Clobazam

Clobazam is primarily prescribed for treating severe anxiety and epilepsy (seizures). It is assumed to work by suppressing the excessive and abnormal activity of the brain nerve cells.

Clobazam is generally prescribed in combination with another drug. It essentially treats a particular kind of seizure disorder called Lennox-Gastaut Syndrome (LGS). It can also be prescribed in the treatment of other problems as per the discretion of your doctor.

The drug is a part of a class of medicines called benzodiazepine. Although how Clobazam particularly works is yet unknown, the general idea is that it controls the action of gamma-aminobutyric, which is a chemical released by the brain.

The drug should be taken orally, either with food or without. It has to be swallowed whole. In case you cannot consume Clobazam whole, mix it with apple sauce and swallow immediately. You can drink water to wash down the mixture. Any extra mixture should not be stored.

In case of a missed dosage, take the drug as soon as possible. If it is time for your next dose, it is best to skip the missed dose and go back to your normal dose schedule. The drug does cause a few side effects such as dizziness and allergies. But if any of the following side effects become very severe be sure to get in touch with a doctor. They are-

• allergic reaction, which may include hives, itching or problems with breathing
• changes in appetite and vision
• hallucinations and confusion along with mood swings
• cough and itchy throat
• problems with speech
• bruising and bleeding

It is important to take certain safety measures when taking Clobazam. For example, driving should be avoided as one of the side effects of the drug includes dizziness. Alcohol consumption when taking this drug can lead to drowsiness and aggravate other side effects too. Clobazam should not be stopped suddenly. This can lead to seizures or adverse mental side effects.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.

• Seizures Associated With Lennox-Gastaut Syndrome

• Anxiety

• Epilepsy

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.

• Allergy

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.

• Constipation

• Fever

• Insomnia

• Sleepiness

• Slurred Speech

• Tiredness

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.

• How long is the duration of effect?

  The effect of this medicine can be observed for an average duration of 3 to 4 days.

• What is the onset of action?

  The peak effect of this medicine can be observed in 0.5 to 4 hours.

• Are there any pregnancy warnings?

  This medicine is not recommended for pregnant women.

• Is it habit forming?

  Habit forming tendency has been reported

• Are there any breast-feeding warnings?

  This medicine is not recommended in breastfeeding women.

• Is It safe with alcohol?

  Consumption of alcohol must be avoided while taking this medicine as it may cause excessive drowsiness with alcohol.

• Is it safe to drive while on this medicine?

  This drug might affect the consciousness of the patient thus driving must be avoided while taking this medicine.

• Does this affect kidney function?

  Caution must be taken while using this medicine in patients with kidney disease. Adjustment of dose might be needed. Kindly consult your doctor before taking it.

• Does this affect liver function?

  Caution must be taken while using this medicine in patients with liver disease. Adjustment of dose might be needed. Kindly consult your doctor before taking it.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.

• Missed Dose instructions

  If you miss a dose of Clobazam, take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

• Are there any overdose instructions?

  Seek emergency medical treatment or contact the doctor in case of an overdose.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.

• India

• United States

• Japan

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.

Below is the list of medicines, which contains Clobazam as ingredient

• Cloba Mt 10 MG Tablet

  Intas Pharmaceuticals Ltd

• Zac 5 MG Tablet

  Orchid Chemicals & Pharmaceuticals Ltd

• Frisium 5 MG Tablet

  Sanofi India Ltd

• Clozam 10 MG Tablet

  Abbott Healthcare Pvt. Ltd

• Clobakem 5 MG Tablet

  Alkem Laboratories Ltd

• Kobazam 5 MG Tablet

  Kivi Labs Ltd

• Yogazam 5 MG Tablet

  Micro Labs Ltd

• Lobacor 5 MG Tablet

  Emcure Pharmaceuticals Ltd

• Lobazam Md 0.25 MG Tablet MD

  Sun Pharma Laboratories Ltd

• Clozam 5 MG Tablet

  Abbott Healthcare Pvt. Ltd

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.

Clobazam belongs to the class benzodiazepines. It works by increasing the effect of GABA which is an inhibitory neurotransmitter which results by increasing the permeability of chloride ions into the neuron thus result in hyperpolarization and stabilization of neuron.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  Consumption of alcohol is not recommended if the patient is receiving Clobazam. Inform the doctor if you are an alcoholic. Any symptoms of dizziness, difficulty in concentration should be reported to the doctor. Dose adjustments or an alternate medicine should be considered based on the clinical condition.

• Interaction with Lab Test

  Information not available.

• Interaction with Medicine

  Amitriptyline

  Clobazam may increase the concentration of amitriptyline. Inform the doctor if you are receiving these medicines. Suitable dose adjustments are to be made based on the clinical condition or an alternate medicine should be considered.

  Ethinyl Estradiol

  The desired effect of contraceptive pills will not be achieved if these medicines are used together. A nonhormonal form of contraceptive is recommended during and 28 days after Clobazam. Appropriate dose adjustments or an alternate medicine should be considered under the doctor's supervision.

  Opoids

  Opioids like morphine, codeine, tramadol, hydrocodone or any cough preparations containing these medicines should be avoided when you are on Clobazam or other benzodiazepines. Appropriate dose adjustments are to be made if coadministration is needed and monitoring of sedation, breathlessness, and hypotension is necessary.

  Antihypertensives

  Clobazam may further lower the blood pressure when taken with antihypertensives. Inform the doctor if you are receiving these medicines. Any symptoms of dizziness, lightheadedness should be reported to the doctor. Dose adjustments are to be made based on the clinical condition or an alternate medicine should be considered.

• Interaction with Disease

  Depression

  Clobazam should be used with caution in the patients with the history of depression or a family history of depression. The prescription size should be limited. Any symptoms of mood changes should be reported to the doctor immediately.

• Interaction with Food

  Information not available.

• Ques : What is Clobazam?

  Ans : Clobazam is a benzodiazepine.

• Ques : What are the uses of Clobazam?

  Ans : It essentially treats a particular kind of seizure disorder called Lennox-Gastaut Syndrome (LGS).

• Ques : How long do I need to use Clobazam before I see improvement in my condition?

  Ans : In most of the cases, the average time taken by this medication to reach its peak effect is around 1 day to 1 week. Please consult your doctor for the time period you need to use this medication.

• Ques : At what frequency do I need to use Clobazam?

  Ans : This medication is generally used once or twice a day. It is advised to consult your doctor before the usage, as the frequency also depends on the patient's condition.

• Ques : Should I use Clobazam empty stomach, before food or after food?

  Ans : The drug should be taken orally, either with food or without.

• Ques : What are the instructions for the storage and disposal of Clobazam?

  Ans : It should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets.

• Ques : How long does Clobazam take to work?

  Ans : Usually, Clobazam starts working soon after taking it. However, it may take some days to kill all the harmful bacteria and make you feel better.

• Ques : What if I don't get better after using Clobazam?

  Ans : Inform your doctor if you don't feel better after finishing the full course of treatment. Also, inform him if your symptoms are getting worse while using this medicine.

• Ques : Is Clobazam habit forming?

  Ans : No addiction issues have been reported yet.

• Ques : Does Clobazam cause depression?

  Ans : No, Clobazam does not cause depression, but it can cause recurrence of pre-existing depression.

• Clobazam-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 1 June 2022].Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/clobazam

• Clobazam-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 1 June 2022].Available from:

  https://go.drugbank.com/drugs/DB00349

• Clobazam Tablet,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 1 June 2022].Available from:

  https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=CLOBAZAM