Colihenz P -400 Tablet

Colihenz P -400 Tablet is prescribed for the treatment of acute stroke. This medicine is a combination of Citicoline and Piracetam. As a medicine, it is taken orally as a dietary supplement. This medication has also been found to influence the cognitive abilities and improve nerve transmission.

Citicoline is a chemical that naturally occurs in the body which is responsible for regulating many vital processes in the brain as well in as the body. Whereas Piracetam is structurally similar to aminobutyric acid and it improves & facilitates microcirculation in the blood vessels.

Colihenz P -400 Tablet works by increasing a brain chemical called phosphatidylcholine which improves brain function. Colihenz P -400 Tablet also decreases brain tissue damage during a brain injury by repairing damaged nerve cells.

It is also used for treating alzheimer's disease and other types of dementia, cerebrovascular disease such as stroke, head trauma, age-related memory loss, attention deficit-hyperactive disorder, parkinson’s disease, and glaucoma.

You are advised to not take this medicine if you have an allergy towards any of its ingredients or if you suffer from hypertonia. It is also not recommended for anyone who is 18 years of age or younger.

Medicines like levodopa and meclofenoxate can interfere with the action of Colihenz P -400 Tablet so inform your doctor if you are taking these medicines before starting the medication. This medicine can be taken with or after food. Adequate amounts of fluids should be consumed while taking this medicine.

• Acute Ischemic Stroke

• Allergy

  This medicine is not recommended for use if you have a known history of allergy to Colihenz P -400 Tablet or any other ingredients present along with it.

• Hypertonia

  This medicine is not recommended for use in patient having abnormal muscle tension and stiffness due to nerve damage in the brain. This condition is also present in people who have had a brain surgery to remove certain specific nerves.

• Pediatric Use

  This medicine is not recommended for use in children who are aged 18 or below.

• Cerebral Hemorrhage

  This medication is not recommended for use if you have a ruptured blood vessel and localized bleeding in the brain.

• Huntington's Disease

  This medication is not recommended for use in patients suffering from a genetic disorder where the brain cell die quickly causing a deterioration of mental and physical abilities over time.

• Weight Gain

• Hyperactivity

• Stomach Pain

• Nervousness

• Diarrhoea

• Decreased Blood Pressure

• How long is the duration of effect?

  The amount of time for which effects of this medicine lasts is unknown.

• What is the onset of action?

  The time taken for this medicine to show it's effect is not clinically established.

• Are there any pregnancy warnings?

  This medicine is not recommended for use when you are pregnant.

• Is it habit forming?

  No habit forming tendencies were reported.

• Are there any breast-feeding warnings?

  This medicine is not recommended for use by women who are breastfeeding.

• Does this affect kidney function?

  This medication is not recommended for use if you have a severe impairment of the kidney function.

• Does this affect liver function?

  This medication is not recommended for use if you have an impairment of the liver function.

Below is the list of medicines, which have the same composition, strength and form as Colihenz P -400 Tablet , and hence can be used as its substitute.

• Strolin P 400 Tablet

  Torrent Pharmaceuticals Ltd

• Cognolin P Tablet

  Cipla Ltd

• Citistar-Pm Tablet

  Lupin Ltd

• Citilin P 500 Mg/400 Mg Tablet

  Unichem Laboratories Ltd

• Citinerve P Tablet

  USV Ltd

• Somazina Plus 400 Tablet

  Dr Reddy s Laboratories Ltd

• Clinaxon-P Tablet

  Abbott India Ltd

• Topline Plus Tablet

  Crescent Therapeutics Ltd

• Citico Plus 500 Mg/400 Mg Tablet

  Zydus Cadila

• Cognitam Plus 500 Mg/400 Mg Tablet

  Linux Laboratories

• Missed Dose instructions

  Take the missed dose as soon as you remember. If it is almost time for the next scheduled dose then the missed dose can be skipped.

• Are there any overdose instructions?

  Contact your doctor if an overdose with this medicine is suspected.

The exact mechanism of action of this medication is yet to be determined. It is believed to work by increasing the concentrations of chemicals like phosphatidylcholine, methionine, betaine, cytidine etc in the brain. These chemicals enter different metabolic pathways and help in exerting the action of this medicine.

It also acts by impacting the release of certain neurotransmitters in the brain. It improves and facilitates microcirculation in the blood vessels. It increases the flow of blood and oxygen uptake by activating acetylcholine.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

test

• Interaction with Alcohol

  Alcohol

  Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

• Interaction with Lab Test

  Lab

  Information not available.

• Interaction with Medicine

  Levodopa

  Colihenz P -400 Tablet should be used with caution in patients taking levodopa or other medicines for the management of Parkinson's disease.

  Meclophenoxate

  Report the use of either of the medicine to the doctor. Caution is advised while using these medicines together. Your doctor may determine the best course of treatment in such cases.

  Warfarin

  Report the use of either of the medicine to the doctor. You may require a dose adjustment and more frequent clinical monitoring to use these medicines together.

  Aspirin

  Report the use of either of the medicine to the doctor. You may require a dose adjustment and more frequent clinical monitoring to use these medicines together.

  Thyroxine

  Report the use of either of the medicine to the doctor. You may require a dose adjustment and more frequent clinical monitoring to safely use these medicines together.

• Interaction with Disease

  Disease

  Information not available.

  Kidney Disease

  This medication should be used with caution in patients suffering from a kidney disease. The dosing needs to be modified depending on the creatinine clearance levels. It is not recommended for use in patients having a severe impairment of the kidney function.

  Bleeding Disorders

  This medicine should be used with caution in patients having an active bleeding disorder. Suitable tests should be performed to determine the safe use of this medicine.

• Interaction with Food

  Food

  Information not available.

• Ques : What is Colihenz P -400 Tablet?

  Ans : Colihenz P -400 Tablet is prescribed for the treatment of acute stroke. This medicine is a combination of Citicoline and Piracetam. This medication has also been found to influence the cognitive abilities and improve nerve transmission.

• Ques : How long do I need to use Colihenz P -400 Tablet before I see improvement in my condition?

  Ans : This medication is to be taken till the time you see an improvement in your health conditions.

• Ques : At what frequency do I need to use Colihenz P -400 Tablet?

  Ans : This medication should be taken in the dosage as prescribed by the doctor.

• Ques : Should I use Colihenz P -400 Tablet empty stomach, before food or after food?

  Ans : This medication should be taken after food in a prescribed dosage.

• Ques : What are the instructions for the storage and disposal of Colihenz P -400 Tablet?

  Ans : This medication should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

• Piracetam- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 24 March 2020]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/piracetam

• Piracetam- DrugBank [Internet]. Drugbank.ca. 2020 [Cited 24 March 2020]. Available from:

  https://www.drugbank.ca/drugs/DB09210

• Citicoline- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 24 March 2020]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/citicoline

• Citicoline- DrugBank [Internet]. Drugbank.ca. 2020 [Cited 24 March 2020]. Available from:

  https://www.drugbank.ca/drugs/DB24153