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Overview

Clonafit Plus Tablet

Manufacturer :  Mankind Pharma Ltd
Medicine Composition :  Clonazepam, Escitalopram
Prescription vs OTC : Prescription by Doctor not required

About Clonafit Plus Tablet

Clonafit Plus Tablet is used to treat and prevent generalized anxiety disorder and depression. This medicine is a combination of an anti-epileptic and an anti-convulsant in combination with an antidepressant. This medicine is administered to control panic attacks.

Belonging to a cluster of drugs called benzodiazepines. It works by inducing a calming effect on your nerves and brain. The most common side effects include

  • drowsiness
  • dizziness
  • fatigue
  • loss of focus
  • increased secretion of saliva in the mouth.

Let your doctor know if you have been feeling depressed for no particular reason. If you notice any change in the way you behave with people around you. Other side effects include rash, itching, sore throat and fever.

This medication can increase suicidal thoughts and behaviours especially amongst teenagers, children, and young adults if taken in excess amounts. Hence, this drug should only be taken under a doctor’s prescription.

This medication is normally prescribed to be taken once a day. The usual dose is 10-20 mg for adults as well as children. It is not suitable for everyone as it might cause harmful effects on people suffering from certain conditions.

If you are suffering from irregular heartbeats or are allergic to certain ingredients present in the medicine, it is advisable to consult with the doctor first. Also, this medication might have a harmful effect on a pregnant woman. Consult with the doctor if you have a history of liver disease or kidney disease.

Take exactly as directed (do not increase dose or frequency); may cause physical and/or psychological dependence. While using this medication, do not use alcohol and other prescription or OTC medications (especially pain medications, sedatives, antihistamines, or hypnotics) without consulting prescriber.

    What are the uses of Clonafit Plus Tablet

    • Anxiety Disorder

    What are the contraindications of Clonafit Plus Tablet ?

    What are the side effects of Clonafit Plus Tablet ?

    Key highlights of Clonafit Plus Tablet

    • How long is the duration of effect?

      The effect of this medicine lasts for an average duration of 6 to 8 hours in adults. This duration increases to 12 hours in infants and children.

    • What is the onset of action?

      The effect of this medicine can be observed within 30 to 40 minutes of administration.

    • Are there any pregnancy warnings?

      This medicine is not recommended during pregnancy until absolutely necessary. It is known to cause harm to the fetus. Infants born to a mother taking this drug during pregnancy may show withdrawal symptoms.

    • Is it habit forming?

      Habit forming tendencies were reported in some cases especially if the usage is for an extended period of time. A gradual withdrawal of the drug i.e. decrease in dosing over a period of time is suggested in such cases.

    • Are there any breast-feeding warnings?

      This medicine is not recommended for use in women who are lactating as the likelihood of side effects on the infant is very high. However, the potential benefits and associated risks should be discussed with your doctor in cases where it is necessary to take this medicine.

    • Is It safe with alcohol?

      It is unsafe to consume alcohol with this medicine. Kindly consult your doctor.

    • Is it safe to drive while on this medicine?

      This medicine may cause side effects that affects the consciousness of the patient. Thus driving must be avoided while taking this medicine.

    • Does this affect kidney function?

      This medicine is probably safe to be used in patients with kidney disease. Availability of limited data suggests that adjustment of dose might not be needed. Kindly consult your doctor before this medicine.

    • Does this affect liver function?

      Caution must be taken in patients with liver disease. Adjustment of dose might be needed. Kindly consult your doctor before taking it.

    What are the substitutes for Clonafit Plus Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Clonafit Plus Tablet , and hence can be used as its substitute.

    What are the dosage instructions?

    • Missed Dose instructions

      Take the missed dose as soon as you remember. If it is time for the next scheduled dose then the missed dose can be skipped. Contact your doctor and seek advice if you there are any doubts regarding dosage.

    • Are there any overdose instructions?

      Contact a doctor immediately if an overdose is suspected. Symptoms of an overdose like drowsiness, confusion or fainting should be reported immediately.

    How does this medication work?

    Clonafit Plus Tablet is an anti-convulsant and an ant-epileptic which acts like a tranquilizer. It inhibits the synaptic transmission that occurs in the central nervous system. It also reduces the use of serotonin by neurons and is used to treat seizures and anxiety. It also acts as a selective inhibitor of serotonin (5-HT) re-uptake with high affinity for the primary binding site. Binds to an allosteric site on the serotonin transporter, with a 1000 fold lower affinity.

      What are the interactions of Clonafit Plus Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Alcohol

        Additive CNS depression has been reported with benzodiazepines; avoid or limit alcohol.
      • Interaction with Medicine

        • The combined use of Clonafit Plus Tablet and valproic acid has been associated with absence seizures.
        • Carbamazepine, rifampin, rifabutin may enhance the metabolism of Clonafit Plus Tablet and decrease its therapeutic effect; consider using an alternative sedative/hypnotic agent.
        • Cimetidine, ciprofloxacin, clarithromycin, clozapine, CNS depressants, diltiazem, disulfiram, digoxin, erythromycin, ethanol, fluconazole, fluoxetine, fluvoxamine, grapefruit juice, isoniazid, itraconazole, ketoconazole, labetalol, levodopa, loxapine, metoprolol, metronidazole, miconazole, nefazodone, omeprazole, phenytoin, rifabutin, rifampin, troleandomycin, verapamil may increase the serum level and/or toxicity of clonazepam; monitor for altered benzodiazepine response.
      • Interaction with Disease

        This medication interacts with the following disease Seizure disorders, Closed-Angle Glaucoma, and Respiratory disorders.

      FAQs about Clonafit Plus Tablet

      • Ques : What is Clonafit Plus Tablet?

        Ans : Clonafit Plus Tablet is a combination medicine which is used for the treatment of patients suffering from both depression and anxiety disorders. It contains Clonazepam and Escitalopram as active ingredients. Clonafit Plus Tablet works by increasing the activity of serotonin in the brain; enhancing the activity of gamma aminobutyric acid (GABA) neurotransmitter.

      • Ques : What is the use of Clonafit Plus Tablet?

        Ans : Clonafit Plus Tablet is used for the treatment and prevention from conditions and symptoms of diseases like major depressive disorder, anxiety disorder, and panic disorder. Besides these, it can also be used to treat depression, agitation, cognitive disorder, and treatment of seizure disorder.

      • Ques : What are the side effects of Clonafit Plus Tablet?

        Ans : This is a list of possible side-effects which may occur due to the constituting ingredients of Clonafit Plus Tablet. This is not a comprehensive list. These side-effects have been observed and not necessarily occur. Some of these side-effects may be serious. These include palpitations, lethargy, skin rash, insomnia, and tremor. Apart from these, using this medicine may further lead to nausea, ejaculation disorder, fatigue, back pain, and urinary tract infection. If any of these symptoms occur often or on daily basis, a doctor should be urgently consulted.

      • Ques : What are the instructions for storage and disposal of Clonafit Plus Tablet?

        Ans : Clonafit Plus Tablet should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets. A doctor should be consulted regarding the dosage of Clonafit Plus Tablet. The patient should consult a doctor for its further uses and side effects and should inform the doctor about any ongoing medications and treatment before using to avoid undesirable effects.

      • Ques : How long do I need to use Clonafit Plus Tablet before I see improvement in my condition?

        Ans : In most of the cases, the average time taken by this medication to reach its peak effect is around 1 day to 3 months, before noticing an improvement in the condition. But the same duration is not mandatory for everyone and so, it is not a standard time period for this medication's action. Please consult your doctor, for the time period you need to use this medication.

      • Ques : At what frequency do I need to use Clonafit Plus Tablet?

        Ans : "This medication is generally used once or twice a day, as the time interval to which this medication has an impact, is around 12 to 24 hours, but it is not the standard frequency, for using this medication. It is advised to consult your doctor before the usage, as the frequency also depends on the patient's condition. "

      • Ques : Should I use Clonafit Plus Tablet empty stomach, before food or after food?

        Ans : This medication is common to be taken orally and the action of salts involved in this medication, do not depend on whether taking it pre-meal or post-meal. It is advised to consult a doctor before use and take it at a fixed time in a day.

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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