability propranolol (rapid release) and hydralazine may be enhanced with concurrent dosing.
  • Insulin: CIPLAR-LA 20MG TABLET inhibits recovery and may cause hypertension and bradycardia following insulin-induced hypoglycemia. Also masks the tachycardia that usually accompanies insulin-induced hypoglycemia.
  • NSAIDs (ibuprofen, indomethacin, naproxen, piroxicam) may reduce the antihypertensive effects of beta-blockers.
  • Salicylates may reduce the antihypertensive effects of beta-blockers.
  • Sulfonylureas: Beta-blockers may alter response to hypoglycemic agents.
  • Verapamil or diltiazem may have synergistic or additive pharmacological effects when taken concurrently with beta-blockers; avoid concurrent I.V. use of both.

• Interaction with Disease

  • Administer cautiously in compensated heart failure and monitor for a worsening of the condition (efficacy of propranolol in CHF has not been demonstrated).
  • Avoid abrupt discontinuation in patients with a history of CAD; slowly wean while monitoring for signs and symptoms of ischemia.
  • Use caution in patient with PVD.
  • Use cautiously in diabetics because it can mask prominent hypoglycemic symptoms.
  • Can mask signs of thyrotoxicosis.
  • Can cause fetal harm when administered in pregnancy.
  • Use cautiously in hepatic dysfunction (dosage adjustment required).
  • Use care with anesthetic agents which decrease myocardial function.

• Ques : What is Ciplar la 20mg tablet?

  Ans : Ciplar 20 MG is a beta-blocker. It contains Propranolol as an active ingredient.

• Ques : What is the use of Ciplar la 20mg tablet?

  Ans : Ciplar tablet is used for the treatment and prevention from conditions and symptoms of diseases like hypertension, angina pectoris, migraine prevention and hypertrophic subaortic stenosis.

• Ques : What are the side effects of Ciplar la 20mg tablet?

  Ans : Possible side-effects include dizziness, diarrhea, difficulty in breathing, skin blistering and swelling of the face, lips and eyelids.

• Ques : Is Ciplar-LA over the counter product?

  Ans : Ciplar-LA is a prescription medicine and should only be taken after consulting a doctor about its required dosage and use.

• Ques : How long do I need to use ciplar la 20mg tablet before I see improvement of my conditions?

  Ans : In most of the cases, the average time taken by this medication, to reach its peak effect is within 1 day, before noticing an improvement in the condition.

• Ques : At what frequency do I need to use ciplar la 20mg tablet ?

  Ans : This medication is generally used once or twice a day, as the time interval upto which this medication has an impact is around 12 to 24 hours, but it is not the standard frequency.

• Ques : Should I use ciplar la 20mg tablet empty stomach, before food or after food?

  Ans : The salts involved in this medication work properly on an empty stomach.

• Ques : What are the instructions for storage and disposal of ciplar la 20mg tablet?

  Ans : This medication contains salts which are suitable to store at room temperature and keeping this medication above or below that, can cause an inadequate effect.

• Propranolol- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 25 April 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/propranolol

• Propranolol Tablets BP- EMC [Internet]. www.medicines.org.uk. 2019 [Cited 10 May 2019]. Available from:

  https://www.medicines.org.uk/emc/product/5888/smpc

• PROPRANOLOL HYDROCHLORIDE- propranolol hydrochloride capsule, extended release- Daily Med [Internet]. dailymed.nlm.nih.gov. 2015 [Cited 25 April 2019]. Available from:

  https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a4edba76-29b8-41fb-bf0b-d4633abba003