Ciplar-La 40Mg Tablet

Ciplar-La 40Mg Tablet is used for the management of high blood pressure (hypertension), angina pectoris, pheochromocytoma, essential tremor, tetralogy of Fallot cyanotic spells, and arrhythmias (such as atrial fibrillation and flutter, A-V nodal re-entrant tachycardias, and catecholamine-induced arrhythmias).

It is also used in the prevention of myocardial infarction, migraine headache. Ciplar-La 40Mg Tablet is also helpful in treating the prevention of myocardial infarction, migraine headache.

This medication is a beta-blocking agent that attaches itself to the heart and inhibits the regular molecules from triggering the receptors. It blocks the beta-adrenergic receptors in the heart, thus slowing your heartbeat down and lowering the blood pressure. This lowers the stress placed on your heart, arteries, veins and blood vessels, decreasing the workload of the heart.

The medicine might not be suitable for everyone as it can have harmful effects on people with certain conditions. Before beginning a course of this medication, you need to notify your doctor if you are-

• Pregnant or breastfeeding, or
• Suffering from conditions such as:
• Asthma,
• Diabetes mellitus,
• Psoriasis,
• Liver or kidney problems,
• Severe heart condition.

The medicine must be taken according to the doctor’s prescription. The doctor might recommend taking it two, three or even four times a day. You must complete the course of this medication otherwise it can cause you to develop withdrawal symptoms.

• Hypertension

• Angina Pectoris

• Migraine

• Anxiety

• Allergy

• Sinus Bradycardia

• Cardiogenic Shock

• Pregnancy

• Chest Pain

• Hypotension

• Cardiogenic Shock

• Light Headedness

• Confusion

• Dizziness

• Insomnia

• Fatigue

• Lethargy

• Cold Extremities

• Vertigo

• Syncope

• Hallucination

• Rash

• Alopecia

• Pruritus

• Urticaria

• Contact Dermatitis

• Diarrhoea

• Nausea

• Vomiting

• Stomach Discomfort

• Anorexia

• Impotence

• Thrombocytopenia

• Weakness

• Wheezing

• Bronchospasm

• Pharyngitis

• How long is the duration of effect?

  Ciplar remains active in the cardiovascular channels for 6-12 hours, depending upon the dosage cycle, if no dose is missed, the duration of effect can last up to 24 hours. If an extended release form is orally ingested, the duration of effects can last longer than 36 hours.

• What is the onset of action?

  Ciplar-La 40 MG Tablet belongs to the beta-blocker family, the onset of action can be easily felt within 2 hours of oral ingestion. As the tablet reacts quick to slow down oxygen requirement in the cardiac channels, the onset can vary from the phases of effects associated with the beta-blocking reactions for controlling adrenaline.

• Are there any pregnancy warnings?

  This medicine is not considered to be a primary prescription during pregnancy until absolutely needed. A doctor needs to be consulted on priority for discussion of the dosage amounts with the approaching trimester cycle for pregnant women.

• Is it habit forming?

  No historical records or lab studies have suggested habit-forming tendencies with prolonged use of this drug. Symptoms involving increase dosage requirements by the body should be immediately reported to the nearest physician.

• Are there any breast-feeding warnings?

  The lab research for any alarming breastfeeding warnings while administering this drug is still inconclusive till date. A physician must be consulted for controlled dosage amounts for breastfeeding women while simultaneously monitoring the side effects.

• Is It safe with alcohol?

  Cipla is not advised for consumption with alcohol. Its anti-adrenergic effects can catalyse alcoholic reactions in the body magnifying the hypertension syndrome within the body.

• Is it safe to drive while on this medicine?

  It is not recommended to drive after orally administering this tablet as one of the prime side-effects include dizziness and extreme muscle relaxation.

• Does this affect kidney function?

  Ciplar is not known to impact kidney function.

• Does this affect liver function?

  Ciplar is not known to affect liver function. One should carefully administer the dosage amounts with proper consultation from a doctor to avoid any organ deterioration effects.

Below is the list of medicines, which have the same composition, strength and form as Ciplar-La 40Mg Tablet , and hence can be used as its substitute.

• MIGRALES 40MG TABLET

  Dycine Pharmaceuticals Ltd

• Pronate 40Mg Tablet

  Linux Laboratories

• Mibeta Sr-40 Tablet

  Tas Med India Pvt Ltd

• CARDIPLAN 40MG TABLET

  Ivy Healthcare

• Probeta -40 Tablet

  Mission Research Laboratories Pvt Ltd

• Becabloc 40Mg Tablet

  Prevento Pharma

• Betabloc Forte 40mg Tablet

  USV Ltd

• Corbeta 40mg Tablet

  Piramal Healthcare Limited

• Carbnol 40mg Tablet

  Olcare Laboratories

• Prop 40Mg Tablet

  D D Pharmaceuticals

• Are there any missed dose instructions?

  For missed doses, the dose should be administered as soon as possible. There should not be a long considerable gap during two consequent doses as timing and non-adherence are known to catalyse general side effects.

• Are there any overdose instructions?

  Consult your doctor in case of overdose.

The exact mechanism of action of this drug for all the indications is not established. However, this medicine non-selectively blocks beta receptors sites in the heart, blood vessels, lungs and other organs. Thus pressure is lowered and blood flow in the heart and other organs is improved

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  Alcohol

  Ciplar is known to react adversely with multi-vitamins and diet mineral supplements. Please discuss your supplement cycle with your physician thoroughly before starting the prescription cycle for this medicine. A safe gap of 2 hours should be considered between the dosage of health supplements and this drug.

• Interaction with Medicine

  • Alpha-blockers (prazosin, terazosin): Concurrent use of beta-blockers may increase risk of orthostasis.
  • Antipyrine's clearance is reduced by 30% to 40%.
  • Cimetidine increases the plasma concentration of Ciplar-La 40Mg Tablet and its pharmacodynamic effects may be increased.
  • Clonidine: Hypertensive crisis after or during withdrawal of either agent.
  • Drugs which slow AV conduction (digoxin): Effects may be additive with beta-blockers.
  • Epinephrine (including local anesthetics with epinephrine): Ciplar-La 40Mg Tablet may cause hypertension.
  • Flecainide: Pharmacological activity of both agents may be increased when used concurrently.
  • Fluoxetine may inhibit the metabolism of Ciplar-La 40Mg Tablet, resulting in cardiac toxicity.
  • Glucagon: Ciplar-La 40Mg Tablet may blunt hyperglycemic action.
  • Haloperidol: Hypotensive effects may be potentiated.
  • Hydralazine: The bioavailability propranolol (rapid release) and hydralazine may be enhanced with concurrent dosing.
  • Insulin: Ciplar-La 40Mg Tablet inhibits recovery and may cause hypertension and bradycardia following insulin-induced hypoglycemia. Also masks the tachycardia that usually accompanies insulin-induced hypoglycemia.
  • NSAIDs (ibuprofen, indomethacin, naproxen, piroxicam) may reduce the antihypertensive effects of beta-blockers.
  • Salicylates may reduce the antihypertensive effects of beta-blockers.
  • Sulfonylureas: Beta-blockers may alter response to hypoglycemic agents.
  • Verapamil or diltiazem may have synergistic or additive pharmacological effects when taken concurrently with beta-blockers; avoid concurrent I.V. use of both.

• Interaction with Disease

  • Administer cautiously in compensated heart failure and monitor for a worsening of the condition (efficacy of propranolol in CHF has not been demonstrated).
  • Avoid abrupt discontinuation in patients with a history of CAD; slowly wean while monitoring for signs and symptoms of ischemia.
  • Use caution in patient with PVD.
  • Use cautiously in diabetics because it can mask prominent hypoglycemic symptoms.
  • Can mask signs of thyrotoxicosis.
  • Can cause fetal harm when administered in pregnancy.
  • Use cautiously in hepatic dysfunction (dosage adjustment required).
  • Use care with anesthetic agents which decrease myocardial function.

• Ques : What is Ciplar-La 40Mg Tablet?

  Ans : Ciplar is a medication which has Propranolol as an active element present in it. This medicine performs its action by obstructing the action of histamine. This drug is used to treat conditions such as Hypertension, Angina pectoris, Migraine prevention, Hypertrophic subaortic stenosis, etc.

• Ques : What are the uses of Ciplar-La 40Mg Tablet?

  Ans : This drug is used to treat lowering blood pressure, chest pains, irregular heartbeat patterns.

• Ques : What are the Side Effects of Ciplar-La 40Mg Tablet?

  Ans : Side effects include Dizziness, Headache, Sleepiness, Irregular Heart Beat etc.

• Ques : What are the instructions for storage and disposal Ciplar-La 40Mg Tablet?

  Ans : Ciplar-La 40Mg Tablet should be kept in a cool dry place and in its original pack. Make sure this medication remains unreachable to children and pets.

• Ques : Can Ciplar LA 40 Tablet be used for fast heart beat and migraine?

  Ans : Yes, Ciplar can be used for fast heartbeat and migraine.

• Ques : Are there any specific contraindications associated with the use of ciplar la 40mg tablet?

  Ans : Ciplar is contraindicated to patients having allergic reactions, heart disorders and asthma, therefore it is advised not to use this medication if the patient is having these diseases and allergic to ingredients of this medication. It is advised to not to use this medication during pregnancy and while breastfeeding.

• Ques : what precautions should you take while using Ciplar la 40mg tablet?

  Ans : Ciplar la 40mg tablet should be used with some precautions. It is important to take care of these precautions to avoid worsening conditions. Patients should not use Ciplar la 40mg tablet during pregnancy and while breastfeeding.

• Ques : Should I use ciplar la 40mg tablet empty stomach, before food or after food?

  Ans : Ciplar is advised to take after meals to avoid gastric reflux and stomach disorders. It is advised to consult a doctor before using this medication.

• Ques : What are the instructions for storage and disposal of ciplar la 40mg tablet?

  Ans : Ciplar should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets. It is important to dispose unused medications and expired medications properly to avoid adverse effects.

• Propranolol- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 25 April 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/propranolol

• Propranolol 40 mg film-coated tablets- EMC [Internet]. www.medicines.org.uk. 2018 [Cited 25 April 2019]. Available from:

  https://www.medicines.org.uk/emc/product/2904/smpc

• PROPRANOLOL HYDROCHLORIDE- propranolol hydrochloride capsule, extended release- Daily Med [Internet]. dailymed.nlm.nih.gov. 2015 [Cited 25 April 2019]. Available from:

  https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a4edba76-29b8-41fb-bf0b-d4633abba003