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Overview

Colette 0.25Mg Tablet

Manufacturer :  Cipla Ltd
Medicine Composition :  Cabergoline
Prescription vs OTC : Prescription by Doctor required

About Colette 0.25Mg Tablet

Colette 0.25Mg Tablet helps in the treatment of disorders that occur as a result of very high levels of prolactin hormone in the body. This may occur because of tumour development in the pituitary gland or other reasons that are yet unknown.

Colette 0.25Mg Tablet is primarily prescribed for the treatment of hyperprolactinemic disorders, either idiopathic or due to pituitary adenomas. The drug is basically a dopamine receptor agonist, which prevents the pituitary gland from producing large quantities of prolactin.

The drug may be detrimental to patients who have health complications related to high blood pressure, heart disease, disorder of the kidney or lungs. People who are allergic to any component present in Colette 0.25Mg Tablet, should also consult their medical adviser before taking the medicine.

Take the drug according to the directions given in the prescription. The treatment course should not be stopped midway without the advice of your doctor. In this case the side effects of Colette 0.25Mg Tablet may worsen, resulting in more complications. The drug is meant to be taken by mouth wither with food or without. In case you do miss a dose, contact your doctor and seek advice.

Confusion, gas, headache, dizzy spells, weakness, anxiety, pain in the breasts, pimples and a runny nose are a few side effects of Colette 0.25Mg Tablet that you should be aware of.

An overdose may produce nasal congestion, syncope, hallucinations, or hypotension. Measures to support blood pressure should be taken if necessary.

Patient should be instructed to notify physician if she suspects she is pregnant, becomes pregnant, or intends to become pregnant during therapy with cabergoline. A pregnancy test should be done if there is any suspicion of pregnancy and continuation of treatment should be discussed with physician.

Initial Dose: 0.25 mg twice weekly; the dose may be increased by 0.25 mg twice weekly up to a maximum of 1 mg twice weekly according to the patient's serum prolactin level. Dosage increases should not occur more rapidly than every 4 weeks.

Once a normal serum prolactin level is maintained for 6 months, the dose may be discontinued and prolactin levels monitored to determine if cabergoline is still required. The durability of efficacy beyond 24 months of therapy has not been established.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Endocrinologist before using this medicine.

    What are the uses of Colette 0.25Mg Tablet

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Endocrinologist before using this medicine.

    What are the contraindications of Colette 0.25Mg Tablet ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Endocrinologist before using this medicine.

    What are the side effects of Colette 0.25Mg Tablet ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Endocrinologist before using this medicine.

    Key highlights of Colette 0.25Mg Tablet

    • Is It safe with alcohol?

      Taking Colette 0.25Mg Tablet together with alcohol may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating.

    • Are there any pregnancy warnings?

      Colette 0.25Mg Tablet is probably safe to use during pregnancy.
      Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.

    • Are there any breast-feeding warnings?

      Colette 0.25Mg Tablet is probably unsafe to use during breastfeeding. Please consult your doctor.

    • Is it safe to drive while on this medicine?

      Should be cautious while driving or using machines.

    • Does this affect kidney function?

      There is no data available. Please consult doctor before consuming the drug.

    • Does this affect liver function?

      There is no interaction between liver impairment and consuming this drug. So dose alteration is not needed.

    • How long is the duration of effect?

      The effect of this drug remain for about 24 - 48 hours.

    • What is the onset of action?

      The effect of this medicine is initiated within 60 minutes after its administration.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Endocrinologist before using this medicine.

    What are the substitutes for Colette 0.25Mg Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Colette 0.25Mg Tablet , and hence can be used as its substitute.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Endocrinologist before using this medicine.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      If you miss a dose of Colette 0.25Mg Tablet, skip it and continue with your normal schedule. Do not double the dose.

    • Are there any overdose instructions?

      Seek emergency medical treatment or contact the doctor in case of an overdose.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Endocrinologist before using this medicine.

    How does this medication work?

    Colette 0.25Mg Tablet is an activator for pituitary lactotroph cells, also known as prolactin cells. When the drug was used on rats, the prolactin secretion was greatly increased through the inhibition of the pituitary’s lactotroph cells.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Endocrinologist before using this medicine.

      What are the interactions of Colette 0.25Mg Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Medicine

        • Additive hypotensive effects may occur when cabergoline is administered with antihypertensive medications; dosage adjustment of the antihypertensive medication may be required.
        • Decreased effect: Dopamine antagonists (eg, phenothiazines, butyrophenones, thioxanthenes, or metoclopramide) may reduce the therapeutic effects of cabergoline and should not be used concomitantly.
      • Interaction with Disease

        • Use caution when patients are receiving other medications which may reduce blood pressure.
        • Not indicated for the inhibition or suppression of physiologic lactation since it has been associated with cases of hypertension, stroke, and seizures.
        • Because cabergoline is extensively metabolized by the liver, careful monitoring in patients with hepatic impairment is warranted.
        • Female patients should instruct the physician if they are pregnant, become pregnant, or intend to become pregnant. Should not be used in patients with pregnancy-induced hypertension unless benefit outweighs potential risk.
        • Do not give to postpartum women who are breast-feeding or planning to breast-feed. In all patients, prolactin concentrations should be monitored monthly until normalized.

      FAQs about Colette 0.25Mg Tablet

      • Ques : What is Colette 0.25Mg Tablet and what is it used for?

        Ans : Colette 0.25Mg Tablet contains Colette 0.25Mg Tablet, which belongs to a group of medicines that reduces the level of prolactin. It is used to treat medical problems such as galactorrhoea due to abnormally high levels of prolactin. It is also used to stops breast milk production (lactation) in case of stillbirth, abortion or miscarriage.

      • Ques : How and in what dose should I take Colette 0.25Mg Tablet?

        Ans : Take this medicine, as per the advice of your doctor. The advised dose and duration depend on your medical condition. It is recommended to take this medicine with food or after food, to reduce the chances of nausea or vomiting.

      • Ques : What are the possible side effects of using Colette 0.25Mg Tablet?

        Ans : During the initial days of treatment, this medication may decrease your blood pressure which could make you feel dizzy. Your doctor may suggest you to monitor your blood pressure regularly during these days. Common side-effects are dizziness, vertigo, stomach pain, indigestion, fatigue, and weakness. If any of these side effects bother you, immediately consult your doctor.

      References

      • Cabergoline-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 18 June 2022].Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/cabergoline

      • Cabergoliner-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 18 June 2022].Available from:

        https://go.drugbank.com/drugs/DB00248

      • CABERGOLINE tablet,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 18 June 2022].Available from:

        https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=CABERGOLINE

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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