Ciprofloxacin 500 MG Tablet

Ciprofloxacin 500 MG Tablet is an antibiotic that is a member of the quinolone family of medicines. It is effective in treating infections that are caused by bacteria. Ciprofloxacin 500 MG Tablet is used to treat patients with bacterial infections such as pneumonia, anthrax, syphilis, gonorrhea, bronchitis, gastroenteritis and plague.

This antibiotic is also used to fight against infections of the throat, skin, ears, nose, sinus, bones, respiratory system and urinary tract. Ciprofloxacin 500 MG Tablet inhibits the regular synthesis of bacterial DNA, obstructing the process of their cell division. Therefore, it destroys the existing bacteria that are causing the infection, and it inhibits the growth of new bacteria.

Ciprofloxacin 500 MG Tablet is an anti-biotic, which is a member of the fluoroquinolone family. It helps fight against infections caused by bacteria. It is used to treat severe bacterial infections including pneumonia, respiratory or urinary tract infections, gonorrhoea, anthrax, gastroenteritis as well as infections of the sinus, bones, skin and joints. It is also effective in treating septicemic plague.

Ciprofloxacin 500 MG Tablet works by destroying the existing bacteria, that cause infection, from within the body and preventing the growth of new bacteria. The regular synthesis of DNA requires the presence of enzymes of bacterial DNA gyrase and topoisomerase IV.

Ciprofloxacin 500 MG Tablet inhibits the activity of DNA gyrase, thus preventing DNA relaxation, encouraging the damage of double-stranded DNA and inhibiting the cell division of bacteria. In this way, Ciprofloxacin 500 MG Tablet is efficient in fighting against bacterial infections within the body.

It is important to read the label of this medicine and follow the exact guidelines of the doctor’s prescription. Do not take an extra pill to make up for a missed dose, if you forget to take a dose. Instead, just continue with the next dose.

If you are allergic to Ciprofloxacin 500 MG Tablet, you will experience rashes, hives, breathing problems, swelling of the throat, tongue, face or limbs and itchiness. If you notice these symptoms, it is advisable to stop taking this medicine immediately and contact your doctor.

In some cases, patients having certain disorders, who take this antibiotic, are more susceptible to its side effects. Therefore, before starting a prescription of this medicine, you should consult the doctor if you are allergic to Ciprofloxacin 500 MG Tablet, blood disorders, conditions of the heart and low levels of magnesium in the blood.

Children and pregnant women should exercise caution before taking this medication. Although this antibiotic does treat infections, it does not treat infections like influenza, cold and viral infections.

• Bacterial Infections

• Lower Respiratory Tract Infection

• Infections Of Urinary Tract

• Prostatitis

• Hypersensitivity

• Cns Stimulation

• Discoloration Of Teeth

• Nausea

• Vomiting

• Diarrhoea

• Abdominal Pain

• Headache

• Restlessness

• Rash

• Dizziness

• Confusion

• Seizures

• Anemia

• Tremor

• Increased Liver Enzymes

• Arthralgia

• Acute Renal Failure

• How long is the duration of effect?

  The effect of this medication generally lasts for upto 8-10 hours depending upon the patient.

• What is the onset of action?

  The drug usually shows effect after 30 minutes of intake and the peak effect is felt after an hour of administration.

• Are there any pregnancy warnings?

  Ciprofloxacin 500 MG Tablet is considered safe for consumption by pregnant women. But there is a lack of conclusive evidence and hence, it must be used only when necessary after consulting a Doctor. Potential benefits and risks involved should be considered before taking the drug.

• Is it habit forming?

  No, the drug is not habit forming. But you should not exceed the prescribed amount of medication.

• Are there any breast-feeding warnings?

  The drug passes onto breast milk and is not at all recommended for breast feeding mothers.

• Is It safe with alcohol?

  The drug is know to interact with alcohol and abates its effectiveness. Therefore the consumption of these substances together is not recommended.

• Is it safe to drive while on this medicine?

  Since, it’s been reported the drug causes drowsiness and nausea it is not recommended to drive while under the effect of the drug.

• Does this affect kidney function?

  Caution must be taken in patient with kidney disease. Adjustment of the dose might be needed. Consult your doctor before taking this medication.

• Does this affect liver function?

  This medicine is probably found to be safe to use in patients with liver disease. Limited information is available to suggest dose adjustment in these patients. Kindly consult your doctor for further information.

• Are there any missed dose instructions?

  The missed dose should be taken as soon as you remember it. If the next dose is near take the next dose, avoid taking double dose.

• Are there any overdose instructions?

  If there is a case of overdose contact the nearest medical emergency as it may prove to be fatal.

Ciprofloxacin 500 MG Tablet belongs to the class fluoroquinolones. It works as a bactericidal by inhibiting the bacterial DNA gyrase enzyme, which is essential for DNA replication, transcription, repair, and recombination. This leads to expansion and destabilization of the bacterial DNA and causes cell death.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  The drug does not react well with alcohol and may reduce the effectiveness of the drug.

• Interaction with Medicine

  • CYP1A2 enzyme inhibitor
  • Enteral feedings may decrease plasma concentrations of Ciprofloxacin 500 MG Tablet probably by >30% inhibition of absorption. Ciprofloxacin 500 MG Tablet should not be administered with enteral feedings. The feeding would need to be discontinued for 1-2 hours prior to and after Ciprofloxacin 500 MG Tablet administration. Nasogastric administration produces a greater loss of Ciprofloxacin 500 MG Tablet bioavailability than does nasoduodenal administration.
  • Aluminum/magnesium products, didanosine, and sucralfate may decrease absorption of Ciprofloxacin 500 MG Tablet by greater than or equal to 90% if administered concurrently.
  RECOMMENDATION: Administer Ciprofloxacin 500 MG Tablet 2 hours before dose OR administer Ciprofloxacin 500 MG Tablet at least 4 hours and preferably 6 hours after the dose of these agents OR change to an H2-antagonist or omeprazole.
  • Calcium, iron, zinc, and multivitamins with minerals products may decrease absorption of Ciprofloxacin 500 MG Tablet significantly if administered concurrently.
  RECOMMENDATION: Administer Ciprofloxacin 500 MG Tablet 2 hours before dose OR administer Ciprofloxacin 500 MG Tablet at least 2 hours after the dose of these agents.
  • Increased toxicity:
  • Caffeine and theophylline CNS stimulation when concurrent with Ciprofloxacin 500 MG Tablet.
  • Cyclosporine may increase serum creatinine levels.

• Interaction with Disease

  • Liver Disease: Any incidence of liver disease should be reported to the Doctor. Suitable adjustment in dosage can be done based on the extent of the liver impairment.
  • Osteoporosis: Suitable adjustment in dosage and duration should be made for patients who are at risk for Osteoporosis related fracture. Established treatment guidelines should be strictly followed in such cases.
  • Hypomagnesemia: Any incidences of magnesium level imbalance should be reported to the Doctor. The imbalance could occur due to a disease or due to other medication used by the patient. Regular monitoring is recommended for patients taking Ciprofloxacin 500 MG Tablet.

• Interaction with Food

  • Food: Decreases rate, but not extent, of absorption. Drug may cause GI upset; take without regard to meals (manufacturer prefers that drug is taken 2 hours after meals)
  • Dairy products, oral multivitamins, and mineral supplements: Absorption decreased by divalent and trivalent cations. These cations bind to and form insoluble complexes with quinolones. Avoid taking these substrates with Ciprofloxacin 500 MG Tablet. The manufacturer states that the usual dietary intake of calcium has not been shown to interfere with Ciprofloxacin 500 MG Tablet absorption.
  • Caffeine: Possible exaggerated or prolonged effects of caffeine. Ciprofloxacin 500 MG Tablet reduces total body clearance of caffeine. Patients consuming regular large quantities of caffeinated beverages may need to restrict caffeine intake if excessive cardiac or CNS stimulation occurs.

• Ques : Does the use of Ciprofloxacin 500 MG Tablet cause diarrhea?

  Ans : Yes, the use of this medication causes diarrhea as it is an antibiotic which kills the harmful bacteria. However, it affects the helpful bacteria in your stomach or intestine and can cause diarrhea. If your symptoms are severe, consult your doctor immediately about it.

• Ques : Can I stop taking Ciprofloxacin 500 MG Tablet when I feel better?

  Ans : No, do not stop taking Ciprofloxacin 500 MG Tablet and complete the full course of treatment even if you feel better. Your symptoms may improve before the infection is completely cured.

• Ques : Does the use of Ciprofloxacin 500 MG Tablet increase the risk of muscle damage?

  Ans : Yes the use of Ciprofloxacin 500 MG Tablet increases the risk of muscle damage, commonly in the ankle. Muscle damage can happen in people of all ages who take Ciprofloxacin 500 MG Tablet medication. Consult your doctor if you feel any kind of muscle pain while using this medication.

• Ques : Is Ciprofloxacin 500 MG Tablet safe?

  Ans : Ciprofloxacin 500 MG Tablet is relatively a safe drug. However, it is not devoid of side-effects and hence it should be taken only if prescribed by a doctor and must take appropriate dose as prescribed, frequency and duration as advised.

• Ques : Can I take Ciprofloxacin 500 MG Tablet with paracetamol?

  Ans : Consult your doctor before using both the medications together as Ciprofloxacin 500 MG Tablet is not known to have any clinically meaningful interaction with paracetamol.

• Ciprofloxacin- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 24 April 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/ciprofloxacin

• Ciprofloxacin- DrugBank [Internet]. Drugbank.ca. 2019 [Cited 27 April 2019]. Available from:

  https://www.drugbank.ca/drugs/DB00537

• Ciplox (Ciprofloxacin): Uses, Side Effects, Dosage- Drugs Bank [Internet]. drugsbanks.com. 2018 [Cited 27 April 2019]. Available from:

  https://www.drugsbanks.com/ciplox/